Subcutaneous Levodopa in Parkinson's Disease: A Systematic Review and Meta-Analysis [0.03%]
帕金森病下丘脑左旋多巴：系统性评审和元分析
Matthew Burton,Duncan Marsden,Dhruv Harish et al.
Matthew Burton et al.
Background: Many Parkinson's disease patients receiving oral levodopa/carbidopa experience a troublesome wearing off effect. Higher doses to mitigate OFF-time are limited by adverse effects occurring at peak dopamine leve...
Victor Alm,Linda Säll,Kristin Samuelsson et al.
Victor Alm et al.
Background: Biallelic pentanucleotide expansions in RFC1 cause cerebellar ataxia, neuropathy, vestibular areflexia syndrome (CANVAS), and a growing spectrum of presentations. We aimed to clinically characterize a cohort o...
A National Danish Effectiveness Study of Ocrelizumab Versus Natalizumab in Multiple Sclerosis [0.03%]
丹麦奥瑞珠单抗与那他珠单抗治疗多发性硬化的全国疗效研究
Camilla Maersk-Moller,Luigi Pontieri,Morten Leif Munding Stilund et al.
Camilla Maersk-Moller et al.
Background: Ocrelizumab and natalizumab are highly effective disease-modifying treatments for relapsing-remitting multiple sclerosis (RRMS). Direct comparison of effectiveness is crucial for optimizing treatment decisions...
Comparative Study
European journal of neurology. 2026 Feb;33(2):e70507. DOI:10.1111/ene.70507 2026
Clinical Validation of α-Synuclein in Salivary Extracellular Vesicles as a Biomarker for Parkinson's Disease: A Longitudinal Study [0.03%]
唾液外泌体α-突触核蛋白作为帕金森病生物标志物的临床验证：一项纵向研究
Antonia Gurgone,Vita Cardinale,Marta M Tangari et al.
Antonia Gurgone et al.
Background: Parkinson's disease (PD) is a progressive neurodegenerative disorder characterized by the accumulation of misfolded alpha-synuclein (α-Syn) and the subsequent loss of dopaminergic neurons. Identifying reliabl...
Reduced Frequency of Prolonged Sporadic Hemiplegic Migraine Attacks Following Fremanezumab Treatment-A Case Report [0.03%]
关于费米扎单抗治疗后散发性半侧瘫痪型偏头痛发作频率降低的病例报告
Julian Frederic Hotz,Lisa Kaindl,Stefan Krebs et al.
Julian Frederic Hotz et al.
Introduction: Hemiplegic migraine (HM) is a rare subtype of migraine with aura, characterized by transient, unilateral motor weakness. Due to its rarity, treatment strategies are lacking. Monoclonal antibodies targeting t...
1-Year Clinical Outcome Post-Myasthenic Crisis: A Multicenter Prospective Study in China [0.03%]
中国多中心重症肌无力危象后一年临床转归的前瞻性研究
Xiao Huan,Ran Chen,Lei Jin et al.
Xiao Huan et al.
Background: Myasthenic crisis (MC) affects 10%-20% of myasthenia gravis patients and is life-threatening with significant economic burden, yet its long-term outcomes remain poorly understood. This prospective multicentre ...
Multicenter Study
European journal of neurology. 2026 Feb;33(2):e70513. DOI:10.1111/ene.70513 2026
Systemic Arterial Stiffness in Reversible Cerebral Vasoconstriction Syndrome: A Prospective Case-Control Study [0.03%]
可逆性脑血管收缩综合征的全身动脉僵硬度：一项前瞻性病例对照研究
Pacôme Constant Dit Beaufils,Laëtitia Barbin,Morgane Pere et al.
Pacôme Constant Dit Beaufils et al.
Background: Reversible cerebral vasoconstriction syndrome (RCVS) is a neurovascular disorder with unclear pathophysiology, particularly concerning systemic endothelial function. Understanding arterial stiffness could shed...
Interpreting the Mediating Variable of PPP Through Appropriate Design and Rigorous Measurement Methods [0.03%]
通过合理的设计和严格的测量方法诠释PPP的中介变量
Leqi Gao,Jiazhao Song,Hongwei An
Leqi Gao
Conduction Block Detection in Dysimmune Neuropathy: Hypothetical Pathophysiological 'Truth' Versus Clinical Pragmatism [0.03%]
自身免疫性神经病传导阻滞的检测：假设的病理生理“真理”与临床实用主义之间的差异
Yusuf A Rajabally,Ahmad Al-Areed
Yusuf A Rajabally
Response to the Comment by Steinkirchner et al. On the Article "Variation in Repeated Handgrip Strength Testing Indicates Submaximal Force Production in Patients With Myalgic Encephalomyelitis/Chronic Fatigue Syndrome" [0.03%]
对Steinkirchner等人关于论文“肌阵挛性脑脊髓炎/慢性疲劳综合症患者反复握力测试的变化表明亚最大力量产生”的评论的回复
Stoyan Popkirov
Stoyan Popkirov