Identification of Common Molecular Signatures in Chronic Obstructive Pulmonary Disease and Pulmonary Tuberculosis [0.03%]
慢性阻塞性肺疾病与肺结核共性分子标志物的识别
Stanislav Kotlyarov,Dmitry Oskin
Stanislav Kotlyarov
Chronic obstructive pulmonary disease (COPD) and pulmonary tuberculosis (TB) are major causes of morbidity and mortality worldwide. Epidemiologic studies indicate an increased risk of tuberculosis in patients with COPD; however, the shared ...
Characterization of Arthrospira platensis NH Draft Genome [0.03%]
变异体Arthrospira platensis NH染色体的基因组草图及其生物学特性的研究
Trang Thi Huyen Nguyen,Anh Minh Pham,Linh Khanh Chu et al.
Trang Thi Huyen Nguyen et al.
This study aimed to characterize the draft genome of Arthrospira platensis NH isolated in Vietnam and evaluate its phylogenetic position within cyanobacteria. Phylogenetic analysis based on 16S rRNA gene sequences confirmed that A. platensi...
Agro-Industrial Plant Biomass as a Sustainable Source of Anticancer Polyphenols: Molecular Mechanisms and Future Perspectives [0.03%]
农业工业植物生物质作为抗癌多酚的可持续来源：分子机制和未来前景
Sorur Yazdanpanah,Fabrizia Sepe,Silvia Romano et al.
Sorur Yazdanpanah et al.
The increasing global burden of cancer, together with the need for more sustainable resource management, has stimulated growing interest in the valorization of agro-industrial plant residues as sources of bioactive compounds with therapeuti...
Gla-Rich Protein (GRP): A Vitamin K-Dependent Regulator of Vascular Calcification, Inflammation, and Mineral Homeostasis [0.03%]
富含GLA的蛋白质（GRP）：一种维生素K依赖性血管钙化、炎症和矿物质稳态调节因子
Antun Loncaric,Lara Baticic
Antun Loncaric
Gla-rich protein (GRP), also known as UCMA, is a vitamin K-dependent protein that has emerged as an important regulator of pathological calcification and inflammation. Vascular calcification is a major complication of chronic kidney disease...
Advances in the Association Between the ADRB2 Gene and Bronchial Asthma: Genetic Polymorphisms, Epigenetic Regulation, and Clinical Applications [0.03%]
ADRB2基因与支气管哮喘关联研究进展：遗传多态性、表观调控及临床应用
Xiaolong Sun,Yang Li,Yiyao Bao
Xiaolong Sun
Bronchial asthma is a common chronic respiratory disease with a complex etiology, wherein the interaction between genetic and environmental factors plays a critical role in its pathogenesis. The β-2 adrenergic receptor gene (ADRB2) is pivo...
POU6F1 Expression Predicts Favorable Prognosis in Lung Adenocarcinoma: Validation Using Patient Cohort and TCGA Data [0.03%]
POU6F1表达可预测肺癌腺癌预后佳：采用患者队列和TCGA数据验证
Mincheol Chae,Jae-Ho Lee,Hyowon Hong et al.
Mincheol Chae et al.
Non-small cell lung cancer (NSCLC) is the most common type of lung cancer and remains a leading cause of cancer-related mortality worldwide. Lung adenocarcinoma (AD) and lung squamous cell carcinoma (SCC) represent the two major histologica...
Clinical Course of Severe Perineal Hypospadias with Cryptorchid Testicular Tumors in a Dog: Contextual Reference to Developmental and Endocrine Transcriptomic Pathways [0.03%]
一只犬严重阴茎阴囊位置异常合并隐睾肿瘤的临床过程：与发育和内分泌转录组途径的相关性参考
Nuri Lee,Kibum Kwon,Ahsa Oh et al.
Nuri Lee et al.
Hypospadias is a congenital malformation of the male external genitalia resulting from incomplete fusion of the urethral folds during embryonic development. The perineal form represents the most severe phenotype and is frequently associated...
Serglycin Across the Disease Spectrum: A Multifunctional Proteoglycan in Inflammation and Cancer [0.03%]
Serglycin在疾病谱系中的作用：炎症和癌症中的一种多功能蛋白聚糖
Eleftherios N Athanasopoulos,Vassiliki T Labropoulou,Achilleas D Theocharis
Eleftherios N Athanasopoulos
The inflammatory response possesses a central role in human pathophysiology, regulating the tissue microenvironment and cell signaling. Inflammation occurs either as a symptom of homeostasis disturbance or as a driver for determining cell f...
Mechanistic Insights into Glycine's Regulation of Milk Protein Synthesis via PI3K-AKT-mTOR Signaling [0.03%]
甘氨酸通过PI3K-AKT-mTOR信号途径调控乳蛋白合成的机制研究
Xinyu Zhang,Yu Ding,Min Yang et al.
Xinyu Zhang et al.
Amino acids play a dual role in milk protein synthesis, functioning as both metabolic precursors and signaling molecules. This study aimed to elucidate the molecular mechanism by which glycine regulates α-casein production in bovine mammar...
OATP1B3 c.699G>A Predicts a 6.3-Fold Increased Risk of Hyperbilirubinemia During OPrD Therapy for HCV [0.03%]
OATP1B3 c.699G>A预测在治疗HCV期间OPrD疗法发生高胆红素血症的风险增加6.3倍
Zuhal Altintas,Engin Altintas
Zuhal Altintas
Although ombitasvir/paritaprevir/ritonavir plus dasabuvir (OPrD) therapy is highly effective for chronic hepatitis C (CHC), clinicians frequently encounter transient hyperbilirubinemia, which can be misidentified as hepatotoxicity. This stu...