Freezing of Gait Levodopa Response Pattern in Parkinson's Disease Provides Clues to Pathophysiology [0.03%]
帕金森病冻结步态对左旋多巴的反应模式为病理生理学提供了线索
Stewart A Factor,David Weinshenker,Jeanne Powell et al.
Stewart A Factor et al.
Freezing of gait (FOG) is a common and enigmatic feature of Parkinson's disease (PD) because of its episodic and unpredictable nature. It is now clear that FOG is not a monolithic phenomenon but instead exhibits substantial heterogeneity ac...
Cognitive Flexibility and Bilingual Language Switching: An fMRI Meta-Analysis [0.03%]
认知灵活性与双语语言转换：一项fMRI的meta分析研究
Zhanna Chuikova,Andrei Faber,Jubin Abutalebi et al.
Zhanna Chuikova et al.
Bilinguals' language-switching ability is regulated by language control mechanisms associated with executive control system. Cognitive flexibility (CF), one of the executive functions, is closely linked to language switching. Existing funct...
Improved Motor Neuron Preservation and Axonal Recovery Following Experimental Sciatic Nerve Repair With Heterologous Fibrin Biopolymer [0.03%]
异种纤维蛋白生物聚合物修复坐骨神经的实验研究及神经元保护和轴突恢复的效果评估
Kevin Silva Muller,Felipe Cantore Tibúrcio,Caio Gonçalves do Amaral et al.
Kevin Silva Muller et al.
Peripheral nerve injuries severely impair motor function. Although neurorrhaphy is the gold-standard treatment, recovery is often incomplete. The heterologous fibrin biopolymer (HFB), a nonhuman-derived and biocompatible sealant, has shown ...
Topography of Regional Cerebral GABAA Receptor Availability in Parkinson's Disease Patients With Freezing of Gait [0.03%]
帕金森病伴步态冻结患者区域脑GABA受体可用性地形图分析
Alexander A Hart,Prabesh Kanel,Jaimie Barr et al.
Alexander A Hart et al.
We aimed to explore the relationship between regional gamma-aminobutyric acid (GABAA) receptor availability, measured with [11C]-flumazenil brain positron emission tomography (PET) and freezing of gait in patients with Parkinson's disease. ...
Enhanced Time-Locked Decoding for Spoken Words but Not Environmental Sounds in Natural-Like Auditory Conditions [0.03%]
在类似自然的听觉条件下口语单词的时间锁定解码增强，而非环境声音
Jesper Edström,Anni Nora,Oona Rinkinen et al.
Jesper Edström et al.
Humans are especially sensitive to speech sounds even in complex acoustic environments, but it remains unclear whether speech is tracked differently from other meaningful sounds under such conditions. Magnetoencephalography recordings combi...
Learning Dynamics in Biophysical Spiking Network Models Are Shaped by KCC2/NKCC1 Cotransporter Stoichiometry [0.03%]
KCC2/NKCC1转运蛋白比例决定了生物物理脉冲网络模型中的学习动力学形状
Mohamed Ahmed,Antônio-Carlos Guimarães de Almeida,Antônio Márcio Rodrigues et al.
Mohamed Ahmed et al.
Neuronal chloride homeostasis, governed by the opposing actions of the KCC2 exporter and NKCC1 importer, plays a critical role in regulating excitability and plasticity. While their individual functions are well characterized, the quantitat...
Dopamine Receptor Agonism in the Nucleus Accumbens Shell During Aversive Learning or Memory Retrieval: Differential Effects Depending on the Degree of Sugar Familiarity [0.03%]
伏隔核壳多巴胺受体激动剂在厌恶学习或提取过程中产生的不同影响取决于糖分熟悉程度的不同
María-Isabel Miranda,Yulisa Ataucusi,Gabriela Vera-Rivera
María-Isabel Miranda
Sugar provides energy and activates several processing pathways, including the reward and memory systems, both of which are essential for feeding behavior and modulating the amount and frequency of consumption. Accordingly, the conditioned ...
Training in the Categorization of Aerial and Terrestrial Scenes Differentially Impacts Scene-Selective and Nonscene-Selective Regions in Occipitotemporal Cortex [0.03%]
场景分类训练对枕颞皮层的场景选择性区域和非场景选择性区域的不同影响
Joseph Borders,Birken Noesen,Bethany Dennis et al.
Joseph Borders et al.
Humans are extremely adept at categorizing complex visual environments, an ability supported by a network of scene-selective cortical areas in occipitotemporal cortex (OTC), primarily parahippocampal- and occipital-place area (PPA, OPA, res...
Superficial Ventral Premotor Pathways to Primary Motor Cortex Shape the Temporal Coordination of Precision Grasping [0.03%]
浅层腹侧 premotor 通路塑造初级运动皮质对精细抓握的时空协调作用
Andrea Casarotto,Elisa Dolfini,Marta Russo et al.
Andrea Casarotto et al.
Goal-directed actions, such as picking up, manipulating, or using objects, are so ubiquitous that impairments in these skills can severely impact quality of life. Reaching-grasping behaviors are driven by a frontoparietal network, with the ...
Quantifying the Influence of Lexical Surprisal on Acoustic Speech Encoding While Controlling for Within-Speaker Variability [0.03%]
控制说话人内部变异下量化词汇惊讶度对声学语音编码的影响
Shyanthony R Synigal,Michael P Broderick,Edmund C Lalor
Shyanthony R Synigal
There is substantial support for the idea that the listening brain makes predictions about upcoming speech and that these predictions are integrated with sensory input to influence perception. For example, the early auditory encoding of wor...