Hepatitis at Home: Ambulatory management of severe immune checkpoint inhibitor related hepatitis [0.03%]
免疫检查点抑制剂相关重度肝炎的门诊管理
Tim Cooksley,Jamie Mj Weaver,Safwaan Adam et al.
Tim Cooksley et al.
Background: Liver toxicity is common in patients treated with immune checkpoint inhibitor (ICI) therapy. Most guidelines advocate for the admission of patients with grade 3/4 ICI mediated hepatitis. Ambulatory emergency c...
A Novel Phenotype of GCK c.781G>A Variant Causing Neonatal Refractory Hyperinsulinaemic Hypoglycaemia [0.03%]
GCK c.781G>A变异导致新生儿难治性低血糖的新表型
Jianfeng Lin,Yiqun He
Jianfeng Lin
Glucokinase (GCK) mutations are well-known causes of maturity-onset diabetes of the young type 2 (MODY2) and hyperinsulinaemic hypoglycaemia type 3 (HH3). The GCK c.781G>A (p.Gly261Arg) variant has been exclusively reported in MODY2. We des...
The 'Madura Hand' [0.03%]
"玛杜拉手"现象
Stuti Chandola,Manisha Jana
Stuti Chandola
Mycetoma or maduramycosis is a chronic deforming granulomatous musculoskeletal infection caused by bacteria (Actinomycetes sp) or fungi, most notably, Madurella mycetomatis. Approximately 70% of infections involve the foot, followed by hand...
Noor Almaani,Deema Rayyan,Mariana Nuseir et al.
Noor Almaani et al.
Scar sarcoidosis is a form of cutaneous sarcoidosis characterized by granulomatous inflammation arising within pre-existing scars or sites of previous trauma. These lesions may develop years after the initial injury and can mimic foreign bo...
Aranya Kumar Das,Ayan Mandal,Shiv Kumar Sharma et al.
Aranya Kumar Das et al.
Schistosomiasis is a parasitic disease that causes chronic intestinal inflammation, and certain Schistosoma species are implicated in colorectal carcinoma (CRC) pathogenesis. While common in endemic areas, Schistosoma-associated CRC (SA-CRC...
Lessons from Snakes: The Translational Potential of Extreme Physiological Adaptations in Cardiovascular Medicine [0.03%]
来自蛇的启示——极端生理适应在心血管医学中的转化潜力
Yihao Zhu,Lili Zhang
Yihao Zhu
Snakes have evolved remarkable physiological regulatory mechanisms to withstand extreme challenges. From postprandial cardiac hypertrophy in pythons to gravity adaptation in arboreal species and hypoxia tolerance in high-altitude snakes, th...
Shireen Dumont,Aaron Drucker
Shireen Dumont
Shuzhong Liu,Sukai Zhang,Xiaowei Li et al.
Shuzhong Liu et al.
Padraig Hawkins,Michael O&#x;Mahony,Michael John Harrison et al.
Padraig Hawkins et al.