Genome-Wide Analysis of bZIP Transcription Factors and Expression Patterns in Response to Shading Treatment in Taxus yunnanensis [0.03%]
云南红豆杉bZIP家族基因的鉴定及遮阴处理对其表达模式的影响分析
Jiangtao Fan,Pengpeng Gong,Yujia Liu et al.
Jiangtao Fan et al.
Basic leucine zipper (bZIP) transcription factors are widely involved in plant growth, development, environmental adaptation, and secondary metabolism. However, the bZIP gene family in Taxus yunnanensis has not been systematically character...
In Vitro Effects of Amygdalin on Proliferation and Apoptosis in SH-SY5Y Neuroblastoma Cells [0.03%]
苦杏仁苷对神经母细胞瘤SH-SY5Y细胞增殖和凋亡的体外影响
Tuba Gül,Mücahit Seçme
Tuba Gül
Background and objectives: Neuroblastoma represents the most common extracranial solid tumor in childhood and is associated with a poor prognosis in high-risk cases. Amygdalin, a naturally occurring cyanogenic glycoside, ...
Lysimachia christinae Hance Extract Mitigates Kidney Stone Formation: Association with NOX2/ROS Axis Modulation and Ferroptosis [0.03%]
*Lysimachia christinae* Hance提取物可减轻肾结石形成：与调节NOX2/ROS轴和铁死亡有关
Lian Xia,Zhaoguo Zhou,Chen Luo et al.
Lian Xia et al.
Kidney stone disease is a common urinary system disorder with a continuously rising global incidence, posing a major public health challenge. As a classic traditional Chinese medicine for the treatment of kidney stones, Lysimachia christina...
Estrogen Replacement Therapy in Ovariectomized Rats: Complementary Roles of ER and GPR30 in Alleviating Depressive-like Behavior [0.03%]
卵巢切除大鼠雌激素替代治疗：ER和GPR30在改善类似抑郁行为中的协同作用
Siyi He,Zhongyu Ren,Lan Wu et al.
Siyi He et al.
Women are twice as likely to suffer from major depressive disorder (MDD). The underlying mechanism between estrogen and depression is still unknown. We used ovariectomized rats to simulate menopausal status and established a depression mode...
Deciphering the Shared Mechanisms Underlying the Effects of Osthole on the Inflammation-Cancer Axis: An Integrative Network Pharmacology and Molecular Dynamics Study [0.03%]
解读欧洛石防炎抗癌效应的共通机制：整合网络药理学和分子动力学研究
Peng Tang,Jing Yang,Haoyi Wang et al.
Peng Tang et al.
The persistence of an immunosuppressive microenvironment remains a formidable challenge for cancer immunotherapy, particularly in tumors with immune-excluded or immune-desert phenotypes. Increasing evidence indicates that chronic inflammati...
Evaluation of the Systemic Inflammatory Landscape and C1q/TNF-Related Protein Profiles in Facial Paralysis [0.03%]
面瘫的全身性炎症谱系及C1q/肿瘤坏死因子相关蛋白谱系评估
Ergin Bilgin,Deniz Baklacı,Tuba Çandar
Ergin Bilgin
Background and Objectives: The primary objective of this study was to elucidate the diagnostic significance of systemic inflammatory indices and C1q/TNF-related proteins (CTRP3 and CTRP5) in acute facial paralysis, with a focus on identifyi...
Systemic Cytokine Patterns and Histologic Disease Spectrum in Inflammatory Bowel Disease [0.03%]
炎症性肠病的全身细胞因子谱型及其病理学表现分布状况
Nikolaos Martinos,Christos Kroupis,Maria Gypari et al.
Nikolaos Martinos et al.
Background/objectives: Histologic mucosal healing is an increasingly recognized therapeutic target in inflammatory bowel disease (IBD), yet reliable non-invasive correlates remain limited. This study aimed to evaluate cir...
Nocturnal Melatonin Amplitude Collapse Is Associated with Age-Independent Convergence of Microbiome and Glymphatic Biomarkers [0.03%]
褪黑素夜间振幅衰减与年龄无关的微生物组和脑淋巴标记物趋同现象有关
Alexandre Tavartkiladze,Levan Tavartkiladze,Russel J Reiter et al.
Alexandre Tavartkiladze et al.
Circadian desynchronization is increasingly linked to metabolic, immune, neurocognitive, and oncological disease, but integrated clinical phenotyping across endocrine, microbiome, metabolic, and neuroimaging domains remains limited. We cond...
Molecular Profiling of Soil-Derived Bacillus subtilis and Bacillus paralicheniformis: Evaluation of Anticancer and Antibacterial Efficacy Against Gastrointestinal Pathogens [0.03%]
土壤来源的枯草芽孢杆菌和巴氏芽孢杆菌分子特征分析：对胃肠病原菌抗癌及抗菌功效评估
Rida-E-Zainab Kayani,Komal Aman,Tajamul Hussain et al.
Rida-E-Zainab Kayani et al.
Background: Microbial derivatives are pivotal in research because of their structural heterogeneity and diverse biological significance, including antitumor and antimicrobial activities. Aims and Objectives: This study aimed to evaluate the...
Expression and Promoter Methylation of the Genes Encoding the Mitochondrial and Cytosolic Forms of Fumarase in Sunflower (Helianthus annuus L.) Leaves Depending on Light Regime and Salinity [0.03%]
光周期和盐度对向日葵叶片线粒体和胞浆苹果酸酶基因表达及启动子甲基化的影响
Oksana V Sazonova,Dmitry N Fedorin,Alexander T Eprintsev et al.
Oksana V Sazonova et al.
The expression of two genes, Fum1 and Fum2, encoding the mitochondrial and cytosolic forms of fumarase (EC 4.2.1.2); the methylation of individual CpGs of their promoters; and fumarase activity were studied in sunflower (Helianthus annuus L...