LECT2-PHB2 axis: a new mechanistic insight and therapeutic opportunity in alcohol-associated hepatitis [0.03%]
LECT2-PHB2轴在酒精性肝炎发病机制及治疗中的新认识与机遇
Hui Li,Meiyi Song,Phillip B Hylemon et al.
Hui Li et al.
Can transperineal ultrasound replace endoscopic ultrasound in staging distal ulcerative colitis? [0.03%]
经直肠超声能否替代内镜超声用于溃疡性结肠炎的分期？
Partha Pal,Mohammad Abdul Mateen,Anuradha Sekaran et al.
Partha Pal et al.
Prevention of rebleeding after primary haemostasis using haemostatic powder in non-variceal upper gastrointestinal bleeding: a multicentre randomised controlled trial [0.03%]
非静脉曲张性上消化道出血止血后使用止血粉预防再出血：多中心随机对照试验
Jongbeom Shin,Boram Cha,Jitaek Hong et al.
Jongbeom Shin et al.
Background: Non-variceal upper gastrointestinal bleeding (NVUGIB) remains a major cause of morbidity and mortality. Rebleeding rates following endoscopic treatment can reach up to 25% within 72 hours in patients with high...
Large language models for detecting colorectal polyps in endoscopic images [0.03%]
基于内窥镜图像的大语义模型结直肠息肉检测技术
Luca Carlini,Davide Massimi,Yuichi Mori et al.
Luca Carlini et al.
Activation of RAS/MEK/ERK signalling drives biliary differentiation in primary liver cancer [0.03%]
RAS/MEK/ERK信号通路的激活驱动原发性肝癌胆管分化
Thomas Rösner,Carina Rupp,Christian Lechler et al.
Thomas Rösner et al.
Background: RAS mutations are frequently observed in human cholangiocarcinoma (CCA), while they are relatively rare in hepatocellular carcinoma (HCC). The role of RAS-dependent signalling pathways in CCA development is cu...
Multicentre RCT of a self-assembling haemostatic gel to prevent delayed bleeding following EMR-an underpowered sample size calculation [0.03%]
一项自我组装止血凝胶预防内镜黏膜下剥离术后迟发性出血的多中心随机对照试验-过低的样本量估算
Eduardo Albéniz,Sheyla Montori
Eduardo Albéniz
Beneficial infections of the enterovirus genus in patients with liver cancer [0.03%]
肝癌患者中的肠病毒属益生感染现象
Lichun Ma,Man Hsin Hung,Farid Rashidi Mehrabadi et al.
Lichun Ma et al.
Background: Hepatocellular carcinoma (HCC) is a significant global cancer burden, with rising incidence and lacking a unified prevention strategy due to complex aetiologies. Viral exposures may shape host immunity via spe...
British Society of Gastroenterology guidelines on colorectal surveillance in inflammatory bowel disease [0.03%]
英国胃肠病学会炎症性肠病结直肠癌筛查指南
James Edward East,Morris Gordon,Gaurav Bhaskar Nigam et al.
James Edward East et al.
Patients with inflammatory bowel disease (IBD) remain at increased risk for colorectal cancer and death from colorectal cancer compared with the general population despite improvements in inflammation control with advanced therapies, colono...
BSG/ACPGBI guidance on the management of colorectal polyps in patients with limited life expectancy [0.03%]
BSG/ACPGBI关于有限预期生存期患者结直肠息肉管理的指导意见
Matthew D Rutter,Ravi Ranjan,Clare Westwood et al.
Matthew D Rutter et al.
Background: Determining optimal management of colorectal polyps in patients with limited life expectancy of under 10 years can be difficult, due to challenges balancing an uncertain natural history of polyp progression to...
Systemic treatment in patients with hepatocellular carcinoma and advanced liver dysfunction [0.03%]
肝细胞癌伴严重肝功能不全患者的全身治疗
Matthias Pinter,Claudia A M Fulgenzi,David J Pinato et al.
Matthias Pinter et al.
Systemic therapy represents the standard of care treatment for patients with advanced hepatocellular carcinoma (HCC). Given the increased risk of death from cirrhosis-related complications in patients with advanced liver dysfunction, pivota...