Mathijs J Pals,Alexander Lindberg,Willem A Velema
Mathijs J Pals
Antibacterial resistance is a severe threat to modern medicine and human health. To stay ahead of constantly-evolving bacteria we need to expand our arsenal of effective antibiotics. As such, antisense therapy is an attractive approach. The...
Progress and challenges in structural, in situ and operando characterization of single-atom catalysts by X-ray based synchrotron radiation techniques [0.03%]
基于同步辐射X射线技术的单原子催化剂结构原位和Operando表征进展与挑战
Yuhang Liu,Xiaozhi Su,Jie Ding et al.
Yuhang Liu et al.
Single-atom catalysts (SACs) represent the ultimate size limit of nanoscale catalysts, combining the advantages of homogeneous and heterogeneous catalysts. SACs have isolated single-atom active sites that exhibit high atomic utilization eff...
Nanomaterial-based regulation of redox metabolism for enhancing cancer therapy [0.03%]
基于纳米材料的红ox代谢调控增强癌症治疗研究进展
Xiaodan Jia,Yue Wang,Yue Qiao et al.
Xiaodan Jia et al.
Altered redox metabolism is one of the hallmarks of tumor cells, which not only contributes to tumor proliferation, metastasis, and immune evasion, but also has great relevance to therapeutic resistance. Therefore, regulation of redox metab...
Chamila Gunathilake,Ibrahim Soliman,Dhruba Panthi et al.
Chamila Gunathilake et al.
The transformation from combustion-based to renewable energy technologies is of paramount importance due to the rapid depletion of fossil fuels and the dramatic increase in atmospheric CO2 levels resulting from growing global energy demands...
Harnessing luciferase chemistry in regulated cell death modalities and autophagy: overview and perspectives [0.03%]
生物化学发光技术在细胞凋亡和自噬中的应用及展望
Saman Hosseinkhani,Mojdeh Amandadi,Parisa Ghanavatian et al.
Saman Hosseinkhani et al.
Regulated cell death is a fate of cells in (patho)physiological conditions during which extrinsic or intrinsic signals or redox equilibrium pathways following infection, cellular stress or injury are coupled to cell death modalities like ap...
Molecular recognition of peptides and proteins by cucurbit[ n]urils: systems and applications [0.03%]
瓜[ n ]脲对肽和蛋白质的分子识别:体系及应用
Lilyanna Armstrong,Sarah L Chang,Nia Clements et al.
Lilyanna Armstrong et al.
The development of methodology for attaching ligand binding sites to proteins of interest has accelerated biomedical science. Such protein tags have widespread applications as well as properties that significantly limit their utility. This ...
Denan Kong,Chunli Zhu,Chunyu Zhao et al.
Denan Kong et al.
Two-dimensional (2D) semiconductors have attracted considerable attention for their potential in extending Moore's law and advancing next-generation electronic devices. Notably, the discovery and development of 2D ferromagnetic semiconducto...
Exploring porous structures without crystals: advancements with pair distribution function in metal- and covalent organic frameworks [0.03%]
非晶多孔材料的结构研究:配位分布函数在金属有机框架和共价有机框架中的应用进展
Ignacio Romero-Muñiz,Edward Loukopoulos,Ying Xiong et al.
Ignacio Romero-Muñiz et al.
The pair distribution function (PDF) is a versatile characterisation tool in materials science, capable of retrieving atom-atom distances on a continuous scale (from a few angstroms to nanometres), without being restricted to crystalline sa...
Qiong Wu,Wei Xu,Jinhua Shang et al.
Qiong Wu et al.
Autocatalysis, a self-sustained replication process where at least one of the products functions as a catalyst, plays a pivotal role in life's evolution, from genome duplication to the emergence of autocatalytic subnetworks in cell division...
Mechanism and stereoselectivity in metal and enzyme catalyzed carbene insertion into X-H and C(sp2)-H bonds [0.03%]
金属和酶催化卡宾插入X-H和C(*sp2* )-H键中的机制及立体选择性研究
Reena Balhara,Ritwika Chatterjee,Garima Jindal
Reena Balhara
Constructing highly proficient C-X (X = O, N, S, etc.) and C-C bonds by leveraging TMs (transition metals) (Fe, Cu, Pd, Rh, Au, etc.) and enzymes to catalyze carbene insertion into X-H/C(sp2)-H is a highly versatile strategy. This is primar...