Switching from natalizumab to antiCD20 monoclonal antibodies: Short transition interval is associated with improved outcome [0.03%]
从natalizumab切换到抗CD20单克隆抗体:短期过渡时间与较好的临床结局相关
Gabriel Bsteh,Robert Hoepner,Jonathan A Gernert et al.
Gabriel Bsteh et al.
Objective: To investigate the impact of transition interval length when switching from natalizumab (NTZ) to anti-CD20 monoclonal antibodies (antiCD20) on recurrent disease activity and safety in relapsing multiple scleros...
Assessment of the available evidence for the use of 7-Tesla (T) magnetic resonance imaging (MRI) in neurological and musculoskeletal disorders, with comparison to 3-T and 1.5-T MRI: A systematic scoping review [0.03%]
系统综述:7特斯拉磁共振成像在神经和肌肉骨骼疾病中的应用证据评估(与3特斯拉及1.5特斯拉磁共振对比)
Piotr Radojewski,Gian Franco Piredda,Gabriele Bonanno et al.
Piotr Radojewski et al.
Background: Ultra-high-field magnetic resonance imaging (MRI) at a field strength of 7 Tesla (T) has marked a significant milestone in diagnostic imaging since it was approved for clinical use in 2017. Despite the potenti...
Comparative Study
European journal of neurology. 2025 Jan;32(1):e16557. DOI:10.1111/ene.16557 2025
Spontaneous intracranial hypotension - Neurological symptoms, diagnosis, and outcome [0.03%]
自发性颅内低压的神经症状、诊断和预后
Sebastian Worsaae Dalby,Emil Andonov Smilkov,Sofia Gaspar Santos et al.
Sebastian Worsaae Dalby et al.
Background: Spontaneous intracranial hypotension (SIH) is a rare secondary headache disorder caused by spinal leakage of cerebrospinal fluid. Specialized treatment of SIH consists of epidural blood patches (EBPs), fibrin ...
Sex-related differences in amyotrophic lateral sclerosis: A 2-[18F]FDG-PET study [0.03%]
ALS的性激素差异的2-[18F]FDG-PET研究
Antonio Canosa,Alessio Martino,Umberto Manera et al.
Antonio Canosa et al.
Purpose: We investigated sex-related brain metabolic differences in Amyotrophic Lateral Sclerosis (ALS) and healthy controls (HC). Methods: ...
Determinants of long-term disability in chronic inflammatory demyelinating polyradiculoneuropathy: A multicenter Korea/UK study of 144 patients [0.03%]
慢性炎症性脱髓鞘多发性神经病长期残疾的决定因素:一项韩国和英国多中心研究(144例患者)
Young Gi Min,Jaehyun Jeon,Sung-Min Kim et al.
Young Gi Min et al.
Background: Despite standard-of-care treatment, therapeutic outcomes in chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) are often incomplete. We aimed to evaluate the impact of clinical and therapeutic fa...
Multicenter Study
European journal of neurology. 2025 Jan;32(1):e16575. DOI:10.1111/ene.16575 2025
Croplands proximity is associated with amyotrophic lateral sclerosis incidence and age at onset [0.03%]
农作物种植与肌萎缩侧索硬化症的发病率和发病年龄的关系
Umberto Manera,Stefano Callegaro,Antonio Canosa et al.
Umberto Manera et al.
Background: Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease resulting from an intricate interplay between genetics and environmental factors. Many studies have explored living in rural areas as a possib...
A common marker of affect recognition dysfunction in the FTD spectrum of disorders [0.03%]
额叶颞叶痴呆谱系障碍情感识别功能损害的共通标志
Elisa Canu,Veronica Castelnovo,Edoardo Nicolò Aiello et al.
Elisa Canu et al.
Background: Poor affect recognition is an early sign of frontotemporal dementia (FTD). Here, we applied the abbreviated version of the Comprehensive Affect Testing System (CATS-A) battery to Italian FTD cases and healthy ...
Levodopa-entacapone-carbidopa intestinal gel: Data from the Swedish national registry for Parkinson's disease [0.03%]
左旋多巴-恩他卡朋-卡比多巴肠溶凝胶:来自瑞典帕金森病国家登记的数据
Mezin Öthman,Filip Bergquist,Per Odin et al.
Mezin Öthman et al.
Background: Levodopa-entacapone-carbidopa intestinal gel (LECIG) was introduced on the Swedish market in 2019. The therapy is aimed at patients with Parkinson's disease (PD) with fluctuations and dyskinesias. Long-term ef...
Anel Karisik,Kurt Moelgg,Lucie Buergi et al.
Anel Karisik et al.
Background: Post-stroke dysphagia is known to have a pronounced effect on mortality and quality of life of stroke patients. Here, we investigate whether this extends to post-stroke fatigue, a major contributor to morbidit...
Persistent symptoms, exacerbations and drug side effects despite treatment in myasthenia gravis [0.03%]
重症肌无力患者治疗后的持续症状、加重和药物副作用
David Reyes-Leiva,Álvaro Carbayo,Ana Vesperinas-Castro et al.
David Reyes-Leiva et al.
Background: Generalized myasthenia gravis (gMG) is characterized by fluctuating muscle weakness. Exacerbation frequency, adverse events (AEs) related to immunosuppressant therapy and healthcare resource utilization (HCRU)...