A Novel 3D Semi-Automated Full Quantification Technique for Detection of Intraneural Phospho-α-Synuclein in Skin Biopsies [0.03%]
一种新颖的三维半自动完全定量技术用于检测皮肤活检标本中神经内磷酸化-α-突触核蛋白
Sophia Lonczewski,Verian Bader,Louisa Ortmann et al.
Sophia Lonczewski et al.
Background: Parkinson's disease (PD) and multiple system atrophy (MSA) are synucleinopathies marked by α-synuclein aggregation, while progressive supranuclear palsy (PSP) is a tauopathy. Clinical overlap between these di...
Response to Letter to Editor: Headache After Sealing of Cerebrospinal Fluid Leaks in Patients With Spontaneous Intracranial Hypotension [0.03%]
自发性颅内低血压患者封闭脑脊液漏后头痛的回复（来信）
Adrian Scutelnic,Nedelina Slavova,Eric Morel et al.
Adrian Scutelnic et al.
Carmen Jacob,Thomas E Williams,Charlotte M Stuart et al.
Carmen Jacob et al.
Background: Aberrant iron homeostasis is increasingly recognized as a key pathological feature in progressive multiple sclerosis (MS). Although the source of excess brain iron remains unclear, haemoglobin is one possible ...
Multicenter Study
European journal of neurology. 2026 Apr;33(4):e70595. DOI:10.1111/ene.70595 2026
Kappa Free Light Chains Reflect Treatment Response and Progression Independent of Focal Inflammation in Multiple Sclerosis [0.03%]
κ型自由轻链反映治疗反应和独立于多发性硬化病灶炎症的疾病进展
Igal Rosenstein,Markus Axelsson,Magnus Johnsson et al.
Igal Rosenstein et al.
Background: Cerebrospinal fluid (CSF) kappa free light chains (KFLC) is a sensitive marker of intrathecal immunoglobulin synthesis and is incorporated into the 2024 McDonald criteria for multiple sclerosis (MS). How disea...
Assessment of Mitochondrial DNA Copy Number in Progressive Supranuclear Palsy Patients: Evidence From a Pilot Study [0.03%]
进展性核上性麻痹患者线粒体DNA拷贝数的评估：来自一项初步研究的证据
Luigi Citrigno,Annamaria Cerantonio,Monica Gagliardi et al.
Luigi Citrigno et al.
Background: Progressive supranuclear palsy (PSP) is a rare neurodegenerative tauopathy characterized by early postural instability and vertical gaze palsy. Mitochondrial dysfunctions have been increasingly implicated in t...
Clinical Features and Prognosis of SEPTIN9-Related Hereditary Neuralgic Amyotrophy [0.03%]
与SEPITN9相关遗传性神经痛性肌萎缩的临床特征及预后
Julian Theuriet,Isabelle Quadrio,Frédéric Fer et al.
Julian Theuriet et al.
Background: Neuralgic amyotrophy (NA) causes acute episodes of neuropathic pain in the upper limbs, followed by weakness and atrophy. NA can be idiopathic (INA) or hereditary (HNA). The SEPTIN9 gene has been linked to HNA...
Multicenter Study
European journal of neurology. 2026 Apr;33(4):e70603. DOI:10.1111/ene.70603 2026
Complement Inhibition Therapy in Myasthenic Crisis-A Multicentre Retrospective Analysis of 17 Cases From Germany [0.03%]
德国多中心重症肌无力危象补体抑制疗法的回顾性分析（17例）
Lea Gerischer,Maike Stein,Alice Schneider et al.
Lea Gerischer et al.
Introduction: Generalized myasthenia gravis (gMG) may progress to life-threatening myasthenic crises (MC) requiring mechanical ventilation. Standard therapy includes intravenous immunoglobulins (IVIg), plasmapheresis (PLE...
Multicenter Study
European journal of neurology. 2026 Apr;33(4):e70596. DOI:10.1111/ene.70596 2026
Headache After Coil Embolization for Unruptured Intracranial Aneurysms (Non-Stent-Assisted Versus Stent-Assisted): A Prospective Comparative Cohort Study [0.03%]
颅内未破裂动脉瘤栓塞术(非支架辅助与支架辅助)后头痛：前瞻性队列研究
Seung Pil Ban,O-Ki Kwon,Young Deok Kim et al.
Seung Pil Ban et al.
Background: The worsening of headaches or the occurrence of new headaches can occur after coil embolization. Although the frequency of headaches is reported to be greater when a stent is used, this phenomenon is poorly un...
Comparative Study
European journal of neurology. 2026 Apr;33(4):e70598. DOI:10.1111/ene.70598 2026
The Role of Digital Tools and Their Implementation Within Patient Care Pathways for Rare Brain Disorders: The Case of Phenylketonuria [0.03%]
罕见脑障碍患者诊疗途径中数字工具的作用及其实施情况——苯酮尿症为例
Sara Cannizzo,Vinciane Quoidbach,Bernadette Sheehan-Gilroy et al.
Sara Cannizzo et al.
Introduction: The COVID-19 pandemic accelerated the adoption of digital health solutions in healthcare. Phenylketonuria (PKU) is a rare condition requiring chronic management and frequent assessments, making it a useful m...
Migraine Patients Treated With Erenumab and the Risk of Hypertension: A Registry-Based Real-World Study [0.03%]
偏头痛患者使用艾尔建治疗与高血压风险的关系：基于登记数据库的真实世界研究
Christian Lampl,Reem Suliman,Viktoria Tischler-Strasser et al.
Christian Lampl et al.
Background: Recent post-marketing studies have indicated a possible association between anti-CGRP receptor monoclonal antibodies (anti-CGRP-mAbs) used for migraine prophylaxis and an increased risk of hypertension (HT). ...