Normal pressure hydrocephalus and cognitive impairment: The gait phenotype matters too [0.03%]
正常压力性脑积水和认知障碍:步态表型也很重要
Eric Morel,Alma Lingenberg,Stéphane Armand et al.
Eric Morel et al.
Background and purpose: Idiopathic normal pressure hydrocephalus (iNPH) is a chronic neurological disease resulting in progressive gait and cognitive disorders. We investigated whether the gait phenotype is associated wit...
Structural correlations between brain magnetic resonance image-derived phenotypes and retinal neuroanatomy [0.03%]
基于脑磁共振影像表型与视网膜神经解剖结构的相关性研究
Zihan Sun,Bing Zhang,Stephen Smith et al.
Zihan Sun et al.
Background and purpose: The eye is a well-established model of brain structure and function, yet region-specific structural correlations between the retina and the brain remain underexplored. Therefore, we aim to explore ...
Use of the combination of spirometry, arterial blood gas analysis and overnight oximetry to predict the outcomes of patients affected by motor neuron disease: The Milan-Torin respiratory score (Mi-To-RS) [0.03%]
预测肌萎缩侧索硬化患者呼吸功能下降的米兰-都灵综合评分(Mi-To-RS)
Paride Schito,Umberto Manera,Tommaso Russo et al.
Paride Schito et al.
Background and purpose: The use of multiple tests, including spirometry, arterial blood gas (ABG) analysis and overnight oximetry (OvOx), is highly recommended to monitor the respiratory function of patients with motor ne...
Overcoming therapeutic challenges: Successful management of a supposedly triple seronegative, refractory generalized myasthenia gravis patient with efgartigimod [0.03%]
克服治疗挑战:成功管理一名疑似三抗体阴性的重症肌无力患者(采用efgartigimod疗法)
Benedetta Sorrenti,Christian Laurini,Luca Bosco et al.
Benedetta Sorrenti et al.
Background and purpose: This study was undertaken to highlight neonatal Fc receptor inhibition (efgartigimod) as a valuable therapeutic option for patients with refractory seronegative myasthenia gravis (MG) and to emphas...
Glucagonlike peptide-1 receptor agonists versus dipeptidyl peptidase-4 inhibitors in ischemic strokes with diabetes 2 [0.03%]
糖尿病缺血性卒中患者中GLP-1受体激动剂与DPP-4抑制剂的对照研究
Sidsel Hastrup,Jakob Nebeling Hedegaard,Grethe Andersen et al.
Sidsel Hastrup et al.
Background and purpose: Cardiovascular outcome trials demonstrate that glucagonlike peptide-1 receptor agonists (GLP-1RAs) reduce the risk of major adverse cardiovascular events in patients with type 2 diabetes (T2D), whe...
Comparative Study
European journal of neurology. 2024 Aug;31(8):e16329. DOI:10.1111/ene.16329 2024
Quantifying neurodegeneration of the cervical cord and brain in degenerative cervical myelopathy: A multicentre study using quantitative magnetic resonance imaging [0.03%]
定量磁共振影像多中心研究评估脊髓型颈椎病患者的颈髓和大脑神经退行性变量化指标
Patrick Freund,Viveka Boller,Tim M Emmenegger et al.
Patrick Freund et al.
Background and purpose: Simultaneous assessment of neurodegeneration in both the cervical cord and brain across multiple centres can enhance the effectiveness of clinical trials. Thus, this study aims to simultaneously as...
Multicenter Study
European journal of neurology. 2024 Jul;31(7):e16297. DOI:10.1111/ene.16297 2024
Causal association between circulating inflammatory cytokines and intracranial aneurysm and subarachnoid hemorrhage [0.03%]
循环炎症细胞因子与颅内动脉瘤及蛛网膜下腔出血的因果关系
Qiang He,Wenjing Wang,Yang Xiong et al.
Qiang He et al.
Background and purpose: The causal association between inflammatory cytokines and the development of intracranial aneurysm (IA), unruptured IA (uIA) and subarachnoid hemorrhage (SAH) lacks clarity. ...
Perspectives on the diagnosis and management of functional cognitive disorder: An international Delphi study [0.03%]
功能性认知障碍的诊断和管理观点:一项国际德尔菲研究
Verónica Cabreira,Jane Alty,Sonja Antic et al.
Verónica Cabreira et al.
Background: Current proposed criteria for functional cognitive disorder (FCD) have not been externally validated. We sought to analyse the current perspectives of cognitive specialists in the diagnosis and management of F...
Serum neurofilament light chain and glial fibrillary acidic protein for predicting response to apheresis in steroid-refractory multiple sclerosis relapses [0.03%]
用于预测难治性类固醇多发性硬化复发患者血浆神经丝轻链和胶质纤维酸性蛋白对血浆置换疗法的反应能力
Ioannis Vardakas,Johannes Dorst,André Huss et al.
Ioannis Vardakas et al.
Background and purpose: The predictive value of serum neurofilament light chain (sNfL) and serum glial fibrillary acidic protein (sGFAP) for apheresis outcome in steroid-refractory multiple sclerosis (MS) relapse has not ...
Clinical Trial
European journal of neurology. 2024 Aug;31(8):e16323. DOI:10.1111/ene.16323 2024
Ceroid lipofuscinosis type 2 disease: Effective presymptomatic therapy-Oldest case of a presymptomatic enzyme therapy [0.03%]
ceroid脂质沉积病2型疾病:有效的前期治疗-酶前期治疗的最早病例报告
Delphine Breuillard,Lisa Ouss,Marie Thérèse Le Normand et al.
Delphine Breuillard et al.
Neuronal ceroid lipofuscinosis type 2 (CLN2) disease is a rare, lysosomal storage disorder that causes pediatric onset neurodegenerative disease. It is characterized by mutations in the TPP1 gene. Symptoms begin between 2 and 4 years of age...
Case Reports
European journal of neurology. 2024 May 1:e16324. DOI:10.1111/ene.16324 2024