Prevalence of germline BRCA mutations in HER2-negative metastatic breast cancer: global results from the real-world, observational BREAKOUT study [0.03%]
全球BRCA基因突变负面HER2转移性乳腺癌的发病率：来自真实世界观察研究BREAKOUT的研究结果
Joyce O&#x;Shaughnessy,Christine Brezden-Masley,Marina Cazzaniga et al.
Joyce O&#x;Shaughnessy et al.
Background: The global observational BREAKOUT study investigated germline BRCA mutation (gBRCAm) prevalence in a population of patients with human epidermal growth factor receptor 2 (HER2)-negative metastatic breast cance...
Gemcitabine as adjuvant chemotherapy in patients with high-risk early breast cancer-results from the randomized phase III SUCCESS-A trial [0.03%]
吉西他滨作为高危早期乳腺癌患者的辅助化疗药物-SUCCESS-A随机III期试验的结果
Amelie de Gregorio,Lothar Häberle,Peter A Fasching et al.
Amelie de Gregorio et al.
Background: When chemotherapy is indicated in patients with early breast cancer, regimens that contain anthracyclines and taxanes are established standard treatments. Gemcitabine has shown promising effects on the respons...
Circulating growth factor concentrations and breast cancer risk: a nested case-control study of IGF-1, IGFBP-3, and breast cancer in a family-based cohort [0.03%]
循环生长因子浓度与乳腺癌风险之间的关系：IGF-1，IGFBP-3和家族队列中乳腺癌的嵌套病例对照研究
Kelsey R Monson,Mandy Goldberg,Hui-Chen Wu et al.
Kelsey R Monson et al.
Background: Insulin-like growth factor 1 (IGF-1) and binding protein 3 (IGFBP-3) are associated with breast cancer in women at average risk of cancer. Less is known whether these biomarkers also predict risk in women with...
Correction to: Trastuzumab-induced upregulation of a protein set in extracellular vesicles emitted by ErbB2-positive breast cancer cells correlates with their trastuzumab sensitivity [0.03%]
纠正是：曲妥珠单抗诱导ErbB2阳性乳腺癌细胞分泌的外泌蛋白组上调与它们对曲妥珠单抗的敏感性相关
Arik Drucker,Byong Hoon Yoo,Iman Aftab Khan et al.
Arik Drucker et al.
An amendment to this paper has been published and can be accessed via the original article.
Published Erratum
Breast cancer research : BCR. 2020 Oct 22;22(1):110. DOI:10.1186/s13058-020-01358-8 2020
Haplotype analysis of the internationally distributed BRCA1 c.3331_3334delCAAG founder mutation reveals a common ancestral origin in Iberia [0.03%]
国际分布的BRCA1 c.3331_3334delCAAG始发突变的单倍型分析显示其在伊比利亚有共同的祖先来源
Anna Marie De Asis Tuazon,Paul Lott,Mabel Bohórquez et al.
Anna Marie De Asis Tuazon et al.
Background: The BRCA1 c.3331_3334delCAAG founder mutation has been reported in hereditary breast and ovarian cancer families from multiple Hispanic groups. We aimed to evaluate BRCA1 c.3331_3334delCAAG haplotype diversity...
Inter-tumor genomic heterogeneity of breast cancers: comprehensive genomic profile of primary early breast cancers and relapses [0.03%]
乳腺癌的瘤间基因组异质性：原发早期乳腺癌和复发癌的全面基因组特征
Caterina Fumagalli,Alberto Ranghiero,Sara Gandini et al.
Caterina Fumagalli et al.
Background: The breast cancer genome dynamically evolves during malignant progression and recurrence. We investigated the genomic profiles of primary early-stage breast cancers and matched relapses to elucidate the molecu...
Incidence of hypothyroidism after treatment for breast cancer-a Danish matched cohort study [0.03%]
乳腺癌治疗后甲状腺功能减退的发生率-一项丹麦匹配队列研究
Anne Mette Falstie-Jensen,Buket Ö Esen,Anders Kjærsgaard et al.
Anne Mette Falstie-Jensen et al.
Background: Breast cancer survivors (BCS) may have increased risk of hypothyroidism, but risk according to treatment modality is unclear. We estimated the incidence of hypothyroidism in women with breast cancer, and accor...
Trastuzumab-induced upregulation of a protein set in extracellular vesicles emitted by ErbB2-positive breast cancer cells correlates with their trastuzumab sensitivity [0.03%]
曲妥珠单抗诱导ErbB2阳性乳腺癌细胞释放的胞外囊泡中一组蛋白质的上调与它们对曲妥珠单抗的敏感性相关
Arik Drucker,Byong Hoon Yoo,Iman Aftab Khan et al.
Arik Drucker et al.
Background: ErbB2/HER2 oncoprotein often drives breast cancers (BCs) which are treated with the anti-ErbB2 antibody trastuzumab. The efficacy of trastuzumab-based metastatic BC therapies is routinely assessed by imaging s...
Association between indicators of systemic inflammation biomarkers during puberty with breast density and onset of menarche [0.03%]
青春期全身炎症生物标志物与乳腺密度及月经初潮发生之间的关联研究
Karin B Michels,Kristen Keller,Ana Pereira et al.
Karin B Michels et al.
Background: Systemic inflammation may play a role in shaping breast composition, one of the strongest risk factors for breast cancer. Pubertal development presents a critical window of breast tissue susceptibility to exog...
Sunitinib facilitates metastatic breast cancer spreading by inducing endothelial cell senescence [0.03%]
舒尼替尼通过诱导内皮细胞衰老促进乳腺癌转移
Denian Wang,Fei Xiao,Zhongxue Feng et al.
Denian Wang et al.
Background: Sunitinib, a receptor tyrosine kinase (RTK) inhibitor that targets multiple receptors such as vascular endothelial growth factor receptors (VEGFRs), was approved for cancer treatment in 2006. However, it was u...