Suitability of the pre-nociceptive chicken embryo as a model for investigating Sporothrix spp. infection and inflammatory response [0.03%]
鸡胚胎作为研究Sporothrix感染和炎症反应模型的适用性
Júlio Marcos Ribeiro Risso,Mariana Almeida Ferreira,Lara Reis Gomes et al.
Júlio Marcos Ribeiro Risso et al.
The use of alternative in vivo models, such as chicken embryos (CE), for studying Sporothrix spp. infection aligns with sustainable and ethical research practices but remains poorly explored. This study evaluated the suitability of the pre-...
Diagnostic performance of IgG against multiplex Aspergillus antigens (mx4) for identifying chronic pulmonary aspergillosis [0.03%]
多重曲霉菌抗原(mxA4)IgG抗体诊断慢性肺曲霉病的准确性研究
Inderpaul Singh Sehgal,Ritesh Agarwa,Valliappan Muthu et al.
Inderpaul Singh Sehgal et al.
Serum A. fumigatus-IgG is the cornerstone serological test for diagnosing chronic pulmonary aspergillosis (CPA), but its sensitivity is imperfect. A multiplex Aspergillus antigen preparation (mx4) incorporating extracts of A. fumigatus, A. ...
The clinical utility of bronchoalveolar lavage galactomannan result stewardship within a tertiary medical system [0.03%]
三级医疗系统内支气管肺泡灌洗半乳甘露聚糖结果管理的临床应用价值
Anna Apostolopoulou,Sarah P Hammond,Sarah E Turbett et al.
Anna Apostolopoulou et al.
Our Transplant Infectious Disease (TID) program implemented monitoring of all elevated bronchoalveolar lavage (BAL) galactomannan (GM) results as a quality improvement (QI) project. Twenty-four hours after a positive result, a standardized ...
Cross-reactivity of Cryptococcal Antigen Lateral Flow Assay with Basidiomycetous Yeasts [0.03%]
担子菌酵母与裂隙流动测定的隐球菌抗原交叉反应性
Sarah E Kidd,Catriona L Halliday
Sarah E Kidd
The cryptococcal antigen lateral flow assay (CrAg LFA) is a widely available point of care test for the diagnosis of cryptococcal meningitis. Although there have been some reports of cross-reactivity with Trichosporon species, the extent of...
Cryptococcus gattii complex infections in southern Brazil: epidemiology, clinical features, management and outcomes from a 33-year cohort [0.03%]
巴西南里奥格兰德南部地区的新生隐球菌复合群感染：33年队列的流行病学、临床特征、治疗和转归
Bruno Hassunuma Carneiro,Regielly Caroline Raimundo Cognialli,Giovanni Luis Breda et al.
Bruno Hassunuma Carneiro et al.
Cryptococcus gattii complex has emerged as an important cause of invasive fungal disease in both immunocompetent and immunocompromised hosts, yet robust clinical and epidemiological data remain limited, particularly in Latin America. An obs...
HAC1 contributes to stress adaptation and virulence in the emerging fungal pathogen Candida auris [0.03%]
酿酒酵母菌属新兴病原真菌耳蜗毛霉菌的适应性和致病性因素HAC1的研究
Sayoko Oiki,Masahiro Abe,Ai Hirasawa et al.
Sayoko Oiki et al.
Candida auris (Candidozyma auris) is an emerging multidrug-resistant fungal pathogen that poses a significant global health threat. However, the molecular mechanisms underlying its virulence remain incompletely understood. In this study, we...
Multicenter Study Reveals Alarming Terbinafine Resistance in Trichophyton indotineae Isolates from Iran [0.03%]
一项多中心研究揭示了伊朗分离出的皮炎芽生菌特比萘芬耐药性问题
Shima Aboutalebian,Zahra Jahanshiri,Mahboobeh Kharazi et al.
Shima Aboutalebian et al.
Trichophyton indotineae has recently emerged as a major etiological agent of treatment-resistant dermatophytosis, particularly in India and Iran. Resistance to terbinafine is predominantly associated with point mutations in the squalene epo...
Human-to-animal transmission cases of the anthropophilic dermatophyte species Trichophyton tonsurans in France, 2021-2025 [0.03%]
法国2021-2025年新型致人类动物皮真菌物种顶芽毛廯菌的人畜共患病案例
Arnaud Jabet,Anne-Cécile Normand,Nicolas Soetart et al.
Arnaud Jabet et al.
Veterinary infections caused by anthropophilic dermatophytes are extremely rare and, until now, have mainly involved Trichophyton rubrum. The present investigation documents 22 cases of positive culture for the anthropophilic dermatophyte s...
Copper-only Superoxide dismutase 6 contributes to reactive oxygen species regulation, genotoxic stress tolerance and virulence in Candida albicans [0.03%]
单铜超氧化物歧化酶6参与调节铜绿色霉菌中的活性氧、致畸应力忍耐和毒力
Zhiwei Liu,Mengxue Li,Jiule Wang et al.
Zhiwei Liu et al.
Superoxide dismutase (SOD) is a major antioxidant enzyme that protects cells against reactive oxygen species (ROS)-mediated oxidative stress. The identification of a fungal-specific copper-only SOD family in Candida albicans (C. albicans) h...
Effect of postbiotics on biofilm formation and gene expression in Candida spp. isolates from patients with recurrent vulvovaginal candidiasis [0.03%]
后生元对复发性外阴阴道念珠菌病患者念珠菌生物膜形成和基因表达的影响
Jeiser Marcelo Consuegra-Asprilla,Mariana González-Idarraga,Santiago Montoya-Carrascal et al.
Jeiser Marcelo Consuegra-Asprilla et al.
First-line treatment for vulvovaginal candidiasis (VVC) has reduced efficacy in patients with recurrent VVC (RVVC), prompting the search for therapeutic alternatives such as probiotics. Recently, postbiotics (cellular components and metabol...