Jakub Wnuk,Wiktoria Skowron,Anna Długaszek et al.
Jakub Wnuk et al.
Pancreatic cancer (PC) is considered one of the deadliest cancers worldwide, and the number of PC-related deaths is expected to increase. Early diagnosis of PC is crucial for improving treatment outcomes. Despite improvements in overall sur...
DNA Barcoding and Comparative Chloroplast Marker Performance in Endemic Plants of Crete (Greece) [0.03%]
基于DNA条形码的植物分子鉴定及其在克里特岛（希腊）植物中的应用研究
Dimitra Ioannidou,Ioulietta Samartza,Georgios Tsoktouridis et al.
Dimitra Ioannidou et al.
Crete, a major Mediterranean biodiversity hotspot, hosts many local endemic, threatened and/or protected plant taxa (species and subspecies). Besides their ecological and conservation significance, these unique phytogenetic resources hold s...
Oncolytic Herpes Simplex Virus for Glioblastoma: Molecular Engineering, Tumor Microenvironment Barriers, and Clinical Translation [0.03%]
溶瘤单纯疱疹病毒治疗胶质母细胞瘤：分子工程、肿瘤微环境障碍及临床转化
Jiayu Liu,Yuxin Wang,Zhao Gao et al.
Jiayu Liu et al.
Glioblastoma (GBM) remains the most aggressive primary malignant brain tumor in adults, with limited survival benefit from the current standard of care consisting of maximal safe resection, radiotherapy, and temozolomide-based chemotherapy....
Revision of Energy Metabolism Adaptations in High-Level Athletes: From Physical Performance Enhancement to Potential Therapeutic Targets in Mental Disorders [0.03%]
高水平运动员能量代谢适应的修订：从运动表现提升到精神疾病潜在治疗靶点
Ane Larrea,Mariyem Naji,Marina Gulak et al.
Ane Larrea et al.
High-level athletic performance requires the implementation of personalized strategies based on the analysis of metabolic pathways involved in energy production: phosphagen, glycolytic, and oxidative pathways. In this context, mitochondria ...
Application of Raman Spectroscopy to Rapid Discrimination of Autochthonous Lactic Acid Bacteria Isolated from Goat Cheese [0.03%]
拉曼光谱技术快速鉴别山羊奶酪中乳酸菌种系的新方法研究
Ana Yanina Bustos,Juan José Carol Paz,Jorge Nicolás Gómez et al.
Ana Yanina Bustos et al.
The rapid characterization of lactic acid bacteria (LAB) with probiotic and technological properties is crucial for functional food design. In this study, fourteen LAB strains belonging to the species Lactiplantibacillus (L.) plantarum, Len...
Potential Prognostic and Metastatic Implications of MACC1 and MMP8 in Colorectal Cancer [0.03%]
MACC1和MMP8在结直肠癌预后及转移中的潜在作用
Hilal Oğuz Soydinç,Sena Şen,Murat Serilmez et al.
Hilal Oğuz Soydinç et al.
Colorectal cancer (CRC) remains a major cause of cancer-related morbidity and mortality worldwide. Metastasis regulators and matrix metalloproteinases have been implicated in tumor progression; however, their clinical significance in CRC re...
In Vitro Anti-Inflammatory Activity and Molecular Docking Analysis of Compounds Isolated from Beyeria viscosa [0.03%]
拜尔利亚粘胶化合物的体外抗炎活性及分子对接分析
Hamza Shahid,James P Flood,Feng Li et al.
Hamza Shahid et al.
Inflammation contributes to the progression of numerous chronic diseases, and plants are a rich source of bioactive secondary metabolites. In this study, bioassay-guided isolation of the previously unexplored Australian native plant Beyeria...
Immune-Enhancing Effects of Polygonatum cyrtonema Polysaccharides in Immunodeficient Zebrafish [0.03%]
Polygonatum cyrtonema多糖通过补益脾肾提高免疫缺陷斑马鱼免疫力的研究
Daoyuan Li,Jie Wang,Naifu Chen et al.
Daoyuan Li et al.
To evaluate the immune-enhancing effects of Polygonatum cyrtonema polysaccharides in vivo, an immunodeficiency zebrafish model was established by microinjecting vinorelbine tartrate into the caudal vein. Effects of the polysaccharides (500,...
Microbial Dysbiosis in Photodermatoses: Formation, Pathogenesis and Intervention Strategies [0.03%]
光感性皮肤病相关微生物菌群失调的研究：形成、致病及干预策略
Lanhai Zhong,Tian Wang,Lu Tang et al.
Lanhai Zhong et al.
Recent studies have reported skin microbiome dysbiosis in patients with photodermatoses, featuring enriched Staphylococcus aureus colonization and decreased microbiome diversity. We propose that ultraviolet radiation (UVR), along with atypi...
Molecular Target Discovery and Systemic Mechanism Analysis of Teriflunomide for Dry Eye Disease [0.03%]
特立氟胺治疗干眼病的分子靶点发现及系统药理机制分析
Yang Chen,Weiran Lin,Wei Feng et al.
Yang Chen et al.
Background: Dry eye disease (DED) is a multifactorial ocular surface disorder characterized by tear film instability, inflammation, and neurosensory abnormalities. Current therapies remain limited by slow onset and subopt...