Explainable Artificial Intelligence to Predict Neurocognitive Disorder Progression in Multiple Sclerosis Using MRI and Clinical Data [0.03%]
基于MRI和临床数据预测多发性硬化认知障碍进展的可解释人工智能方法
Loredana Storelli,Damiano Mistri,Alice Mastropasqua et al.
Loredana Storelli et al.
Background: Cognitive impairment is common in multiple sclerosis (MS), yet the application of diagnostic frameworks of Neurocognitive Disorders (NCDs) is limited. Additionally, the integration of multimodal data for predi...
Identification and Functional Characterization of Novel and Recurrent NTRK1 Variants in Chinese Families With Congenital Insensitivity to Pain With Anhidrosis: A Combined Clinical, Genetic, and Functional Study [0.03%]
中国人Congenital Insensitivity to Pain With Anhidrosis家系中NTRK1新发及复发变异的识别与功能表征：一项临床、遗传和功能研究联合分析
Yaqiong Ren,Yue Cao,Fangfang Cheng et al.
Yaqiong Ren et al.
Background: Congenital insensitivity to pain with anhidrosis (CIPA) is an autosomal recessive disorder caused by variants in the NTRK1 gene (encoding TrkA). The identification and functional analysis of these variants are...
The Relevance of Crystal Clear and Unclear Days to Evaluate Residual Interictal Burden in Patients With Migraine Treated With CGRP Monoclonal Antibodies [0.03%]
结晶清晰和不清晰的日子与评估CGRP单克隆抗体治疗偏头痛患者的残留间歇期负担的相关性
Marcello Silvestro,Ilaria Orologio,Raffaele Ornello et al.
Marcello Silvestro et al.
Background: Although treatment goals in migraine prevention have moved beyond the benchmark of a 50% reduction in monthly attacks, residual disease burden is still evaluated based on residual headache frequency. However, ...
Paul Philipp Kastner,Pia Lena Niederau,Georgios Pantazis et al.
Paul Philipp Kastner et al.
Background: Subacute oculomotor dysfunction encompasses a broad differential diagnosis, including autoimmune, infectious, vascular, and neoplastic etiologies. Primary skull base diffuse large B-cell lymphoma (DLBCL) is a ...
Characteristics of Patients with Myasthenia Gravis in the French Rare Disease Registry [0.03%]
法国罕见病注册中心重症肌无力患者的特点
Jean-Philippe Camdessanche,Andoni Echaniz-Laguna,Guilhem Solé et al.
Jean-Philippe Camdessanche et al.
Background: The French National Rare Diseases Registry (BNDMR) was established in 2007 to ensure access to optimal care standards for all patients with rare diseases in dedicated reference centres. The objective of this r...
Mood and Age Predict Cognitive Complaints in Memory Clinic Patients: A Machine-Learning and Linear Modeling Approach [0.03%]
情绪和年龄预测记忆诊所患者的认知抱怨：机器学习和线性模型方法
Florian W Sander,Marie Pittet,Valeria Manera et al.
Florian W Sander et al.
Introduction: Cognitive complaints are often considered early indicators of Alzheimer's disease (AD) and commonly lead to memory clinic consultations. Prior studies suggest stronger associations between cognitive complain...
Multicenter Study
European journal of neurology. 2026 Apr;33(4):e70583. DOI:10.1111/ene.70583 2026
Understanding Lifestyle Dissonance: A Neurobiological Narrative to Strengthen Preventive Health Behavior [0.03%]
理解生活方式失调：一个神经生物学的故事，以增强预防性健康行为
Daniela Berg,Mareike Krause,Eva Schaeffer et al.
Daniela Berg et al.
Background: Noncommunicable diseases are the leading cause of death and disability worldwide, although many of their detrimental health effects can be prevented by lifestyle changes. Despite growing public and individual ...
Antipsychotics and Their Association With Long-Term Outcomes in Young Ischemic Stroke Patients [0.03%]
抗精神病药物与青年缺血性卒中患者长期结局的关系
Jenna Broman,Karoliina Aarnio,Hanna Granroth-Wilding et al.
Jenna Broman et al.
Background: Psychotic disorders and use of antipsychotics prior to or after ischemic stroke (IS) may be associated with poor outcomes. However, data on antipsychotic use in young IS patients are limited. We aimed to chara...
Assessing Optic Nerve Involvement in Multiple Sclerosis Using Optical Coherence Tomography and Magnetic Resonance Imaging [0.03%]
应用光学 coherence 拍摄和磁共振成像评估多发性硬化症的视神经受损情况
Gualco Alessandro,Boffa Giacomo,Razzetta Chiara et al.
Gualco Alessandro et al.
Background: Optic nerve involvement in Multiple Sclerosis (MS) can be detected with Optical Coherence Tomography (OCT) based on intereye difference (IED). We aimed to assess optic nerve involvement in a large real-world M...
Diagnostic Criteria and Management of MELAS and Stroke-Like Episodes: Consensus-Based Statements [0.03%]
MELAS和卒中样发作的诊断标准与处理建议：共识声明
Michelangelo Mancuso,Marcello Bellusci,Valerio Carelli et al.
Michelangelo Mancuso et al.
Background and purpose: Mitochondrial Encephalomyopathy, Lactic acidosis and Stroke-like episodes (MELAS) is a rare multisystem mitochondrial disorder with clinical heterogeneity. Diagnostic criteria and management strate...