Hereditary transthyretin amyloidosis: molecular basis and therapeutical strategies [0.03%]
遗传性转甲状腺素蛋白淀粉样变性的分子基础和治疗策略
Maria João Mascarenhas Saraiva
Maria João Mascarenhas Saraiva
Transthyretin (TTR) is a transport protein for thyroid hormones and vitamin A and might have an important role in the nervous system. However, TTR can undergo a conformational change and form amyloid fibrils, in both acquired and hereditary...
Megan P Hitchins,Gudrun E Moore
Megan P Hitchins
Each somatic cell of the human body contains 46 chromosomes consisting of two sets of 23; one inherited from each parent. These chromosomes can be categorised as 22 pairs of autosomes and two sex chromosomes; females are XX and males are XY...
W Nicol Keith,Alan Bilsland,T R Jeffry Evans et al.
W Nicol Keith et al.
The management of malignant disease remains one of the most challenging areas of modern medicine. The lifetime risk of developing cancer in the western world is estimated to be as high as 1 in 3. Traditionally, surgery, chemotherapy and rad...
Molecular organisation of cell-matrix contacts: essential multiprotein assemblies in cell and tissue function [0.03%]
细胞-基质接触的分子结构:细胞和组织功能的基本多蛋白复合物
Josephine Clare Adams
Josephine Clare Adams
The adhesion of cells to their surrounding extracellular matrix has vital roles in embryonic development, inflammatory responses, wound healing and adult tissue homeostasis. Cells attach to extracellular matrix by specific cell-surface rece...
D J Davidson,J R Dorin
D J Davidson
T-cell receptor binding kinetics in T-cell development and activation [0.03%]
T细胞受体结合动力学在T细胞发育和活化中的作用
N R Gascoigne,T Zal,S M Alam
N R Gascoigne
C Boucheix,G H Duc,C Jasmin et al.
C Boucheix et al.