Comparative Effectiveness and Safety of Rituximab Versus Ocrelizumab in Relapsing-Remitting Multiple Sclerosis: A Finnish Population-Based Matched Cohort Study [0.03%]
利妥昔单抗与奥瑞珠单抗治疗复发型多发性硬化症的疗效和安全性比较:一项基于芬兰人口的队列研究
Maiju Savolainen,Merja Soilu-Hänninen,Henriikka Nurmi et al.
Maiju Savolainen et al.
Background: B-cell-depleting anti-CD20 therapies are among the most effective disease-modifying treatments for relapsing-remitting multiple sclerosis (RRMS). Rituximab (RTX) is widely used off-label, while ocrelizumab (OC...
Comparative Study
European journal of neurology. 2026 May;33(5):e70625. DOI:10.1111/ene.70625 2026
HLA Class I Haplotype in Glutamic Acid Decarboxylase Antibody-Associated Neurological Disease [0.03%]
与谷氨酸脱羧酶抗体相关的神经病的HLAⅠ类等位基因及单倍型分析
Lin Bai,Haitao Ren,Qiang Lu et al.
Lin Bai et al.
Object: Glutamic acid decarboxylase antibody-associated neurological disease (GADAND) is a rare autoimmune disorder with elusive immunogenetic underpinnings. We aimed to investigate HLA associations with GADAND susceptibi...
Functional Stroke Mimics: Patient Characteristics, CT-Based Multimodal Imaging and Long-Term Outcome in a Comparative Cohort Study [0.03%]
功能性卒中模仿症:基于患者的特征、CT多模式影像和长期结果的比较队列研究
Filipa Bastos,Davide Strambo,Alexander Salerno et al.
Filipa Bastos et al.
Background and purpose: Functional stroke-like episodes (FSMs) are an increasingly recognised stroke mimic with demographic and clinical characteristics that differ from acute ischaemic strokes (AISs) but have unclear lon...
Comparative Study
European journal of neurology. 2026 May;33(5):e70617. DOI:10.1111/ene.70617 2026
A Population-Based Study of Posterior Reversible Encephalopathy Syndrome and Reversible Cerebral Vasoconstriction Syndrome During Pregnancy and Puerperium [0.03%]
一项关于妊娠期和产褥期后可逆性脑病综合征与可逆性脑血管收缩综合征的流行病学研究
Vest Teresa,Verho Liisa,Rantanen Kirsi et al.
Vest Teresa et al.
Background: Posterior reversible encephalopathy syndrome (PRES) and reversible cerebral vasoconstriction syndrome (RCVS) are related neurovascular conditions, with pregnancy as a shared risk factor. In this study, we aime...
Cognitive Impairment Beyond Neurodegenerative Dementias: New Frontiers for Cognition in Neurological Disease [0.03%]
超越神经退行性痴呆的认知障碍:神经系统疾病认知研究的新前沿
Paulo Caramelli,Isabel Pavão Martins
Paulo Caramelli
Explainable Artificial Intelligence to Predict Neurocognitive Disorder Progression in Multiple Sclerosis Using MRI and Clinical Data [0.03%]
基于MRI和临床数据预测多发性硬化认知障碍进展的可解释人工智能方法
Loredana Storelli,Damiano Mistri,Alice Mastropasqua et al.
Loredana Storelli et al.
Background: Cognitive impairment is common in multiple sclerosis (MS), yet the application of diagnostic frameworks of Neurocognitive Disorders (NCDs) is limited. Additionally, the integration of multimodal data for predi...
Identification and Functional Characterization of Novel and Recurrent NTRK1 Variants in Chinese Families With Congenital Insensitivity to Pain With Anhidrosis: A Combined Clinical, Genetic, and Functional Study [0.03%]
中国人Congenital Insensitivity to Pain With Anhidrosis家系中NTRK1新发及复发变异的识别与功能表征:一项临床、遗传和功能研究联合分析
Yaqiong Ren,Yue Cao,Fangfang Cheng et al.
Yaqiong Ren et al.
Background: Congenital insensitivity to pain with anhidrosis (CIPA) is an autosomal recessive disorder caused by variants in the NTRK1 gene (encoding TrkA). The identification and functional analysis of these variants are...
The Relevance of Crystal Clear and Unclear Days to Evaluate Residual Interictal Burden in Patients With Migraine Treated With CGRP Monoclonal Antibodies [0.03%]
结晶清晰和不清晰的日子与评估CGRP单克隆抗体治疗偏头痛患者的残留间歇期负担的相关性
Marcello Silvestro,Ilaria Orologio,Raffaele Ornello et al.
Marcello Silvestro et al.
Background: Although treatment goals in migraine prevention have moved beyond the benchmark of a 50% reduction in monthly attacks, residual disease burden is still evaluated based on residual headache frequency. However, ...
Paul Philipp Kastner,Pia Lena Niederau,Georgios Pantazis et al.
Paul Philipp Kastner et al.
Background: Subacute oculomotor dysfunction encompasses a broad differential diagnosis, including autoimmune, infectious, vascular, and neoplastic etiologies. Primary skull base diffuse large B-cell lymphoma (DLBCL) is a ...
Characteristics of Patients with Myasthenia Gravis in the French Rare Disease Registry [0.03%]
法国罕见病注册中心重症肌无力患者的特点
Jean-Philippe Camdessanche,Andoni Echaniz-Laguna,Guilhem Solé et al.
Jean-Philippe Camdessanche et al.
Background: The French National Rare Diseases Registry (BNDMR) was established in 2007 to ensure access to optimal care standards for all patients with rare diseases in dedicated reference centres. The objective of this r...