A Garrido,I Martínez de Toda,E Díaz Del Cerro et al.
A Garrido et al.
Immune system aging, a process known as immunosenescence, involves a striking rearrangement affecting all immune cells, resulting in an increased rate of infections and a major incidence of autoimmune diseases and cancer. Nonetheless, diffe...
Obesity-related genomic instability and altered xenobiotic metabolism: possible consequences for cancer risk and chemotherapy [0.03%]
与肥胖相关的基因组不稳定和外来物质代谢改变：对癌症风险和化疗的可能影响
Ezgi Eyluel Bankoglu,Helga Stopper
Ezgi Eyluel Bankoglu
The increase in the prevalence of obesity has led to an elevated risk for several associated diseases including cancer. Several studies have investigated the DNA damage in human blood samples and showed a clear trend towards increased DNA d...
Mohammad Hossein Akhbari,Zahra Zafari,Mohsen Sheykhhasan
Mohammad Hossein Akhbari
Colorectal cancer (CRC) is a common type of cancer and the second leading cause of cancer-related deaths worldwide. Competing endogenous RNAs (ceRNAs) that contain microRNA response elements (MREs) are involved in CRC progression. They can ...
Relevance of emerging metabolomics-based biomarkers of prostate cancer: a systematic review [0.03%]
基于代谢组学的前列腺癌生物标志物的新研究：系统性综述
Navneeta Bansal,Manoj Kumar,S N Sankhwar et al.
Navneeta Bansal et al.
Prostate cancer (PC) presents great challenges in early diagnosis and often leads to unnecessary invasive procedures as well as over diagnosis and treatment, thus highlighting the need for promising early diagnostic biomarkers. The aim of t...
The potential role of FNDC5/irisin in various liver diseases: awakening the sleeping beauties [0.03%]
FNDC5/irisin在各种肝脏疾病中的潜在作用：唤醒睡美人
Xiaoyu Wang,Lihong Mao,Chaoqun Li et al.
Xiaoyu Wang et al.
Fibronectin type III domain-containing protein 5 (FNDC5) is a transmembrane protein and the precursor of irisin, which serves as a systemic exerkine/myokine with multiple origins. Since its discovery in 2012, this hormone-like polypeptide h...
Fang-Fang Dai,Min Hu,Yu-Wei Zhang et al.
Fang-Fang Dai et al.
Pregnancy is a complex biological process. The establishment and maintenance of foetal-maternal interface are pivotal events. Decidual immune cells and inflammatory cytokines play indispensable roles in the foetal-maternal interface. The di...
Non-invasive molecular biomarkers for predicting outcomes of micro-TESE in patients with idiopathic non-obstructive azoospermia [0.03%]
无创分子生物标志物预测特发性NOA患者微睾切开取精术结局的研究
Dongdong Tang,Kuokuo Li,Xiaojin He et al.
Dongdong Tang et al.
Non-obstructive azoospermia (NOA), the most severe type of male infertility, affects approximately 1% of men worldwide. However, the aetiology of most NOA cases is not definite, that is defined as idiopathic NOA (INOA), posing a clinical co...
Chun Li,Lucy Wiseman,Ene Okoh et al.
Chun Li et al.
Ionising radiotherapy is a well-established, effective cancer treatment modality, whose efficacy has improved with the application of newer technological modalities. However, patient outcomes are governed and potentially limited by aspects ...
Reduced melatonin levels may facilitate glioblastoma initiation in the subventricular zone [0.03%]
褪黑素水平下降可能会促进侧脑室区胶质母细胞瘤的产生
Majid Ghareghani,Kazem Zibara,Russel J Reiter et al.
Majid Ghareghani et al.
There is increasing evidence that glioblastoma, a highly aggressive brain tumour, originates from a neural stem cell (NSC) located in the subventricular zone (SVZ) of the lateral cerebral ventricle. Using the most advanced in vivo imaging t...
Immunopathogenesis of patients with COVID-19: from the perspective of immune system 'evolution' and 'revolution' [0.03%]
从免疫系统“进化”与“革命”的视角看COVID-19患者的免疫病理机制
Dan Lv,Bai Hu,Xingguang Lin et al.
Dan Lv et al.
The pandemic caused by severe acute respiratory syndrome coronavirus 2 is sweeping the world, threatening millions of lives and drastically altering our ways of living. According to current studies, failure to either activate or eliminate i...