Correction to: A window-of-opportunity trial of the CXCR1/2 inhibitor reparixin in operable HER-2-negative breast cancer [0.03%]
Correction to：乳腺癌CXCR1/2抑制剂Reparixin窗口试验一期——HER-2阴性的可手术病人的免疫原性
Lori J Goldstein,Raymond P Perez,Denise Yardley et al.
Lori J Goldstein et al.
An amendment to this paper has been published and can be accessed via the original article.
Published Erratum
Breast cancer research : BCR. 2020 May 20;22(1):52. DOI:10.1186/s13058-020-01294-7 2020
Antitumor activity of Z-endoxifen in aromatase inhibitor-sensitive and aromatase inhibitor-resistant estrogen receptor-positive breast cancer [0.03%]
阿那曲唑敏感及耐药的雌激素受体阳性乳腺癌中Z-恩杂曲辛的抗肿瘤活性研究
Swaathi Jayaraman,Xiaonan Hou,Mary J Kuffel et al.
Swaathi Jayaraman et al.
Background: The tamoxifen metabolite, Z-endoxifen, demonstrated promising antitumor activity in endocrine-resistant estrogen receptor-positive (ER+) breast cancer. We compared the antitumor activity of Z-endoxifen with ta...
Henri-Philippe Konan,Loay Kassem,Soleilmane Omarjee et al.
Henri-Philippe Konan et al.
Background: Alterations in estrogen and progesterone signaling, via their respective receptors, estrogen receptor alpha (ERα) and progesterone receptor (PR), respectively, are largely involved in the development of breas...
Clinical and functional significance of tumor/stromal ATR expression in breast cancer patients [0.03%]
ATR在乳腺癌患者肿瘤/间质中的临床和功能意义
Mysoon M Al-Ansari,Maher Al-Saif,Maria Arafah et al.
Mysoon M Al-Ansari et al.
Background: Most breast cancer-associated fibroblasts (CAFs) are active and important cancer-promoting cells, with significant impact on patient prognosis. Therefore, we investigated here the role of the protein kinase AT...
Simultaneous targeting of HER family pro-survival signaling with Pan-HER antibody mixture is highly effective in TNBC: a preclinical trial with PDXs [0.03%]
一种针对HER家族促存活信号的泛HER抗体混合物在TNBC中的药效学试验：使用PDX进行的一项临床前试验
Tejaswini P Reddy,Dong S Choi,Ann C Anselme et al.
Tejaswini P Reddy et al.
Background: The human epidermal growth factor receptor (HER) family, notably EGFR, is overexpressed in most triple-negative breast cancer (TNBC) cases and provides cancer cells with compensatory signals that greatly contr...
Tumour-infiltrating lymphocytes and response to neoadjuvant letrozole in patients with early oestrogen receptor-positive breast cancer: analysis from a nationwide phase II DBCG trial [0.03%]
肿瘤浸润淋巴细胞与早期雌激素受体阳性乳腺癌新辅助来曲唑治疗的应答：全国多中心Ⅱ期DBCG临床试验分析
Signe Korsgaard Skriver,Maj-Britt Jensen,Ann Soegaard Knoop et al.
Signe Korsgaard Skriver et al.
Background: The presence of tumour-infiltrating lymphocytes (TILs) is associated with response to neoadjuvant chemotherapy among patients with triple-negative and HER2-positive breast cancer. However, the significance of ...
Association of TILs with clinical parameters, Recurrence Score® results, and prognosis in patients with early HER2-negative breast cancer (BC)-a translational analysis of the prospective WSG PlanB trial [0.03%]
肿瘤浸润淋巴细胞与临床参数、Recurrence Score®结果及早期HER2阴性乳腺癌患者的预后之间的关系——WSG PlanB前瞻性试验的转化分析
Cornelia Kolberg-Liedtke,Oleg Gluz,Fred Heinisch et al.
Cornelia Kolberg-Liedtke et al.
Background: The presence of tumor-infiltrating lymphocytes has been associated with prognosis and chemotherapy response, particularly in high-risk breast cancer subtypes. There is limited data so far as to (i) how tumor-i...
Frequency and spectrum of PIK3CA somatic mutations in breast cancer [0.03%]
乳腺癌中PIK3CA基因体细胞突变的频率及类型分布特征分析
Olga Martínez-Sáez,Nuria Chic,Tomás Pascual et al.
Olga Martínez-Sáez et al.
Purpose: The therascreen PIK3CA mutation assay and the alpha-specific PI3K inhibitor alpelisib are FDA-approved for identifying and treating patients with advanced PIK3CA-mutated (PIK3CAmut) breast cancer (BC). However, i...
Functional evaluation of five BRCA2 unclassified variants identified in a Sri Lankan cohort with inherited cancer syndromes using a mouse embryonic stem cell-based assay [0.03%]
基于小鼠胚胎干细胞的评估BRCA2未知变异的功能遗传学研究
Nirmala Sirisena,Kajal Biswas,Teresa Sullivan et al.
Nirmala Sirisena et al.
Next-generation sequencing of Sri Lankan families with inherited cancer syndromes resulted in the identification of five BRCA2 variants of unknown clinical significance. Interpreting such variants poses significant challenges for both clini...
Insulin resistance contributes to racial disparities in breast cancer prognosis in US women [0.03%]
胰岛素抵抗导致美国女性乳腺癌预后种族差异
Emily J Gallagher,Kezhen Fei,Sheldon M Feldman et al.
Emily J Gallagher et al.
Background: Racial disparities in breast cancer survival between Black and White women persist across all stages of breast cancer. The metabolic syndrome (MetS) of insulin resistance disproportionately affects more Black ...
Multicenter Study
Breast cancer research : BCR. 2020 May 12;22(1):40. DOI:10.1186/s13058-020-01281-y 2020