A novel peptide protects against diet-induced obesity by suppressing appetite and modulating the gut microbiota [0.03%]
一种新型多肽通过抑制食欲和调节肠道微生物群来预防饮食诱导的肥胖
Zhanzhan Li,Bing Zhang,Ning Wang et al.
Zhanzhan Li et al.
Objective: The obesity epidemic and its metabolic complications continue to be a major global public health threat with limited effective treatments, especially drugs that can be taken orally. Peptides are a promising cla...
Autologous T cell responses to primary human colorectal cancer spheroids are enhanced by ectonucleotidase inhibition [0.03%]
自体T细胞对原代人类结直肠癌类器官的反应可通过抑制核苷酸外切酶得到增强
Julie Bonnereau,Tristan Courau,Nicolas Asesio et al.
Julie Bonnereau et al.
Objective: T cells are major effectors of the antitumoural immune response. Their activation by tumour-associated antigens can unleash their proliferation and cytotoxic functions, leading to tumour cell elimination. Howev...
British Society of Gastroenterology guidelines on the management of functional dyspepsia [0.03%]
英国胃肠病学会关于功能性消化不良管理的指南
Christopher J Black,Peter A Paine,Anurag Agrawal et al.
Christopher J Black et al.
Functional dyspepsia (FD) is a common disorder of gut-brain interaction, affecting approximately 7% of individuals in the community, with most patients managed in primary care. The last British Society of Gastroenterology (BSG) guideline fo...
Practice Guideline
Gut. 2022 Sep;71(9):1697-1723. DOI:10.1136/gutjnl-2022-327737 2022
Impact of pre-procedural testing on SARS-CoV-2 transmission to endoscopy staff [0.03%]
内镜术前检测对减少内镜从业人员SARS-CoV-2传播的影响
Alexander Hann,Sven Flemming,Stanislaus Reimer et al.
Alexander Hann et al.
Alessandro Repici,Antonio Capogreco,Marco Spadaccini et al.
Alessandro Repici et al.
Genetic variation in TERT modifies the risk of hepatocellular carcinoma in alcohol-related cirrhosis: results from a genome-wide case-control study [0.03%]
一项全基因组病例对照研究发现TERT基因变异可改变酒精性肝硬化患者肝细胞癌发病风险
Stephan Buch,Hamish Innes,Philipp Ludwig Lutz et al.
Stephan Buch et al.
Objective: Hepatocellular carcinoma (HCC) often develops in patients with alcohol-related cirrhosis at an annual risk of up to 2.5%. Some host genetic risk factors have been identified but do not account for the majority ...
Meta-Analysis
Gut. 2023 Feb;72(2):381-391. DOI:10.1136/gutjnl-2022-327196 2023
Lumen-apposing metal stents versus double-pigtail plastic stents for infected necrotising pancreatitis: more doubts than answers [0.03%]
针对感染性坏死性胰腺炎，金属桥接吻合支架与双猪尾塑料支架孰优孰劣：仍需进一步研究证实
Alberto Larghi,Antonio Facciorusso
Alberto Larghi
Autoimmune gastritis: long-term natural history in naïve Helicobacter pylori-negative patients [0.03%]
自身免疫性胃炎：未感染幽门螺杆菌患者的长期自然病程
Massimo Rugge,Ludovica Bricca,Stefano Guzzinati et al.
Massimo Rugge et al.
Objective: Autoimmune gastritis (AIG) is an immunomediated disease targeting parietal cells, eventually resulting in oxyntic-restricted atrophy. This long-term follow-up study aimed at elucidating the natural history, his...