Esaú Nefthaly Torres Cisneros,Ernesto Pacheco Pittaluga
Esaú Nefthaly Torres Cisneros
A child with recurrent respiratory infections and situs inversus: Kartagener's syndrome [0.03%]
反复呼吸道感染和内脏转位的儿童患者：卡塔格内综合征
Shankar Dey,Dipanjan Chowdhury,Subhrajit Naskar et al.
Shankar Dey et al.
Baroreceptor Sensitivity as an Independent Predictor for Functional Outcomes in Acute Ischemic Stroke [0.03%]
急性缺血性卒中患者预后的独立预测因素——颈动脉窦压力感受器敏感度的研究
Cheng-Chang Yen,Hsin-Hung Chen,Po-Ming Chen et al.
Cheng-Chang Yen et al.
Background: Post-stroke autonomic dysfunction is a critical determinant of long-term prognosis. Reduced baroreceptor sensitivity (BRS), a marker of this dysfunction, has been linked to adverse outcomes, but its independen...
Intravitreal pegfilgrastim for indirect traumatic optic neuropathy: a first-in-human phase 1/2a study [0.03%]
玻璃体内注射培非格司亭治疗间接性视神经创伤病变：一项针对人类的I/IIa期临床试验
Chin-Te Huang,Yao-Tseng Wen,Pei-Kang Liu et al.
Chin-Te Huang et al.
Background: Indirect traumatic optic neuropathy (TON) is associated with severe vision loss and no proven treatment. Aim: To evaluate t...
PCSK9 contributes to diabetes-associated chronic kidney injury beyond LDL cholesterol regulation: genetic and observational evidence [0.03%]
PCSK9通过调控低密度脂蛋白胆固醇以外的途径贡献于糖尿病相关慢性肾脏病：基因和观察证据
Jingjing Quan,Si Li,Juan Peng et al.
Jingjing Quan et al.
Aims: This study integrates Mendelian randomization (MR) and observational data to investigate the causal roles of PCSK9 and LDL-C in chronic kidney injury (CKI) of various etiologies, with a focus on diabetes-associated ...
Hepatitis at Home: Ambulatory management of severe immune checkpoint inhibitor related hepatitis [0.03%]
免疫检查点抑制剂相关重度肝炎的门诊管理
Tim Cooksley,Jamie Mj Weaver,Safwaan Adam et al.
Tim Cooksley et al.
Background: Liver toxicity is common in patients treated with immune checkpoint inhibitor (ICI) therapy. Most guidelines advocate for the admission of patients with grade 3/4 ICI mediated hepatitis. Ambulatory emergency c...
A Novel Phenotype of GCK c.781G>A Variant Causing Neonatal Refractory Hyperinsulinaemic Hypoglycaemia [0.03%]
GCK c.781G>A变异导致新生儿难治性低血糖的新表型
Jianfeng Lin,Yiqun He
Jianfeng Lin
Glucokinase (GCK) mutations are well-known causes of maturity-onset diabetes of the young type 2 (MODY2) and hyperinsulinaemic hypoglycaemia type 3 (HH3). The GCK c.781G>A (p.Gly261Arg) variant has been exclusively reported in MODY2. We des...
The 'Madura Hand' [0.03%]
"玛杜拉手"现象
Stuti Chandola,Manisha Jana
Stuti Chandola
Mycetoma or maduramycosis is a chronic deforming granulomatous musculoskeletal infection caused by bacteria (Actinomycetes sp) or fungi, most notably, Madurella mycetomatis. Approximately 70% of infections involve the foot, followed by hand...
Noor Almaani,Deema Rayyan,Mariana Nuseir et al.
Noor Almaani et al.
Scar sarcoidosis is a form of cutaneous sarcoidosis characterized by granulomatous inflammation arising within pre-existing scars or sites of previous trauma. These lesions may develop years after the initial injury and can mimic foreign bo...