The Effect and Molecular Mechanism of N-Acetylglucosamine transferase-V in the Pathogenesis of Cancers [0.03%]
N-乙酰半乳糖胺转移酶V在癌症发生发展中的作用及其分子机制研究
Feng Zhang,Li-Fang Chen,Zhi-Yan Huang et al.
Feng Zhang et al.
N-Acetylglucosaminyltransferase V (GnT-V) is a pivotal glycosyltransferase catalyzing the formation of β1-6 branched N-glycans, a structural modification intimately linked to cancer malignancy. While elevated GnT-V expression correlates wi...
Glyco you should know [0.03%]
你应该了解的糖类知识
Mateu Montserrat-Canals
Mateu Montserrat-Canals
Glyco you should know [0.03%]
你应该了解的糖类知识
Emily Kukan
Emily Kukan
Labeling and Detecting Human Milk Oligosaccharides through ST3Gal3 Incorporation of Azido Sialic Acid and Gel Electrophoresis [0.03%]
通过ST3Gal3介导的叠氮神经氨酸掺入和凝胶电泳对人类乳寡糖进行标记与检测
Zhengliang L Wu,Todd A Nauman,Michael J Bowman et al.
Zhengliang L Wu et al.
Human milk oligosaccharides (HMOs) are complex sugars present in human milk. These sugars possess prebiotic, immunomodulatory, and antagonistic properties towards pathogens and therefore are important for the health and well-being of newbor...
Replication of 10 novel loci involved in human plasma protein N-glycosylation using MALDI-MS and UHPLC-FD data [0.03%]
采用基质辅助激光解析电离飞行时间质谱(MALDI-TOF MS)和超高效液相色谱示差折光检测(UHPLC-FD)技术验证10个参与人类血浆蛋白N-聚糖修饰的遗传多态性位点
Anna Timoshchuk,Annemieke Naber,Roderick Slieker et al.
Anna Timoshchuk et al.
N-glycans are essential components of glycoproteins, influencing their properties and functions. While biochemical pathways of glycosylation are well-characterized, their genetic regulation remains poorly understood. This study utilizes mat...
Development of a sensitive and specific method to measure heparanase activity in complex biological matrices [0.03%]
一种在复杂生物基质中测定他莫司汀活性的敏感和特异方法的建立
Zhangjie Wang,Robert Richter,Guowei Su et al.
Zhangjie Wang et al.
Heparanase-1 (HPSE) is the only mammalian endo-β-D-glucuronidase that cleaves heparan sulfate (HS) polysaccharides on cell surfaces and in extracellular matrices. HPSE contributes to diverse pathological conditions, particularly in the pro...
Best Practices in O-GlcNAcylation: A Survey-Based Consensus Among Researchers [0.03%]
O-连接-N-乙酰葡萄糖胺化研究中的最佳实践——基于调查的专家共识
Stephanie Olivier-Van Stichelen,Sarai Luna,Chad Slawson
Stephanie Olivier-Van Stichelen
O-GlcNAcylation is a dynamic and reversible post-translational modification contributing to various cellular processes and diseases. Despite its growing relevance, standardized methodologies and reproducibility remain challenges in the fiel...
Cytosolic mannosyltransferases involved in the endoplasmic reticulum N-glycosylation pathway exhibit bacterial ancestry [0.03%]
内质网N-糖基化途径中的细胞质甘露糖转移酶具有细菌起源
Si Xu,Shuai Chen,Yu-He Gu et al.
Si Xu et al.
Sugar Storm: O-GlcNAc signaling amid the clouds of cancer complexity [0.03%]
糖风暴：癌症复杂性云雾中的O-GlcNAc信号转导
Nusaiba N Ahmed,Riley G Young,Jessica Merzy et al.
Nusaiba N Ahmed et al.
Cancer is a systemic disease driven not only by cell-intrinsic alterations, but also by system-wide factors that regulate its initiation and progression. Among the key regulators of these processes are nutrient-sensing pathways, which coord...