Large-scale profile study on hepatitis B surface antigen levels in chronic hepatitis B: implications for drug development targeting functional cure [0.03%]
慢性乙型肝炎患者大规模血清学调查：针对功能性治愈的药物研发意义
Rex Wan-Hin Hui,Trevor Kwan-Hung Wu,Karen Cheuk-Ying Ho et al.
Rex Wan-Hin Hui et al.
Background: Quantitative hepatitis B surface antigen (qHBsAg) is an important biomarker in chronic hepatitis B (CHB). Objective: Establ...
Yuan Suo,Robert Thimme,Bertram Bengsch
Yuan Suo
The liver is a highly multifunctional organ that can perform many metabolic and immunological functions due to a highly complex spatially organised microarchitecture that is disturbed in many liver diseases. Recent methodological advances i...
Erica Villa
Erica Villa
Implementing discard strategies for diminutive polyps using autonomous CADx in clinical practice [0.03%]
基于自主CADx的临床实践中实施减小息肉的剔除策略
Mahsa Taghiakbari,Douglas K Rex,Heiko Pohl et al.
Mahsa Taghiakbari et al.
Targeting Aurora kinase B regulates cholesterol metabolism and enhances chemoimmunotherapy in cholangiocarcinoma [0.03%]
靶向牛磺酸受体调节胆固醇代谢并增强胆管癌的化疗免疫治疗
Furong Liu,Wei Chen,Ze Zhang et al.
Furong Liu et al.
Background: Cholangiocarcinoma (CCA) is a highly lethal malignant tumour with increasing incidence. Current therapies exhibit limited benefits, which urgently demand the identification of novel therapeutic targets. ...
Reconsidering statins in MASLD: beyond cardiovascular protection to multisystem benefit [0.03%]
重新审视MASLD中的他汀类药物：从心血管保护到多系统获益
Xiao-Dong Zhou,Vincent Wai-Sun Wong,Ming-Hua Zheng
Xiao-Dong Zhou
Thrombospondin-2 is a performant biomarker of at-risk MASH and advanced MASH fibrosis in a large multicentre European cohort [0.03%]
thrombospondin-2是MASH和晚期MASH纤维化高风险患者的高效生物标志物：一项欧洲多中心大型队列研究
Vlad Ratziu,Rambabu Surabattula,Elisabetta Bugianesi et al.
Vlad Ratziu et al.
Background: Non-invasive biomarkers with biological rationale are needed for identifying patients with progressive metabolic dysfunction-associated steatohepatitis (MASH). ...
Real-world impact of implementing lumen-apposing metal stents for pancreatic fluid collections: a nationwide Japanese study [0.03%]
日本全国范围内部置光谱支撑金属支架治疗胰腺液体积聚的现实世界影响：一项日本全国性研究
Tsuyoshi Hamada,Nobuaki Michihata,Tomotaka Saito et al.
Tsuyoshi Hamada et al.
Background: Lumen-apposing metal stents (LAMSs) are increasingly used for the endoscopic management of pancreatic fluid collections (PFCs), including walled-off necrosis (WON) and pancreatic pseudocysts (PCs). ...
Partial cure of chronic hepatitis B: potential implications for HCC surveillance? [0.03%]
慢性乙型肝炎的部分治愈会对肝癌监测产生潜在影响吗？
Wai-Kay Seto,Anna Lok
Wai-Kay Seto
Performance of the China-CLIF framework in acute-on-chronic liver failure: a multicohort study across all aetiologies [0.03%]
中国急性-on-慢性肝衰竭-China-CLIF评分体系的多队列研究（涵盖所有病因）
Jinjin Luo,Meiqian Hu,Tingting Feng et al.
Jinjin Luo et al.
Background: Acute-on-chronic liver failure (ACLF) of various aetiologies is a complex syndrome with high short-term mortality and significant global burden. ...