Proteomic Studies in Absence Epilepsy: A Systematic Review of Methodological Diversity and Implications for Data Interpretation [0.03%]
无缺体癫痫的蛋白质组学研究：方法多样性和数据解释的影响的系统性综述
Aslihan Gunel
Aslihan Gunel
Absence epilepsy (AE) is a common pediatric epilepsy syndrome marked by brief lapses in consciousness and characteristic 2.5-4 Hz spike-and-wave discharges on EEG. Although its clinical and electrophysiological features are well established...
Therapeutic Insights and Immune Pathway Connections Revealed by Core Symptom Gene Network Analysis in Ankylosing Spondylitis [0.03%]
基于核心症状基因网络分析揭示强直性脊柱炎治疗靶点及免疫通路联系
La Yoon Choi,Mi Hye Kim,Dae Yong Kim
La Yoon Choi
Ankylosing spondylitis (AS) exhibits marked clinical heterogeneity that is poorly captured by conventional disease-centric analyses, hindering the development of personalized therapies. We propose a symptom-centered network pharmacology fra...
Pollution-Induced Allergy Skews Metabolism Toward Obesity-A Conceptual Review [0.03%]
环境污染引起的过敏向肥胖代谢转变的概念性回顾文章摘要
Kaustubh Jumle,Fehmi Boufahja,Anis Ahmad Chaudhary et al.
Kaustubh Jumle et al.
Rapid urbanization and significant lifestyle changes have become the risk drivers for the epidemiology of diseases. With urban transitions, substantial persistence of pollutants in the environment has been observed. Epidemiological studies ...
γ-Amino Carboxylic Acid Modification Enhances the Efficacy of Peptide Nucleic Acids Targeting miR-221-3p in Lung Cancer Cell Lines [0.03%]
γ-氨基羧酸修饰增强肽核酸在肺癌细胞系中靶向miR-221-3p的疗效
Youngsim Yoon,Na-Rae Joo,Taewoo Kim et al.
Youngsim Yoon et al.
Peptide nucleic acids (PNAs) are versatile molecules with promising diagnostic and therapeutic applications, including gene expression regulation and miRNA targeting. However, their moderate biological efficacy limits their therapeutic appl...
A Review of Ionizing Radiation-Induced Senescence of Bone Marrow Mesenchymal Stem/Stromal Cells: Mechanisms and Therapeutic Strategies [0.03%]
骨髓间充质干细胞/基质细胞衰老的电离辐射诱导机制及治疗策略综述
Xiaoliang Li,Maoshan Chen,Yangyang Zhang et al.
Xiaoliang Li et al.
Bone marrow mesenchymal stem/stromal cells (BM-MSCs) are important components of bone marrow, possessing multipotent differentiation potential and the ability to support hematopoiesis. Exposure to ionizing radiation (IR) induces cellular da...
Walnut Green Husk Polysaccharide Improve Gut Microbiota and Alleviate Intestinal Inflammation Caused by Immune Checkpoint Inhibitors [0.03%]
核桃青皮多糖可改善免疫检查点抑制剂引起的肠道菌群失调及肠炎症状
Yunting Deng,Yannan Zhang,Bowen Yan et al.
Yunting Deng et al.
In this study, the structure of Walnut green husk polysaccharides (WGHP) and their effects on immune checkpoint inhibitor induced colitis (ICIIC) and intestinal microbiota in mice were studied. The results showed that WGHP was composed of m...
Reply to Lago, T.R.; Bolognani, F. Comment on "Nazarloo et al. Oxytocin, Vasopressin and Stress: A Hormetic Perspective. Curr. Issues Mol. Biol. 2025, 47, 632" [0.03%]
对Lago和Bolognani关于“Nazarloo等人. 催产素、血管加压素与压力：激素视角”的评论的回复
Hans P Nazarloo,Marcy A Kingsbury,Hannah Lamont et al.
Hans P Nazarloo et al.
We thank Lago and Bolognani [...].
Multifunctional Bioactivity of Bacillus amyloliquefaciens SH-53: Analysis of Multiple Antagonistic and Synergistic Growth Promotion Mechanisms Based on Whole Genome [0.03%]
枯草芽孢杆菌SH-53多功能生物活性及其多抗性和促生长协同机制的全基因组分析
Jianpeng Jia,Yu Wang,Xin Liu et al.
Jianpeng Jia et al.
Bacillus amyloliquefaciens is an important agricultural microbial resource. This study focuses on the whole genome analysis and functional characterization of B. amyloliquefaciens SH-53, isolated from the Wuliang Mountain National Nature Re...
Generation of an Insecticidal Human Domain Antibody from a Phage Library Targeting Plutella xylostella Brush-Border Membrane Vesicles [0.03%]
一种针对甘蓝夜蛾肠上皮刷状缘膜囊泡的噬菌体抗体文库中筛选获得杀虫单域抗体
Xiaodan Hu,Xiao Zhang,Junmin Fan et al.
Xiaodan Hu et al.
The importance of protein-based materials in agricultural pest control has received increasing attention in recent years. Herein, Plutella xylostella brush-border membrane vesicles (BBMVs) were used as a target to screen for human domain an...
Diverse Bacterial Anti-Phage Strategies: From the Laboratory to the Clinic [0.03%]
多样化的细菌抗噬菌体策略：从实验室到临床
Yong Shao,Zhu Gao,Ying Zhang et al.
Yong Shao et al.
Refractory infections caused by multidrug-resistant bacteria have emerged as a substantial threat to public health, prompting renewed interest in phage therapy. Bacteria and phages are ubiquitous in diverse environments, engaging in continu...