Video-Oculographic Saccadic Fatigability Distinguishes Myasthenia Gravis From Unilateral Ocular Motor Cranial Nerve Palsy in Diplopia: A Prospective Diagnostic Study [0.03%]
视频眼动记录扫视疲劳在复视中区分肌无力和单侧颅神经麻痹：一项前瞻性诊断研究
Juhee Chae,Min-Woo Lee,Sun-Young Oh
Juhee Chae
Objective: To determine whether repetition-based saccadic fatigability measured with three-dimensional video-oculography (VOG) distinguishes myasthenia gravis (MG) from unilateral ocular motor cranial nerve palsy (CNP) in...
Effect of Concomitant Medications on Adverse Event Frequency, Severity, and Time to Resolution in a Cenobamate Open-Label Trial [0.03%]
卡马布特开放标签试验中伴随用药对不良事件发生率、严重程度和持续时间的影响
Bernhard J Steinhoff,Antonio Gil-Nagel,Elena Alvarez-Baron et al.
Bernhard J Steinhoff et al.
Background and purpose: Polytherapy in epilepsy is associated with a higher risk of adverse events, poorer adherence, and impaired quality of life. Thus, reducing concomitant antiseizure medications (ASMs) and/or using a ...
Accelerating Research on Brain Aging: Enabling Brain Imaging Data Sharing in the Open Science Landscape [0.03%]
加速脑老化研究：在开放科学背景下实现脑影像数据共享
Kathrin Giehl,Thilo van Eimeren
Kathrin Giehl
The global burden of age-associated diseases continues to grow. In particular, the accelerating impact of neurodegenerative diseases on individuals, communities and societies necessitates more effective approaches to diagnosis, prognosis an...
Association of Serum hs-CRP and TNF-α With Therapeutic Response to Erenumab for Migraine Prevention: A Registry for Migraine (REFORM) Study [0.03%]
血清hs-CRP和TNF-α与偏头痛预防用艾尔建单抗治疗反应的相关性：偏头痛登记处研究(REFORM)
William K Karlsson,Rune H Christensen,Haidar M Al-Khazali et al.
William K Karlsson et al.
Background: Experimental studies show inflammatory cytokines can modulate calcitonin gene-related peptide (CGRP) signaling, suggesting systemic inflammatory markers might reflect biological processes relevant to anti-CGRP...
Observational Study
European journal of neurology. 2026 Jul;33(7):e70714. DOI:10.1111/ene.70714 2026
Corticospinal Subfiber Neurite Density Index Detects Upper Motor Neuron Degeneration in Prediagnostic Patients With Sporadic Amyotrophic Lateral Sclerosis [0.03%]
皮质脊髓亚纤维轴突密度指数可检测散发性肌萎缩侧索硬化症前诊断患者的上运动神经元变性
Ninglu Gao,Bo Cui,Yan Yun et al.
Ninglu Gao et al.
Background: Using multi-shell diffusion MRI, we aimed to identify whether corticospinal tract (CST) subfiber damage can be detected in prediagnostic amyotrophic lateral sclerosis (ALS) patients. We also explored whether t...
Real-Life Effectiveness After Switching to Avalglucosidase Alfa in Late-Onset Pompe Disease Patients Worsening on Alglucosidase Alfa Therapy: A French Cohort Study [0.03%]
阿维鲁 glut2抑制剂 alfa治疗庞贝病晚期患者的有效性：一项法国队列研究
Céline Tard,Sabrina Sacconi,Nadjib Taouagh et al.
Céline Tard et al.
Late-onset Pompe disease (LOPD) is a progressive myopathy. Enzyme replacement therapy is effective, but long-term outcomes vary. Avalglucosidase alfa, shown to be non-inferior to alglucosidase alfa in a phase 3 trial, became available in Fr...
Sleep Disorders in Medication-Overuse Headache: Prevalence and Associated Factors [0.03%]
药物过度使用性头痛的睡眠障碍及其相关因素流行病学研究
Elena R Lebedeva,Iana A Kniazeva,Denis V Gilev et al.
Elena R Lebedeva et al.
Background: Sleep disorders can exacerbate headache burden, yet their prevalence and reversibility in medication-overuse headache (MOH) remain unexplored. We aimed to evaluate sleep disorders and associated factors in MOH...
Diagnostic Value of Spinal Cord Lesion Metabolism on [18F]FDG PET/CT for the Classification of Myelopathy [0.03%]
[18F]FDG正电子发射断层显像/计算机体层成像脊髓病灶代谢诊断脊髓病变价值研究
Antoine Gavoille,Anthime Flaus,Matthieu Dietz et al.
Antoine Gavoille et al.
Introduction: [18F]FDG PET/CT scan is sometimes performed as part of the diagnostic evaluation of non-compressive myelopathies, but the spinal cord lesion metabolism is not systematically evaluated. We aimed to investigat...
Speech-In-Noise Perception in Alzheimer's Disease and Primary Progressive Aphasia [0.03%]
阿尔茨海默病和原发性进行性失语患者的噪声环境言语理解能力下降
Sophie A Froud,Benjamin A Levett,Jessica Jiang et al.
Sophie A Froud et al.
Background: Understanding speech despite background noise is essential for everyday communication, but makes heavy neural processing demands. It is therefore potentially vulnerable to neurodegenerative diseases, particula...
Vascular-Apoptotic Crosstalk in Alzheimer's Disease: The Possible Role of Vascular Senescence in Blood-Brain Barrier Dysfunction [0.03%]
血管凋亡在阿尔茨海默病中的相互作用：血管衰老在血脑屏障功能障碍中可能扮演的角色
Carlangelo Carrese,Chiara Giuseppina Bonomi,Francesca Bernocchi et al.
Carlangelo Carrese et al.
Background: Blood-brain barrier (BBB) dysfunction is an early feature of Alzheimer's disease (AD), influenced by amyloid pathology, astrocyte activation, and vasoactive mediators such as endothelin-1 (ET-1). ET-1 has been...