Distinct genetic profiles of obesity have different effects on breast cancer risk: leveraging Mendelian randomisation to interrogate causal pathways and identify mediating proteins [0.03%]
肥胖的不同遗传特征对乳腺癌风险的影响不同：利用孟德尔随机化研究因果途径并识别中介蛋白质
Marina Isabel Marchal,Pascal M Mutie,Tayebeh Azimi et al.
Marina Isabel Marchal et al.
Association between metabolic dysfunction-associated steatotic liver disease and breast cancer risk in Korean women: a nationwide population-based cohort study [0.03%]
代谢功能紊乱相关肝脂肪性肝病与韩国女性乳腺癌风险的关系：基于全国人口的队列研究
Jin Ah Lee,Hye Sun Lee,Soyoung Jeon et al.
Jin Ah Lee et al.
Recreational physical activity and biomarkers of breast cancer risk in a cohort of adolescent girls [0.03%]
一项针对青春期女性的研究：娱乐性体育活动与乳腺癌生物标志物的关系
Rebecca D Kehm,Lothar Lilge,E Jane Walter et al.
Rebecca D Kehm et al.
Molecular subtypes of breast cancer in Jamaican women: high prevalence of triple-negative and HER2 + disease [0.03%]
牙买加女性的乳腺癌分子亚型：三阴性和HER2+疾病的高发率
Richard Shaw,Derria Cornwall,Simone Badal et al.
Richard Shaw et al.
Premenopausal serum midkine levels and risk of estrogen receptor positive breast cancer: a prospective, nested case-control study [0.03%]
绝经前血清中脑因子水平与雌激素受体阳性乳腺癌发病风险的前瞻性病例对照研究
Pengze Yan,Fen Wu,Yelena Afanasyeva et al.
Pengze Yan et al.
Background: Midkine is a heparin-binding growth factor that is overexpressed in most human malignancies, including breast cancer. While elevated midkine levels have been associated with tumor progression and aging, its ro...
The spatial immune landscape predicts outcome and reveals the central role of tumor-associated macrophages in inflammatory breast cancer biology [0.03%]
空间免疫图谱可预测预后并揭示肿瘤相关巨噬细胞在炎性乳腺癌生物学中的核心作用
Christophe Van Berckelaer,Steven Van Laere,Chloé Vermeulen et al.
Christophe Van Berckelaer et al.
Background: Inflammatory breast cancer (IBC) is a rare but aggressive subtype of breast cancer characterized by rapid progression and poor prognosis. Despite its distinct clinical presentation and molecular features, the ...
Νovel methylation biomarkers in liquid biopsy and classifying biosignatures for the clinical management of breast cancer [0.03%]
液体活检中的新型甲基化生物标志物及乳腺癌临床管理的生物标志物分类
Maria Panagopoulou,Maria A Papadaki,Makrina Karaglani et al.
Maria Panagopoulou et al.
Background: Breast Cancer (BrCa) remains a devastating disease presenting emerging needs for effective management. Recently, epigenetic biomarkers are assessed in liquid biopsy for diagnostic and prognostic applications. ...
Experimental evaluation of dermal lymphatics in preservation of lymphatic function [0.03%]
保存淋巴功能的真皮淋巴管实验评估
Luci Hulsman,Ganesh Mohan,Angad S Sidhu et al.
Luci Hulsman et al.
Background: Secondary lymphedema is characterized by limb swelling following lymphatic disruption. This results in decreased lymph flow through the collecting ducts and dermal backflow in the subdermal lymphatics. The rol...
BHLHE22, targeted by deubiquitinating enzyme OTUD3, exerts an antitumor role in triple-negative breast cancer progression via transcriptionally inhibiting CDT1 [0.03%]
泛素蛋白连接酶OTUD3靶向调控BHLHE22抑制三阴性乳腺癌进展中的转录作用机制研究
Lei Jiang,Junnan Xu,Cui Jiang et al.
Lei Jiang et al.
Background: Basic helix-loop-helix family, member e22 (BHLHE22), a basic helix loop helix transcription factor family member, functions vary in different types of cancer. Currently, its function in triple-negative breast ...
IFI16/IFI202 blockade suppresses tumor growth through CD8+ T-cell-mediated immunity [0.03%]
IFI16 / IFI202 阻断通过 CD8 +T 细胞介导的免疫抑制肿瘤生长
Ga Young Lim,Na-Lee Ka,Seung-Su Kim et al.
Ga Young Lim et al.