Programmed death ligand 1 protein expression, histological tumour differentiation and intratumoural heterogeneity in pulmonary adenocarcinoma [0.03%]
肺腺癌中程序性死亡配体-1蛋白表达、组织学肿瘤分化及瘤内异质性研究
Vladimír Tancoš,Marián Grendár,Anna Farkašová et al.
Vladimír Tancoš et al.
Intratumoural heterogeneity of pulmonary adenocarcinoma challenges the accurate interpretation of programmed death ligand 1 (PD-L1) immunohistochemistry, which is the only validated predictive marker for successful anti-PD-1/PD-L1 immunothe...
Clinicopathological and molecular analysis of SIRT7 in hepatocellular carcinoma [0.03%]
SIRT7在肝细胞癌中的临床病理和分子分析
Masae Yanai,Morito Kurata,Yutaka Muto et al.
Masae Yanai et al.
Sirtuin 7 (SIRT7) is a NAD+ (nicotinamide adenine dinucleotide) dependent deacetylase that is reported to contribute to tumour growth and invasion by selectively acting on histone H3K18. It is overexpressed in several cancers including hepa...
Assessment of European Society of Paediatric Gastroenterology Hepatology and Nutrition (ESPGHAN) guidelines in an Australian paediatric population [0.03%]
评估欧洲儿科胃肠病、 hepatology 和营养学协会( ESPGHAN )指南在澳大利亚儿童中的应用情况
Grace Thompson,Zubin Grover,Richard Loh et al.
Grace Thompson et al.
Coeliac disease (CD) diagnosis is based on clinical assessment, detection of specific autoantibodies and histological examination of small intestinal biopsies. The European Society of Paediatric Gastroenterology Hepatology and Nutrition (ES...
The impact of indirect immunofluorescence screening dilution on the positivity of gastric parietal cell antibodies [0.03%]
间接免疫荧光筛选稀释度对胃壁细胞抗体阳性率的影响
Louise Wienholt,Emma Dawson,Loriza Khan et al.
Louise Wienholt et al.
Frequent occurrence of low-level positive autoantibodies in chronic hepatitis C [0.03%]
慢性C型肝炎患者低滴度自身抗体的出现及其临床意义
Pooja Deshpande,Christine Bundell,Elizabeth McKinnon et al.
Pooja Deshpande et al.
Evidence of autoimmune disease associated with hepatitis C virus (HCV)-infection has important clinical implications. A systematic profile of these autoantibodies in relevant clinical cohorts relative to healthy controls is needed to better...
Knowledge at what cost? An audit of the utility of panfungal PCR performed on bronchoalveolar lavage fluid specimens at a tertiary mycology laboratory [0.03%]
何价求真菌?一项关于三级真菌参考实验室支气管肺泡灌洗标本泛真菌PCR检测的效益审计研究
Katherine Garnham,Catriona L Halliday,Jen Kok et al.
Katherine Garnham et al.
The diagnostic utility and costs of panfungal PCR assays for invasive fungal disease (IFD) from bronchoalveolar lavage fluid (BALF) specimens are incompletely defined. In a retrospective audit, panfungal PCR results from 2014-2018 were matc...
The effect of miR-223 on cellular behaviour in non-5q myelodysplastic syndromes through targeting RPS14 [0.03%]
miR-223通过靶向RPS14影响非5q型骨髓增生异常综合征细胞行为的作用机制研究
Yanbo Nie,Shixuan Wang,Yalan Yu et al.
Yanbo Nie et al.
Myelodysplastic syndromes (MDS) are characterised by impaired haematopoiesis and a high risk of leukaemic transformation. A decrease in RPS14 expression in non-5q MDS patients was confirmed by immunohistochemical analyses of MDS bone marrow...
Hybrid sclerosing epithelioid fibrosarcoma/low grade fibromyxoid sarcoma arising in the small intestine with distinct HEY1-NCOA2 gene fusion [0.03%]
具有特殊HEY1-NCOA2基因融合的小肠杂交硬化上皮样纤维肉瘤/低级别肌纤维母细胞瘤一例报告
Khaled A Murshed,Adham Ammar
Khaled A Murshed
Validation of phospholipase A2 receptor direct immunofluorescence staining in the diagnosis of primary membranous glomerulonephritis [0.03%]
磷脂酶A2受体直接免疫荧光染色在原发性膜性肾病诊断中的验证研究
Pei Dai,David Campbell,Suzanne Culican et al.
Pei Dai et al.
Distinguishing between primary and secondary subtypes of membranous glomerulonephritis (MGN) is critical for its clinical management. We prospectively compared direct immunofluorescence (DIF) staining for phospholipase A2 receptor (PLA2R) o...
Large B-cell lymphoma presenting primarily in bone marrow is frequently associated with haemophagocytic lymphohistiocytosis and has distinct cytogenetic features [0.03%]
以骨髓受累为主的弥漫性大B细胞淋巴瘤常合并噬血细胞性淋巴组织细胞增生症并具有独特的细胞遗传学特征
Ching-Fen Yang,Liang-Tsai Hsiao,Hsin-Yi Chang et al.
Ching-Fen Yang et al.
The criteria for primary bone marrow large B-cell lymphoma (PBMLBCL) have not yet been clearly established. We aimed to investigate the clinicopathological features of PBMLBCLs (27 cases) and large B-cell lymphomas (LBCLs) with secondary ma...