Risdiplam Impact in Treatment Naïve and Non-Naïve Pediatric and Adult Patients With Spinal Muscular Atrophy [0.03%]
risdiplam在脊髓性肌萎缩症初治和非初治儿科及成人患者中的影响
Pak On Patrick Yee,Hayley Hoi Ning Ip,Michael Kwan Leung Yu et al.
Pak On Patrick Yee et al.
Background: Risdiplam, an oral disease-modifying therapy, has demonstrated safety and efficacy in clinical trials, but real-world data from Asia are limited. ...
Interventions for Migraine and Sleep: A Systematic Review Exploring Their Bidirectional Association [0.03%]
头痛和睡眠干预的系统评价：探索它们之间的双向联系
Marco Sforza,Ilaria Mariani,Federica Fazzini et al.
Marco Sforza et al.
Background: Migraine and sleep disturbances share a bidirectional relationship, influencing each other's frequency and severity. The aim of this systematic review is to examine the effects of migraine-targeted interventio...
Gait Parameters Alterations Under Dual-Task Conditions in Patients With Acquired and Hereditary Peripheral Neuropathies [0.03%]
双任务条件下获得性和遗传性外周神经病患者的步态参数改变
Loïc Dupont,Romain Thomas,Loïc Danjoux et al.
Loïc Dupont et al.
Introduction: Peripheral demyelinating neuropathies impair gait and increase fall risk, particularly under cognitively demanding conditions. While gait disturbances in chronic inflammatory demyelinating polyradiculoneurop...
Quantitative Whole-Body Muscle MRI in Adults With Spinal Muscular Atrophy-A Sensitive Tool for Long-Time Evaluation of Disease Progression [0.03%]
脊髓性肌萎缩成人患者全身肌肉定量磁共振成像研究——评估疾病进展的敏感工具
Alexander Mensch,Benjamin Troppa,Ilka Schneider et al.
Alexander Mensch et al.
Background: Spinal muscular atrophy (SMA) is a neuromuscular disorder characterized by progressive muscle weakness due to SMN protein deficiency. While effective therapies exist, their impact on slowly progressive adult S...
Muscle MRI and Muscle Ultrasound Applications in MND/ALS: Academic Insights and Clinical Opportunities [0.03%]
肌营养不良症/渐冻症(MND/ALS)中的肌肉MRI和肌肉超声应用：学术见解与临床机遇
Alison Toomey,Jana Kleinerova,Ee Ling Tan et al.
Alison Toomey et al.
Background: There is an unmet need for the clinically relevant ALS biomarkers to facilitate an accurate diagnosis in suspected cases, monitor disease progression and evaluate response to therapy in clinical trials. While ...
Marina Romozzi,Federico Tosto,Annalisa Gentile et al.
Marina Romozzi et al.
Background: Neuroinflammatory and systemic immune mechanisms are increasingly recognized as contributors to migraine pathophysiology. However, peripheral markers of inflammation remain underexplored. This study aimed to e...
Paramagnetic Rim Lesions in Highly Active Multiple Sclerosis at the Time of Disease Diagnosis: Prevalence Data and Clinical Implications [0.03%]
高度活跃的多发性硬化症患者在发病时磁共振中边缘区域出现顺磁性病变的流行率及临床意义
Alessandra Cicia,Matteo Lucchini,Gianluca Di Fiore et al.
Alessandra Cicia et al.
Background: Paramagnetic rim lesions (PRLs) are emerging MRI biomarkers of smoldering inflammation in multiple sclerosis with prognostic relevance1. However, their prevalence in the early stages of the disease remains und...
Development and Validation of a Visual Grading Score of Disease Severity From Gait Videos in Genetic Peripheral Neuropathy [0.03%]
遗传性外周神经病步态视频疾病严重程度视觉评分的开发和验证
Helena F Pernice,Emanuele Piazza,Eleonora Asaad et al.
Helena F Pernice et al.
The Clinical Eye Score (CES) is a score to grade disease severity in peripheral neuropathy visually from videos of patients walking. It correlates strongly with state-of-the-art outcome measures for peripheral neuropathy in patients with CM...
Multiple Mononeuropathy Secondary to Parvovirus B19 Infection: A Case Series [0.03%]
由B19型细小病毒感染引起的多发单神经病：一系列病例报告
Julian Theuriet,Maud Michaud,Guillaume Fargeot et al.
Julian Theuriet et al.
Background: Parvovirus B19 (B19V) infection has been associated with neurological complications. Rarely, patients present with multiple mononeuropathy (MM). The present study aimed to better characterize the clinical, ele...
Observational Study
European journal of neurology. 2026 Mar;33(3):e70565. DOI:10.1111/ene.70565 2026
AI-Based Methods in Neuropathology for Diagnosis and Treatment of Brain Tumors [0.03%]
基于人工智能的神经病理学在脑肿瘤诊断和治疗中的应用方法
Thomas Roetzer-Pejrimovsky,Nicole Amberg,Georg Widhalm et al.
Thomas Roetzer-Pejrimovsky et al.
Background: Artificial Intelligence (AI) is rapidly emerging as a transformative tool in medical research and practice. In neuro-oncology, AI may help to enhance diagnostic accuracy and reproducibility, manage complex mul...