Caitlin Mace,Fionn OSullivan,Scott R Wilson
Caitlin Mace
Engrams are a hypothetical construct in neuroscience used to explain memory phenomena. The search for engrams has been energised by the advent of certain reductionist methods that intervene at lower levels of organisation. We defend methodo...
Domperidone Modulates Hippocampal D2 Expression, Facilitates Extinction, and Attenuates Morphine-Induced Conditioned Place Preference in Rats [0.03%]
多潘立酮可调节海马D2表达、促进消退并减轻吗啡所致条件位置偏爱反应
Amineh Sadat Zahiri-Pour,Farkhondeh Razzaghi-Firozjaei,Amir Ghaderi et al.
Amineh Sadat Zahiri-Pour et al.
Peripheral dopamine D2 receptors (D2R) have been implicated in modulating reward-related behaviors; however, their role in morphine-induced conditioned place preference (CPP) remains unclear. This study evaluated whether peripheral selectiv...
Neural Timeline of Contextual Guidance in Naturalistic Visual Search Across Task Difficulty Levels [0.03%]
基于自然场景的视觉搜索任务难度水平的神经时间线
Tiasha Saha Roy,Arpita Saha Chowdhury,Sucheta Chakravarty et al.
Tiasha Saha Roy et al.
Visual search is extremely critical in the real world and is modulated by contextual guidance. Extensive research highlights the role of contextual manipulation in enhancing visual search performance. However, the neural timeline underlying...
The Effect of Caffeine Consumption and Acute Withdrawal on Resting-State fMRI Brain Connectivity, Mood and Cognition [0.03%]
咖啡因摄入及急性戒断对静息态fMRI脑连接、情绪和认知的影响
Tatum Sevenoaks,Fiona Lancelotte,Nicholas Souter et al.
Tatum Sevenoaks et al.
Caffeine is the most widely consumed psychoactive substance, yet few studies have investigated how habitual and acute consumption and withdrawal impacts resting-state brain connectivity. Notably, prior research lacks adequate control for de...
Within-Category Mismatch Responses to Parametrically Varying Speech Sounds [0.03%]
参数化变化的语音刺激的范畴内Mismatch反应
Chao Han,Arild Hestvik,William Idsardi
Chao Han
Mismatch negativity arises from the construction of a memory trace encoding regularities extracted from auditory stimuli in an oddball paradigm. A previous study argued that when phonetic standards are varied within the limits of a phoneme ...
Jiahui Chen
Jiahui Chen
A recent work by Dewa et al. elucidates that astrocytes recruited during fear recall stabilize memory traces across extended timescales through noradrenergic signaling pathways, operating through mechanisms distinct from neuronal engrams. T...
Modulation of Amyloid and Tau Pathology by Empagliflozin in a High-Fat Diet and Streptozotocin-Induced Type 2 Diabetes-Associated Alzheimer's Model [0.03%]
恩格列净调节高脂饮食和链脲佐菌素诱导的2型糖尿病相关阿尔茨海默病小鼠模型中的淀粉样蛋白和tau病理学
Ayse Nur Hazar-Yavuz,Busra Ertas,Rumeysa Keles Kaya et al.
Ayse Nur Hazar-Yavuz et al.
Type 2 diabetes mellitus (T2DM) contributes notably to the development and progression of Alzheimer's disease (AD) through overlapping pathological mechanisms such as insulin resistance, amyloid-β (Aβ) accumulation and tau hyperphosphoryl...
Resting-State Activity and Connectivity of Dopaminergic Key Areas and Outcome After a Severe Stroke [0.03%]
多巴胺能关键区域的静息态活动和连接与严重卒中后的预后关系研究
Hanna Braaß,Liv Asmussen,Winifried Backhaus et al.
Hanna Braaß et al.
Brain reserve capacity has recently gained an increasing interest in stroke recovery research to provide a deeper understanding of outcome variability. For instance, global and focal parameters of brain health, such as white matter hyperint...
Prelimbic Cortex Activity Predicts Anxiety-Like Behavior in the Elevated Plus Maze [0.03%]
预肢皮层活性预测受刺激高架十字迷宫中的焦虑行为
Marina A Smoak,Karla J Galvan,Daniel E Calvo et al.
Marina A Smoak et al.
The medial prefrontal cortex plays a critical role in emotional regulation, and its dysregulation is linked to anxiety disorders. In particular, the prelimbic cortex of the medial prefrontal cortex is thought to modulate anxiety-related beh...