Nina Baruch,Jennifer Burgess,Manjunadh Pillai et al.
Nina Baruch et al.
Depression is a common comorbidity in dementia. Randomised controlled studies of antidepressants do not show a significant improvement in depressive symptoms in patients with comorbid dementia and are known to lead to an increase in side ef...
Sophie Behrman,Belinda Lennox
Sophie Behrman
The awareness and understanding of autoimmune encephalitis are blossoming in neurology, and patients are being diagnosed and successfully treated with immunotherapy. The diverse symptomatology associated with autoimmune encephalitis means t...
Optimising prescribing for patients with severe mental illness: the need for criteria [0.03%]
精神疾病患者的处方优化:制定标准的必要性
Aoife Carolan,Dolores Keating,Judith Strawbridge et al.
Aoife Carolan et al.
The life expectancy of people with severe mental illness (SMI) is considerably shorter than those without SMI. Multimorbidity and poorer physical health outcomes contribute significantly to this health inequality. Psychotropic medicines, in...
Use of mobile apps and technologies in child and adolescent mental health: a systematic review [0.03%]
移动应用和儿童及青少年精神卫生技术的使用:系统性综述
Mallika Punukollu,Mafalda Marques
Mallika Punukollu
Question: This review will aim to critically evaluate the currently available literature concerning the use of online mobile-based applications and interventions in the detection, management and maintenance of children an...
Six decades of preventing and treating childhood anxiety disorders: a systematic review and meta-analysis to inform policy and practice [0.03%]
六十年来儿童焦虑障碍的预防和治疗:系统回顾及元分析指导政策与实践
Christine Schwartz,Jenny Lou Barican,Donna Yung et al.
Christine Schwartz et al.
Question: Anxiety disorders are the most prevalent childhood mental disorders. They also start early and persist, causing high individual and collective costs. To inform policy and practice, we therefore asked: What is th...
One step closer to personalised prescribing of antidepressants: using real-world data together with patients and clinicians' preferences [0.03%]
朝个性化抗抑郁药处方迈进了一步:结合真实世界数据和患者及临床医生的偏好
Catherine Kernot,Anneka Tomlinson,Astrid Chevance et al.
Catherine Kernot et al.
Dimitris Mavridis
Dimitris Mavridis
In most, if not all, healthcare conditions, there is a plethora of competing interventions with few head-to-head comparisons and classical meta-analysis fails to handle simultaneously the multiple comparisons among interventions. Network me...
Orestis Efthimiou
Orestis Efthimiou
Meta-analysis of rare events requires special considerations regarding which statistical method to use. This is because standard meta-analytical models are not well suited for the task, especially when some of the identified studies have re...
Cortisol awakening response in children and adolescents with autism spectrum disorder: a systematic review and meta-analysis [0.03%]
儿童和青少年自闭症谱系障碍的皮质醇觉醒反应:系统回顾和荟萃分析
Julie A Hadwin,Emma Lee,Robert Kumsta et al.
Julie A Hadwin et al.
Background: The cortisol awakening response (CAR) is characterised by an increase in cortisol in the 30 to 60 min after waking. Research has found significant associations between an atypical CAR and symptoms of stress an...
Trends in antidepressant prescriptions in children and young people in England, 1998-2017: protocol of a cohort study using linked primary care and secondary care datasets [0.03%]
英格兰1998至2017年间儿童及年轻人抗抑郁药处方情况趋势:基于初级和二级护理数据集的同辈群组研究方案
Ruth H Jack,Chris Hollis,Carol Coupland et al.
Ruth H Jack et al.
Introduction: Increasing numbers of children and young people (CYP) are receiving prescriptions for antidepressants. This is the protocol of a study aiming to describe the trends and variation in antidepressant prescripti...