Real-world validation of a prognostic clinical index to predict steroid response in acute severe colitis: a single tertiary centre retrospective study [0.03%]
急性重度结肠炎对糖皮质激素反应的预后临床指标的实证验证：一项单中心回顾性研究
Vincent Bouillon,Christophe De Terwangne,Claire Liefferinckx et al.
Vincent Bouillon et al.
ISG15 deficiency in hepatic stellate cells promotes TGFβ2-induced liver fibrosis by counteracting CREB1 ISGylation [0.03%]
肝星状细胞中ISG15缺陷通过对抗CREB1-ISGylation促进TGFβ2诱导的肝纤维化
Yue Yuan,Jiaxuan Li,Dean Rao et al.
Yue Yuan et al.
Background: Interferon (IFN)-stimulated gene 15 (ISG15) is a downstream molecule of the IFN pathways central to many cellular processes. ISG15 mainly exerts its function through a post-translational modification process k...
Feng Zhang,Ying Lv,Yuzheng Zhuge et al.
Feng Zhang et al.
Artificial intelligence-tailored bowel preparation reduces laxative burden and promotes sustainable endoscopy [0.03%]
人工智能定制的肠道准备减少导泻负担并促进可持续内镜检查
Yang-Bor Lu,Si-Cun Lu,Yung-Ning Huang et al.
Yang-Bor Lu et al.
Intrahepatic donor microbiota-based metataxonomic signature detected in organ preservation solution enables prediction of short-term liver transplant outcomes [0.03%]
基于器官保存液中的供者肝脏菌群元分类学标志物预测肝移植短期预后
Fernando Lucas-Ruiz,Daniel Vidal-Correoso,Sandra V Mateo et al.
Fernando Lucas-Ruiz et al.
Background: Liver transplantation (LT) remains hampered by post-transplant complications. While gut microbiota dysbiosis has been linked to transplant outcomes, the role of the intrahepatic graft's native microbiota remai...
Clinical results of an HBV-specific T-cell receptor-T-cell therapy (SCG101) in patients with HBV-related hepatocellular carcinoma treated in an investigator-initiated, interventional trial [0.03%]
HBV特异性T细胞受体-T细胞治疗药物(SCG101)在乙肝相关肝癌患者中临床研究结果(一项由 investigators发起干预式试验)
Xiang&#x;an Wu,Dongmei Quan,Wei Li et al.
Xiang&#x;an Wu et al.
Background: SCG101 is an autologous T-cell therapy specifically targeting hepatitis B virus (HBV) using a natural, high-affinity T-cell receptor that is stably expressed. ...
Mucosal transcriptomic landscape along the small and large intestines in individuals with and without type 2 diabetes [0.03%]
有无2型糖尿病的个体的小肠和大肠黏膜转录组特征
Hannah Gilliam-Vigh,Anne Marie Ellegaard,Martin Rønn Madsen et al.
Hannah Gilliam-Vigh et al.
Background: A detailed mapping of functional differences among intestinal regions in healthy individuals remains incomplete. Identifying regional alterations in individuals with type 2 diabetes (T2D) could enhance our und...
Global prevalence and gastrointestinal symptom burden of individuals with a history of cholecystectomy [0.03%]
胆囊切除术患者的全球流行率和胃肠症状负担
Bo Konings,Lukas Michaja Balsiger,Johann Pall Hreinsson et al.
Bo Konings et al.
Background: Cholecystectomy is commonly performed globally, and many patients with disorders of gut-brain interaction (DGBI) report that their symptoms have either preceded or developed following cholecystectomy. ...
Role of CNNM4 in the progression of cholangiocarcinoma: implications for ferroptosis and therapeutic potential [0.03%]
CNNM4在胆管癌进展中的作用：铁死亡及治疗潜力的启示
Maria Mercado-Gómez,Naroa Goikoetxea-Usandizaga,Alvaro Eguileor Giné et al.
Maria Mercado-Gómez et al.
Background and objective: Cholangiocarcinoma (CCA) is a heterogeneous neoplasm of the biliary epithelium that easily infiltrates, metastasises and recurs. Magnesium disbalance is a hallmark of CCA, with the magnesium tran...