Genistein mitigates ovarian dysfunction in a PCOS mouse model by regulating steroidogenesis, apoptosis, and PARP-1 signaling [0.03%]
染料木素通过调节类固醇生成、凋亡和PARP-1信号通路缓解PCOS小鼠模型的卵巢功能障碍
Jin Wang,Fenglan Lu,Zhuoqian Guo et al.
Jin Wang et al.
Context: Polycystic ovary syndrome (PCOS) is a common endocrine disorder marked by hormonal and clinical imbalances. Genistein (GEN), a soy isoflavone with antioxidant properties, has shown promise in PCOS treatment, alth...
Platelet-rich plasma strategy against freezing damage in ram spermatozoa: its effect on miRNA, ion channels, growth factors, lipids and oxidative stress [0.03%]
富含血小板血浆策略对抗公羊精子冷冻损伤：其对miRNA、离子通道、生长因子、脂质和氧化应激的影响
İbrahim Halil Güngör,Gaffari Türk,Aslıhan Çakır Cihangiroğlu et al.
İbrahim Halil Güngör et al.
Context: Platelet-rich plasma (PRP) is a plasma component containing high concentrations of platelets, growth factors, antioxidants and proliferative properties. ...
Sperm interaction in the hyperandrogenized female reproductive tract might contribute to female infertility: a hypothesis [0.03%]
高雄激素化女性生殖道中精子相互作用可能会影响女性不孕：一种假说
Annie Lalrawngbawli,Nitu Kaur,Guruswami Gurusubramanian et al.
Annie Lalrawngbawli et al.
It is well known that hyperandrogenism (HA) in females is associated with oligo-ovulation or anovulation, leading to subfertility. The abnormality in ovulation is due to ovarian dysfunction. However, it remains unclear whether ovarian dysfu...
Relationship between plasma sex steroids and cell proliferation-related gene expression in the uterus during dioestrus in nonpregnant bitches [0.03%]
犬黄体期子宫细胞增殖相关基因表达与血浆性激素水平的关系研究
Vanessa da Silva Alves Gossler,Sarah Gomes Nunes,Francislaine Anelize Garcia Santos et al.
Vanessa da Silva Alves Gossler et al.
Context: Reproductive processes in mammals involve complex interactions between sex steroids and growth factor systems. Understanding these interactions in the uterus during different stages of the reproductive cycle is e...
The impact of obesogenic disturbances on in vitro fertilization outcomes in a Mexican population [0.03%]
肥胖对墨西哥人口体外受精结局的影响研究
Yúvika Reyes-Albarracín,Leonardo M Porchia,M Elba Gonzalez-Mejia et al.
Yúvika Reyes-Albarracín et al.
Context: Overweight and obese patients tend to have more difficulty getting pregnant through in vitro fertilization (IVF), but it is still unclear whether this effect varies by ethnicity and age. ...
Dong-Hyeok Kwon,Jeong-Hwa Lee,Hee Kyoung Kim et al.
Dong-Hyeok Kwon et al.
Context: Endometrial organoids (EOs) have gained attention as a promising in vitro model for investigating uterine physiology, reproductive disorders, and embryo-maternal interactions, providing an alternative to in vivo ...
Optimizing gene expression analysis under hypoxia: identification and validation of novel reference genes in steroidogenic tissues and cell lines [0.03%]
缺氧条件下优化基因表达分析：类固醇生成组织和细胞系中新型参考基因的鉴定与验证
Olivia Eilers Smith,Luiz Antonio Berto Gomes,Mariusz Pawel Kowalewski
Olivia Eilers Smith
Context: Signaling pathways that regulate steroidogenesis are known to be modulated by varying oxygen levels. Thus, appropriate internal controls unaffected by hypoxia are essential for accurate assessement of oxygen-depe...
Comparative reproductive biology, advances in reproductive health, and cultivating inclusion in the scientific community: highlights from the 2024 Annual Meeting of the Society for Reproductive Biology [0.03%]
生殖生物学的比较研究、生殖健康领域的进展以及在科学界培养包容性：2024年生殖生物学会年会亮点
Hon Y Chan,Lauren R Alesi,Doan T Dinh et al.
Hon Y Chan et al.
In 2024, the reproductive biology research community in Australia and New Zealand reunited in Adelaide for the Society for Reproductive Biology (SRB) Annual Meeting. The conference showcased major advances made in key areas of reproductive ...
Data-driven biomarker discovery and risk profiling for polycystic ovary syndrome in Indian women using ensemble learning [0.03%]
基于印度女性的多囊卵巢综合症的数据驱动生物标志物发现和风险分析
Pulkit Verma,Rekha Agarwal,Lokesh Kumar Sharma et al.
Pulkit Verma et al.
Context: Despite diagnostic advancements in India, the scarcity of Indian polycystic ovary syndrome (PCOS) data and varied diagnostic standards contribute to delays in PCOS detection, particularly in rural areas. ...
Combined effects of the Booroola, Vacaria and Embrapa mutations on ovulation rate in a sheep flock with unique genetic background [0.03%]
博罗拉、瓦卡里亚和EMBRAPA突变对具有独特遗传背景的羊群排卵率的综合影响
Carlos Jose Hoff de Souza,Magda Vieira Benavides,Jose Carlos Ferrugem Moraes
Carlos Jose Hoff de Souza
Context: Improve lamb meat production in southern Brazil using genotype-assisted selection to enhance prolificacy. Aim: To evaluate the...