Gene editing and multi-omics approaches to study early embryogenesis in cattle [0.03%]
基因编辑和多组学方法研究牛早期胚胎发生
Kun Zhang
Kun Zhang
Advancements in multi-omics profiling and targeted molecular functional tools have led to significant progress in our understanding of early embryonic development in mammals. This is very relevant in the beef and dairy industries for explor...
Heterospermic semen: Implications for managing bull-to-bull variation in fertility [0.03%]
异精精液对管理公牛繁殖力个体差异的影响
Sean Fair
Sean Fair
Heterospermic (HS) bull semen involves mixing the semen from two or more sires in the same semen straw. It has the potential to protect against sub-fertile bulls which pass semen quality control checks, due to the presence of sperm from oth...
Rebecca Poole
Rebecca Poole
Historically, bacteria identified within the reproductive tract of cattle using culture-based techniques were associated with disease. Indeed, bacterial genera including Fusobacterium, Bacteroides, Prevotella, and Porphyromonas identified b...
Maria Paramio
Maria Paramio
Juvenile in vitro embryo transfer (JIVET) employs oocytes from prepubertal females to reduce generation intervals. In human, it offers potential applications for fertility preservation in young cancer patients. Ruminant animals are good mod...
When Less Really Is More: Reducing Embryo Manipulation to Lower Metabolic Stress and Improving Long Term Outcomes [0.03%]
少即是多：减少胚胎操作以降低代谢压力和改善长期结局
Paolo Rinaudo
Paolo Rinaudo
The use of assisted reproductive technologies (ARTs) to treat human infertility has increased exponentially in recent years. In addition to improved access to care for infertile patients, there is a significant increase in ART utilization i...
Embryonic HBEGF regulates FoxO1 through PI3K signaling as embryo breaches maternal epithelial barrier [0.03%]
胚胎在突破母体上皮屏障时通过PI3K信号调节FoxO1的胚胎HBEGF
Dileyra Adiguzel,Leyla Sati,Ciler Celik-Ozenci
Dileyra Adiguzel
Purpose: The initial barrier encountered by the embryo during the pivotal phase of implantation and subsequent pregnancy maintenance is the maternal endometrial epithelial barrier. This study aims to elucidate the interac...
Towards understanding mare endometrosis - ex vivo study on the role of relaxin [0.03%]
mares子宫内膜异位症的病因及松弛素的作用机制体外研究
Magdalena Profaska,Marta Zarzycka,Klaudia Dubniewicz et al.
Magdalena Profaska et al.
Context: Mare endometrosis remains a poorly understood pathological process. Aims: Mare endometrial tissue with endometrosis was used t...
Guanidinoacetic acid supplementation negatively impacts bovine cumulus oocyte complexes during in-vitro maturation [0.03%]
瓜氨酸补充剂会损害体外成熟的牛卵母细胞复合体的功能
Alexandria Snider,Martim Kaps,Lea Rempel et al.
Alexandria Snider et al.
Methylation is an important part of oocyte maturation and early embryonic development. Altered methylation status leads to poor oocyte quality and altered embryonic development. One specific metabolite, guanidinoacetic acid (GAA), sequester...
Eckhard Wolf
Eckhard Wolf
The translation of novel discoveries in biomedical research into clinical applications is a lengthy and resource-intensive process, with variable success. Predictive model organisms for nonclinical research are a key asset in this process. ...
Prenatal development of the intramural vascular system of the uterine tube in the European shorthair cat [0.03%]
欧洲短毛猫输卵管壁血管系统的胚胎发育
Ewelina Prozorowska-Basinska,Hanna Jackowiak
Ewelina Prozorowska-Basinska
Context: Early vascular development during the prenatal period is essential for the proper formation of all organs, including the reproductive system. Aim...