Cerebrospinal fluid and blood neurofilament light chain levels in amyotrophic lateral sclerosis and frontotemporal degeneration: A meta-analysis [0.03%]
遗传性肌萎缩侧索硬化症和额颞叶变性的脑脊液和血液神经丝轻链水平的meta分析研究
Federico Verde,Sara Licaj,Davide Soranna et al.
Federico Verde et al.
Background and purpose: Neurofilament light chain (NFL) has been shown to be increased in amyotrophic lateral sclerosis (ALS) and, to a lesser extent, in frontotemporal dementia (FTD). A meta-analysis of NFL in ALS and FT...
Sex- and age-related shift of relapse phenotypes in a cohort of relapsing multiple sclerosis patients: Post hoc analysis from the OPERA phase 3 trials [0.03%]
一项在复发性多发性硬化症患者队列中观察复发表型的性别及年龄相关变化的事后分析：来自OPERA三期临床试验的结果
A Leon Betancourt,Robert Hoepner,Helly Hammer et al.
A Leon Betancourt et al.
Background and purpose: Relapse presentation in relapsing multiple sclerosis (RMS) differs between sexes, leading to differential outcomes. An influence of age seems likely but is less well investigated separately for wom...
Thrombectomy improves functional independence in severe basilar artery occlusion with favorable collateral circulation [0.03%]
良好的侧支循环可改善严重基底动脉闭塞的功能独立性 thrombectomy疗法的作用
Cong Luo,Chunrong Tao,Rui Li et al.
Cong Luo et al.
Background and purpose: This study aimed to investigate the effect of collateral circulation on the outcomes of thrombectomy versus medical management alone in basilar artery occlusion (BAO) patients with varying stroke s...
Neurofilament light chain and profilin-1 dynamics in 30 spinal muscular atrophy type 3 patients treated with nusinersen [0.03%]
nusinersen治疗的30例脊髓性肌萎缩症3型患者的神经丝轻链和肌动蛋白结合蛋白profilin-1动态变化
G Musso,L Bello,G Capece et al.
G Musso et al.
Background and purpose: The aim was to investigate whether neurofilament light chain (NfL) and profilin-1 (PFN-1) might qualify as surrogate disease and treatment-response biomarkers by correlating their concentrations dy...
Imbalanced optimal feedback motor control system in spinocerebellar ataxia type 3 [0.03%]
脊髓小脑共济失调3型中不平衡的最佳反馈电机控制系统
Leinian Li,Hui Chen,LiHua Deng et al.
Leinian Li et al.
Background and purpose: Human motor planning and control depend highly on optimal feedback control systems, such as the neocortex-cerebellum circuit. Here, diffusion tensor imaging was used to verify the disruption of the...
Song Guo,Sarah Louise Christensen,Mohammad Al-Mahdi Al-Karagholi et al.
Song Guo et al.
Objective: This review will explore the categorization of migraine-provoking molecules, their cellular actions, site of action and potential drug targets based on the migraine cascade model. ...
Jinhong Wu,Lishun Liu,Zena Huang et al.
Jinhong Wu et al.
Background and purpose: Hypertension significantly contributes to stroke. Previous research has indicated a connection between daytime napping and stroke. Research on the connection between daytime napping duration and fi...