Beyond nylon 6: polyamides via ring opening polymerization of designer lactam monomers for biomedical applications [0.03%]
超越尼龙6：用于生物医学应用的新型氨基酸单体开环聚合制备聚酰胺
Maria Varghese,Mark W Grinstaff
Maria Varghese
Ring opening polymerization (ROP) of lactams is a highly efficient and versatile method to synthesize polyamides. Within the last ten years, significant advances in polymerization methodology and monomer diversity are ushering in a new era ...
Biodistribution, degradability and clearance of 2D materials for their biomedical applications [0.03%]
二维材料的生物分布、降解和清除及其生物医学应用
Taojian Fan,Li Yan,Shiliang He et al.
Taojian Fan et al.
Two-dimensional (2D) materials have evolved to be a class of rapidly advancing chemical entities in the biomedical field. Nevertheless, potential side effects and safety concerns severely limit their clinical translation. After administrati...
Light olefin synthesis from a diversity of renewable and fossil feedstocks: state-of the-art and outlook [0.03%]
来自各种可再生和化石原料的轻烯烃合成：现状与展望
Sergei A Chernyak,Massimo Corda,Jean-Pierre Dath et al.
Sergei A Chernyak et al.
Light olefins are important feedstocks and platform molecules for the chemical industry. Their synthesis has been a research priority in both academia and industry. There are many different approaches to the synthesis of these compounds, wh...
PROTAC degraders as chemical probes for studying target biology and target validation [0.03%]
基于靶点的新型分子胶和降解剂化学探针的研究及应用
Václav Němec,Martin P Schwalm,Susanne Müller et al.
Václav Němec et al.
Small molecule degraders such as PROTACs (PROteolysis TArgeting Chimeras) have emerged as new promising pharmacological modalities and the first PROTAC drug candidates are now studied clinically. The catalytic properties of PROTACs, acting ...
Correction: Metal-organic framework (MOF)-, covalent-organic framework (COF)-, and porous-organic polymers (POP)-catalyzed selective C-H bond activation and functionalization reactions [0.03%]
关于金属有机框架（MOF）-、共价有机框架（COF）-和多孔有机聚合物（POP）-催化选择性C-H键活化及功能化反应的更正公告
Saba Daliran,Ali Reza Oveisi,Yong Peng et al.
Saba Daliran et al.
Correction for 'Metal-organic framework (MOF)-, covalent-organic framework (COF)-, and porous-organic polymers (POP)-catalyzed selective C-H bond activation and functionalization reactions' by Saba Daliran et al., Chem. Soc. Rev., 2022, htt...
Published Erratum
Chemical Society reviews. 2022 Sep 20;51(18):8140. DOI:10.1039/d2cs90071h 2022
New opportunities for immunomodulation of the tumour microenvironment using chemical tools [0.03%]
利用化学工具调控肿瘤微环境免疫的新机遇
Jing-Yun Su,Wen-Hao Li,Yan-Mei Li
Jing-Yun Su
Immunotherapy is recognised as an attractive method for the treatment of cancer, and numerous treatment strategies have emerged over recent years. Investigations of the tumour microenvironment (TME) have led to the identification of many po...
Calcium carbonate: controlled synthesis, surface functionalization, and nanostructured materials [0.03%]
碳酸钙：控制合成、表面官能化与纳米结构材料
Yu-Qin Niu,Jia-Hui Liu,Cyril Aymonier et al.
Yu-Qin Niu et al.
Calcium carbonate (CaCO3) is an important inorganic mineral in biological and geological systems. Traditionally, it is widely used in plastics, papermaking, ink, building materials, textiles, cosmetics, and food. Over the last decade, there...
Discovery of small molecule ligands for the von Hippel-Lindau (VHL) E3 ligase and their use as inhibitors and PROTAC degraders [0.03%]
小分子von Hippel-Lindau(E3泛素连接酶)VHL配体的发现及其作为抑制剂和靶向蛋白降解化合物的作用研究
Claudia J Diehl,Alessio Ciulli
Claudia J Diehl
The von Hippel-Lindau (VHL) Cullin RING E3 ligase is an essential enzyme in the ubiquitin-proteasome system that recruits substrates such as the hypoxia inducible factor for ubiquitination and subsequent proteasomal degradation. The ubiquit...
Platinum nanoplatforms: classic catalysts claiming a prominent role in cancer therapy [0.03%]
铂基纳米药物载体平台：传统催化剂在癌症治疗中的新角色
Jose I Garcia-Peiro,Javier Bonet-Aleta,Jesus Santamaria et al.
Jose I Garcia-Peiro et al.
Platinum nanoparticles (Pt NPs) have a well-established role as a classic heterogeneous catalyst. Also, Pt has traditionally been employed as a component of organometallic drug formulations for chemotherapy. However, a new role in cancer th...
Zoe Ashbridge,Stephen D P Fielden,David A Leigh et al.
Zoe Ashbridge et al.
Entangling strands in a well-ordered manner can produce useful effects, from shoelaces and fishing nets to brown paper packages tied up with strings. At the nanoscale, non-crystalline polymer chains of sufficient length and flexibility rand...