Dexmedetomidine alleviates hippocampal neuronal loss and cognitive decline in rats undergoing open surgery under sevoflurane anaesthesia by suppressing CCAAT/enhancer-binding protein beta [0.03%]
右美托咪定通过抑制CCAAT/增强子结合蛋白β缓解异氟醚麻醉大鼠开颅手术后的海马神经元丢失和认知功能障碍
Shanshan Fu,Xianghai Zhao,Yingna Li et al.
Shanshan Fu et al.
Dexmedetomidine (Dex) may exert neuroprotective effects by attenuating inflammatory responses. However, whether Dex specifically improves postoperative cognitive dysfunction (POCD) by inhibiting microglial inflammation through what pathway ...
Differential patterns of basal and naloxone-evoked dopamine efflux in the rat dorsal and ventral striatum following prolonged-intermittent exposure to morphine [0.03%]
长期间歇性暴露于吗啡后，大鼠背侧和腹侧纹状体中基线和纳洛酮诱发的多巴胺释放模式的差异
Soyon Ahn,Haiyan Zou,Jeremy K Seamans et al.
Soyon Ahn et al.
Hypodopaminergia in the ventral striatum is a putative neurobiological correlate of withdrawal in opioid-dependent individuals. This perspective stands in contrast to brain imaging studies with chronic opioid users showing that naloxone-enh...
Validity and reliability of self-reported and neural measures of listening effort [0.03%]
聆听努力的自我报告和神经测量的有效性和可靠性
Yousef Mohammadi,Jan Østergaard,Carina Graversen et al.
Yousef Mohammadi et al.
Listening effort can be defined as a measure of cognitive resources used by listeners to perform a listening task. Various methods have been proposed to measure this effort, yet their reliability remains unestablished, a crucial step before...
Obesity in pregnancy-Long-term effects on offspring hypothalamic-pituitary-adrenal axis and associations with placental cortisol metabolism: A systematic review [0.03%]
孕期肥胖对子代下丘脑-垂体-肾上腺轴的长期影响及其与胎盘皮质醇代谢的关系：系统性综述
Tabia Volqvartz,Helena Hørdum Breum Andersen,Lars Henning Pedersen et al.
Tabia Volqvartz et al.
Obesity, affecting one in three pregnant women worldwide, is not only a major obstetric risk factor. The resulting low-grade inflammation may have a long-term impact on the offspring's HPA axis through dysregulation of maternal, placental a...
Effects of D-CAG chemotherapy regimen on cognitive function in patients with acute myeloid leukaemia: A resting-state functional magnetic resonance imaging study [0.03%]
D-CAG方案对急性髓系白血病患者认知功能影响的静息态功能磁共振成像研究
Jun Hu,Ailing Su,Xianwei Liu et al.
Jun Hu et al.
Post-chemotherapy cognitive impairment, also known as 'chemobrain', is a common neurotoxic complication induced by chemotherapy, which has been reported in many cancer survivors who have undergone chemotherapy. In this study, we aimed to ex...
Eurycoma longifolia (Tongkat Ali) enhances wakefulness during active periods but facilitates sleep during resting periods in C57BL/6 mice [0.03%]
舌吻艾莉(Eurycoma longifolia)可增强小鼠活跃期的清醒状态，但有助于休息期的睡眠
Taisuke Ono,Naoya Nishino,Yusuke Iwai et al.
Taisuke Ono et al.
The effects of the Eurycoma longifolia (also known as Tongkat Ali [TA]) on sleep and wakefulness was evaluated in C57BL/6 mice. While TA has been used as an aphrodisiac in males, it exhibits various pharmacological effects. The most notable...
Theta oscillatory power decreases in humans are associated with spatial learning in a virtual water maze task [0.03%]
theta振荡功率与虚拟水域迷宫任务中的空间学习相关性研究
Conor Thornberry,Michelle Caffrey,Sean Commins
Conor Thornberry
Theta oscillations (4-8 Hz) in humans play a role in navigation processes, including spatial encoding, retrieval and sensorimotor integration. Increased theta power at frontal and parietal midline regions is known to contribute to successfu...
Inhibition of striatal dopamine release by the L-type calcium channel inhibitor isradipine co-varies with risk factors for Parkinson's [0.03%]
L型钙通道抑制剂异搏定对纹状体多巴胺释放的抑制作用与帕金森病的风险因素呈协同变异关系
Katherine R Brimblecombe,Natalie Connor-Robson,Carole J R Bataille et al.
Katherine R Brimblecombe et al.
Ca2+ entry into nigrostriatal dopamine (DA) neurons and axons via L-type voltage-gated Ca2+ channels (LTCCs) contributes, respectively, to pacemaker activity and DA release and has long been thought to contribute to vulnerability to degener...
Tutku Öztel,Fuat Balcı
Tutku Öztel
Metacognitive processing constitutes one of the contemporary target domains in consciousness research. Error monitoring (the ability to correctly report one's own errors without feedback) is considered one of the functional outcomes of meta...