Paramagnetic rim lesions are associated with inner retinal layer thinning and progression independent of relapse activity in multiple sclerosis [0.03%]
多发性硬化症中与复发病变无关的顺磁性边缘病变与视网膜内层变薄和进展有关
Nik Krajnc,Leo Hofer,Fabian Föttinger et al.
Nik Krajnc et al.
Background and purpose: Paramagnetic rim lesions (PRLs) are chronic active lesions associated with a severe disease course in multiple sclerosis (MS). This study was undertaken to investigate an association between retina...
Brain neurovascular coupling in amyotrophic lateral sclerosis: Correlations with disease progression and cognitive impairment [0.03%]
渐冻症患者脑神经血管耦合与疾病进展及认知障碍之间的相关性研究
Francesca Trojsi,Antonietta Canna,Minoo Sharbafshaaer et al.
Francesca Trojsi et al.
Background and purpose: 'Neurovascular coupling' (NVC) alterations, assessing the interplay between local cerebral perfusion and neural activity within a given brain region or network, may reflect neurovascular unit impai...
Small fiber neuropathy associated with COVID-19 infection and vaccination: A prospective case-control study [0.03%]
与COVID-19感染和疫苗接种相关的小纤维神经病：一项前瞻性病例对照研究
Vincenzo Donadio,Alex Incensi,ALessandro Furia et al.
Vincenzo Donadio et al.
Background: Small fiber neuropathy (SFN) after both COVID-19 infection or vaccination has been reported in sporadic cases, but a detailed description and comparison are missing. We aimed to screen a large cohort of patien...
Mobile stroke units services in Germany: A cost-effectiveness modeling perspective on catchment zones, operating modes, and staffing [0.03%]
德国移动卒中单元服务：从成本效益模型角度审视服务区、运营模式和人员配置
Johann S Rink,Kristina Szabo,Carolin Hoyer et al.
Johann S Rink et al.
Background and purpose: Investigating the cost-effectiveness of future mobile stroke unit (MSU) services with respect to local idiosyncrasies is essential for enabling large-scale implementation of MSU services. The aim o...
Prolonged use of chlormadinone acetate and risk of intracranial meningioma: A population-based cohort study [0.03%]
醋酸氯米芬长期使用与颅内脑膜瘤风险的关系：基于人群的队列研究
Noémie Roland,Pierre Nguyen,Anke Neumann et al.
Noémie Roland et al.
Background and purpose: Chlormadinone acetate (CMA) is a synthetic progestin for which cases of intracranial meningioma have been reported following prolonged exposure. ...
Observational Study
European journal of neurology. 2025 Jan;32(1):e16505. DOI:10.1111/ene.16505 2025
Mild cognitive impairment and early Alzheimer's disease eligibility for disease modification therapies in a tertiary centre for cognitive disorders: A simultaneous real-word study on aducanumab and lecanemab [0.03%]
第三级认知障碍中心的轻度认知障碍和早期阿尔茨海默病患者对疾病修饰疗法的适用性：同时进行的实际世界研究——针对阿杜那单抗和乐健单抗
G Logroscino,D Urso,V Gnoni et al.
G Logroscino et al.
Background and purpose: The Food and Drug Administration approved two disease-modifying treatments (DMTs) for Alzheimer's disease (AD), aducanumab and lecanemab, with limited clinical impact but significant biomarker chan...
Understanding Parkinson disease in Spain: Genetic and clinical insights [0.03%]
西班牙的帕金森病：遗传学和临床研究的新见解
Pilar Gómez-Garre,Miguel Martín-Bórnez,Laura Muñoz-Delgado et al.
Pilar Gómez-Garre et al.
Background and purpose: Parkinson disease (PD) is a complex and heterogeneous neurodegenerative disorder with a broad spectrum of clinical manifestations, determined by a complex interplay of environmental and genetic fac...
Midline sacral meningeal cysts: Neurophysiology abnormalities and their correlation with pelvic sensory and visceral symptoms [0.03%]
中线骶骨脑膜囊肿：神经生理异常及其与盆腔感觉和内脏症状的相关性
Ivan Cabrilo,Claire Hentzen,Prasad Malladi et al.
Ivan Cabrilo et al.
Background and purpose: Midline sacral meningeal cysts (MSMCs) are cerebrospinal fluid-filled dural diverticula. Although widely considered asymptomatic, cases involving voiding difficulties or pain have been reported. Th...
Tracking myasthenia gravis severity over time: Insights from the French health insurance claims database [0.03%]
随时间追踪重症肌无力的严重程度：来自法国健康保险索赔数据库的见解
Shahram Attarian,Jean-Philippe Camdessanché,Andoni Echaniz-Laguna et al.
Shahram Attarian et al.
Background and purpose: Few data are available on the course of myasthenia gravis (MG) regarding disease severity and stability over time in real-world settings. This study used the French National Health Insurance Databa...
Cerebrospinal fluid red blood cells and total protein are associated with clinical outcome in spontaneous subarachnoid hemorrhage [0.03%]
自发性蛛网膜下腔出血的脑脊液红细胞和总蛋白与临床预后有关
Klaus Berek,Anna Lindner,Philipp Kindl et al.
Klaus Berek et al.
Background and purpose: Prognostication in patients with spontaneous subarachnoid hemorrhage (SAH) can be challenging. The aim of this study was to assess whether cerebrospinal fluid (CSF) red blood cell (RBC) count and t...
Observational Study
European journal of neurology. 2025 Jan;32(1):e16456. DOI:10.1111/ene.16456 2025