R J Fix Sr,J M Rowe,B C McConnell
R J Fix Sr
Laboratories that once viewed automation as an expensive luxury are now looking to automation as a solution to increase sample throughput, to help ensure data integrity and to improve laboratory safety. The question is no longer, 'Should we...
An improved automated immunoassay for C-reactive protein on the Dimension clinical chemistry system [0.03%]
Dimension系统CRP全自动免疫测定的改进
T Q Wei,S Kramer,V P Chu et al.
T Q Wei et al.
Recent clinical data indicate that the measurement of the concentration of C-reactive protein (CRP) requires a higher sensitivity and wider dynamic range than most of the current methods can offer. Our goal was to develop a totally automate...
I Mahmud,D Kim
I Mahmud
In an environment where cost, timeliness, and quality drives the business, it is essential to look for answers in technology where these challenges can be met. In the Novartis Pharmaceutical Quality Assurance Department, automation and robo...
J Ormand,J Bruner,L Birkemo et al.
J Ormand et al.
In the latter part of the 1990s, many companies have worked to foster a 'matrix' style culture through several changes in organizational structure. This type of culture facilitates communication and development of new technology across orga...
A fully automated liquid-liquid extraction system utilizing interface detection [0.03%]
一种利用界面检测的全自动液液萃取系统
E Maslana,R Schmitt,J Pan
E Maslana
The development of the Abbott Liquid-Liquid Extraction Station was a result of the need for an automated system to perform aqueous extraction on large sets of newly synthesized organic compounds used for drug discovery. The system utilizes ...
The Zymark BenchMate. A compact, fully-automated solution-phase reaction work-up facility for multiple parallel synthesis [0.03%]
Zymark BenchMate平行溶液相合成多功能工作站
G A Hamlin
G A Hamlin
The rapid growth of multiple parallel synthesis in our laboratories has created a demand for a robust, easily accessed automated system for solution-phase reaction work-up, since the manual work-up of large numbers of small-scale reactions ...
The planning and establishment of a sample preparation laboratory for drug discovery [0.03%]
药物发现样品前处理实验室的建设与运行
C Dufresne
C Dufresne
Nature has always been a productive source of new drugs. With the advent of high-throughput screening, it has now become possible to rapidly screen large sample collections. In addition to seeking greater diversity from natural product sour...
M Entzeroth,B Chapelain,J Guilbert et al.
M Entzeroth et al.
High throughput screening has significantly contributed to advances in drug discovery. The great increase in the number of samples screened has been accompanied by increases in costs and in the data required for the investigated compounds. ...
Managing laboratory automation: integration and informatics in drug discovery [0.03%]
药物发现中的实验室自动化管理：整合与信息技术
C J Manly
C J Manly
Drug discovery today requires the focused use of laboratory automation and other resources in combinatorial chemistry and high-throughput screening (HTS). The ultimate value of both combinatorial chemistry and HTS technologies and the lasti...
Peter B Stockwell
Peter B Stockwell
To attend or not to attend, that is the question. The Pittsburgh Conference continues to pose this conundrum to conferees and exhibitors alike. This year's conference was the first to be presented without a set of paper abstracts-a good thi...