Computational Modelling of Novelty Detection in the Mismatch Negativity Protocols and Its Impairments in Schizophrenia [0.03%]
新颖性检测的计算模型及其在精神分裂症中的缺陷失调现象研究
Ahmed Eissa,Jan Fredrik Kismul,Atle Bråthen Pentz et al.
Ahmed Eissa et al.
The human auditory system rapidly distinguishes between novel and familiar sounds, a process reflected in mismatch negativity (MMN), an electroencephalogram (EEG)-based biomarker of auditory novelty detection. MMN is impaired in psychiatric...
Parietal Alpha-Band Connectivity Tracks Listening Effort in Hearing-Aid Users Under Competing Speech and Noise [0.03%]
听觉助听器使用者在竞争性言语和噪音中聆听努力的顶叶α频段连接性研究
Payam Shahsavari Baboukani,Emina Alickovic,Jan Østergaard et al.
Payam Shahsavari Baboukani et al.
This study examines how the signal-to-noise-interference ratio (SNIR) influences auditory performance and neural responses associated with listening effort (LE). A new dataset was collected from individuals with moderate hearing loss, all f...
Mobile Powerhouses: Mitochondria Transfer via Tunnelling Nanotubes in Brain Health and Neurodegenerative Diseases [0.03%]
线粒体通过穿孔纳米管转移在脑健康和神经退行性疾病中的作用
Anna Henrich,Hannah Scheiblich
Anna Henrich
Mitochondria are central regulators of cellular metabolism, calcium homeostasis and survival. Owing to the brain's exceptional energy demand, mitochondrial dysfunction is tightly linked to neurodegenerative and neuroinflammatory disorders. ...
Postinjury Carnosine Treatment Prevents Neurotrophic Factor Decline in Denervated Muscle and Spinal Cord After Traumatic Injury [0.03%]
创伤性损伤后肉毒碱治疗可防止脱髓鞘肌肉和脊髓神经因子下降
Karolina Kucharova,Tomas Kuruc,Martina Magurova et al.
Karolina Kucharova et al.
Local intraspinal or intramuscular administration of brain-derived or glial cell line-derived neurotrophic factors (BDNF, GDNF) is known to protect neural tissue after traumatic spinal cord injury (SCI). In this study, we investigated wheth...
A Relative Authorship Index: A New Metric for Evaluating Individual Contribution in Scientific Research [0.03%]
一种相对作者指数：衡量科学研究中个人贡献的新指标
Francesco Siano,Mariella Segreti,Pierpaolo Pani et al.
Francesco Siano et al.
This study presents the relative authorship index (RAI), a novel metric designed to address the limitations of traditional bibliometric indicators, such as publication counts, citation numbers, and the h-index, by correcting for authorship ...
Corticocerebellar Effective Connectivity During Adapting to vs. Ignoring Delayed Visual Movement Feedback [0.03%]
适应与忽视延迟视觉运动反馈时的皮层小脑有效连接性
Zhenyu Wang,Jakub Limanowski
Zhenyu Wang
Internal models in the brain may enable flexible action control by calculating estimates of the body's state and predictions of the sensory consequences that its actions will produce. These processes are thought to be implemented by interac...
Cortical Network Disruption and Transcriptional Profiles in Poststroke Aphasia: A Functional Connectivity Gradient Approach [0.03%]
卒中失语症的皮层网络破坏和转录组特征：功能连接梯度方法
Li Wang,Jia Yang,Rubin Yan et al.
Li Wang et al.
Poststroke aphasia significantly impacts the quality of life in older adults, yet the underlying neural mechanisms linking macro-scale network hierarchy and micro-scale molecular architecture remain unclear. This study investigated alterati...
Postsynaptic Induction and Presynaptic Expression of Long-Term Potentiation at Excitatory Synapses on Layer 2/3 VIP Interneurons in the Somatosensory Cortex [0.03%]
感觉皮层第2/3层VIP中间神经元兴奋性突触的长时程增强的后突触诱导和前突触表达
Karolina Bogaj,Joanna Urban-Ciecko
Karolina Bogaj
Synaptic transmission between specific connection motifs undergoes plastic changes during the learning process; however, the exact mechanisms underlying synaptic plasticity are still under intense investigation. Long-term potentiation (LTP)...
Extracellular Diffusion of Tau Protein Is Slower Than Similar-Sized IgG Protein and Dextran Polysaccharide in Entorhinal Cortex but Not in Prefrontal Cortex [0.03%]
tau蛋白在内侧颞叶外囊中的细胞外扩散速率低于相似大小的IgG蛋白和右旋糖酐多糖，而在前额叶中两者扩散速率无差异
Matthew Rubin,Aditi Naik-Talapadatur,Petra Majerova et al.
Matthew Rubin et al.
In brain's extracellular space (ECS), proteins form an important part of endogenous macromolecular traffic. Each protein has unique diffusion characteristics governed by its size and, potentially, by charge-based interactions with extracell...
Region and Cell-Selective Induction of Zbtb16/Plzf by Multiple Stressors in the Adult Murine Hypothalamus [0.03%]
成人小鼠下丘脑中应激诱导Zbtb16/PLZF的区域和细胞选择性
Mina Roueinfar,Pardis Mohammadzadeh,Luke A Schwerdtfeger et al.
Mina Roueinfar et al.
Stress activates the hypothalamic-pituitary-adrenal (HPA) axis, a neuroendocrine system that regulates responses related to feeding, reproduction, and aggression, among other homeostatic functions. Stressors significantly impact gene expres...