Maria J Gonzalez-Rellan,Eva Novoa,Natalia da Silva Lima et al.
Maria J Gonzalez-Rellan et al.
Objective: p63 is a transcription factor within the p53 protein family that has key roles in development, differentiation and prevention of senescence, but its metabolic actions remain largely unknown. Herein, we investig...
Transcolonic endoscopic appendicectomy: a spectacular but unconvincing proposition [0.03%]
经直肠内镜阑尾切除术：令人惊叹但缺乏说服力的观点
Shail Shah,Marius Taniel Paraoan
Shail Shah
Zsanett Jancsó,Alexandra Demcsák,Miklós Sahin-Tóth
Zsanett Jancsó
Interferon regulatory factor 1 (IRF1) controls the metabolic programmes of low-grade pancreatic cancer cells [0.03%]
干扰素调节因子1(IRF1)控制低级别胰腺癌细胞的代谢程序
Gabriele Alfarano,Matteo Audano,Pierluigi Di Chiaro et al.
Gabriele Alfarano et al.
Objective: Pancreatic ductal adenocarcinomas (PDACs) include heterogeneous mixtures of low-grade cells forming pseudoglandular structures and compact nests of high-grade cells organised in non-glandular patterns. We previ...
Tacrolimus-binding protein FKBP8 directs myosin light chain kinase-dependent barrier regulation and is a potential therapeutic target in Crohn's disease [0.03%]
他克莫司结合蛋白FKBP8在肌球蛋白轻链激酶依赖的屏障调节中发挥作用并可能成为治疗克罗恩病的新靶点
Li Zuo,Wei-Ting Kuo,Feng Cao et al.
Li Zuo et al.
Objective: Intestinal barrier loss is a Crohn's disease (CD) risk factor. This may be related to increased expression and enzymatic activation of myosin light chain kinase 1 (MLCK1), which increases intestinal paracellula...
Faecal occult blood loss accurately predicts future detection of colorectal cancer. A prognostic model [0.03%]
粪便潜血阳性丢失量可准确预测未来患结直肠癌的风险：预后模型
Reinier G S Meester,Hilliene J van de Schootbrugge-Vandermeer,Emilie C H Breekveldt et al.
Reinier G S Meester et al.
Objectives: To examine the prognostic potential of repeated faecal haemoglobin (F-Hb) concentration measurements in faecal immunochemical test (FIT)-based screening for colorectal cancer (CRC). ...
Genetically proxied ketohexokinase function and risk of colorectal cancer: a Mendelian randomisation study [0.03%]
基于孟德尔随机化研究的遗传代理酮己糖激酶功能与结直肠癌风险的关系
Amée M Buziau,Philip J Law,Gabriella Blokland et al.
Amée M Buziau et al.
Alan N Barkun,Loren Laine,Grigorios I Leontiadis et al.
Alan N Barkun et al.
Withdrawal of the British Society of Gastroenterology IBD risk grid for COVID-19 severity [0.03%]
英国家肠病学会关于取消炎症性肠病新冠肺炎严重程度风险矩阵的通知
Charlie W Lees,Tariq Ahmad,Christopher Andrew Lamb et al.
Charlie W Lees et al.
Y90-radioembolisation in hepatocellular carcinoma induces immune responses calling for early treatment with multiple checkpoint blockers [0.03%]
钇90内照射诱导肝癌特异性免疫反应要求早期联合多种免疫检查点阻断治疗
Licia Rivoltini,Sherrie Bhoori,Chiara Camisaschi et al.
Licia Rivoltini et al.