Eating behaviour in contrasting adiposity phenotypes: Monogenic obesity and congenital generalized lipodystrophy [0.03%]
不同肥胖表型的饮食行为：单基因肥胖和先天性广义脂质营养不良
José L Santos,Víctor A Cortés
José L Santos
Most known types of nonsyndromic monogenic obesity are caused by rare mutations in genes of the leptin-melanocortin pathway controlling appetite and adiposity. In contrast, congenital generalized lipodystrophy represents the most extreme fo...
What is the impact of food reformulation on individuals' behaviour, nutrient intakes and health status? A systematic review of empirical evidence [0.03%]
食品改革对个人行为、营养摄入和健康状况的影响是什么？一项经验证据的系统回顾
Mathilde Gressier,Boyd Swinburn,Gary Frost et al.
Mathilde Gressier et al.
Food reformulation aimed at improving the nutritional properties of food products has long been viewed as a promising public health strategy to tackle poor nutrition and obesity. This paper presents a review of the empirical evidence (i.e.,...
Nutritional intervention strategies for the management of overweight and obesity in primary health care: A systematic review with meta-analysis [0.03%]
初级保健中超重和肥胖的营养干预策略：一项带有元分析的系统性综述
Raquel Canuto,Anderson Garcez,Renata Vieira de Souza et al.
Raquel Canuto et al.
A systematic review with meta-analysis (MA) was conducted to synthesize the effectiveness of nutrition intervention strategies for managing overweight and obesity in the adult population attending primary health care. Relevant articles were...
Expanding our understanding and use of the ecological systems theory model for the prevention of maternal obesity: A new socioecological framework [0.03%]
扩大我们对生态体系理论模型的理解和使用以预防母体肥胖：一个新的社会生态系统框架
Briony Hill
Briony Hill
The reproductive life phase, most notably the preconception, pregnancy and postpartum periods, is a key driver of weight gain in women and therefore substantially increases the risk of noncommunicable diseases for mothers and their offsprin...
Is there an exposure-effect relationship between body mass index and invasive mechanical ventilation, severity, and death in patients with COVID-19? Evidence from an updated meta-analysis [0.03%]
身体指数与COVID-19患者有创机械通气、疾病严重程度和死亡率之间的关系？来自最新荟萃分析的证据
Menglu Liu,Chao Deng,Ping Yuan et al.
Menglu Liu et al.
Epigenetic regulation of adipose tissue expansion and adipogenesis by N6 -methyladenosine [0.03%]
N6-甲基腺苷对脂肪组织扩展和脂肪生成的表观遗传调控
Ruifan Wu,Xinxia Wang
Ruifan Wu
Obesity, defined as excessive fat accumulation, is strongly associated with metabolic diseases and cancer, and its prevalence is rising worldwide. Thus, understanding the molecular mechanism of adipogenesis is of fundamental significance. E...
Metabolic tissue-resident CD8+ T cells: A key player in obesity-related diseases [0.03%]
代谢组织驻留的CD8+ T细胞：肥胖相关疾病的关键参与者
Lina Wang,Ping Sun,Yuzhang Wu et al.
Lina Wang et al.
Obesity-induced low-grade chronic inflammation in the metabolic tissues, such as adipose tissue (AT) and liver tissue, in individuals with obesity is a major etiological factor for several diseases, such as insulin resistance, type 2 diabet...
The role of protein kinase D (PKD) in intracellular nutrient sensing and regulation of adaptive responses to the obese environment [0.03%]
蛋白激酶D(PKD)在细胞内营养物质感应中的作用及其对肥胖环境适应性反应的调控作用
Mark C Renton,Sean L McGee,Kirsten F Howlett
Mark C Renton
Obesity is associated with ectopic accumulation of lipids, which is implicated in the development of insulin resistance, type 2 diabetes mellitus and cardiovascular disease. As the global prevalence of obesity continues to rise, it is becom...
Effect of obesity and body mass index on coronavirus disease 2019 severity: A systematic review and meta-analysis [0.03%]
肥胖和体质指数对2019冠状病毒疾病严重程度的影响：系统回顾和荟萃分析
Tu-Hsuan Chang,Chia-Ching Chou,Luan-Yin Chang
Tu-Hsuan Chang
We conducted a systematic review of observational studies to examine the effects of body mass index (BMI) and obesity (BMI ≥ 30 kg/m2 ) on coronavirus disease 2019 (COVID-19). Medline, Embase, and the Cochrane Library were searched. Sixtee...