SOD1 and SOD2 gene variants are significantly correlated with male infertility in a North Indian population, suggesting a possible pleiotropic conflict [0.03%]
北印度人群中的SOD1和SOD2基因变异与男性不育显著相关,暗示了可能的多效性冲突
Sonali Bhan,Manisha Bhagat,Shreya Sopori et al.
Sonali Bhan et al.
Background: Oxidative stress has a detrimental effect on sperm quality, which can lead to infertility. Antioxidant enzymes, such as superoxide dismutases (SODs) have crucial role to protect sperms from oxidative stress. V...
Investigation of endocannabinoid 2-AG and its hydrolases for regulation on sperm motility and acrosome reaction in Kunming mice [0.03%]
大麻素系统对昆明小鼠精子运动性和顶体反应的调节作用及机制研究
Xin Zhang,Wenjing Wu,Yahui Li et al.
Xin Zhang et al.
Context 2-AG (2-arachidonoyl glycerol), a key endocannabinoid, regulates sperm hyperactivation in humans via ABHD2 (alpha/beta hydrolase domain-containing protein 2)-mediated CatSper calcium channel activation. However, ABHD2's role in mice...
Is Intracytoplasmic Sperm Injection (ICSI) The Solution When There Isn't Any Problem; Exploring ICSI Vs. In vitro fertilization (IVF) Outcomes in Sibling Oocytes from Donor Sperm Assisted Reproductive Technology (ART) Cycles [0.03%]
当没有问题时,单精子卵胞浆内注射是否为解决方案?通过供精辅助生殖技术周期探讨ICSI与IVF的胚胎种植率及活产率比较研究
Ella Golbary Kinory,Yael Kalma,Shir Lavie et al.
Ella Golbary Kinory et al.
Context: Intracytoplasmic Sperm Injection (ICSI) is increasingly used in assisted reproductive technology (ART), even in cases without male factor infertility. It's true benefit in such scenarios remains uncertain. ...
Lysine succinylation: A review of its impacts on the reproductive function and related disease [0.03%]
赖氨酸琥珀酰化对生殖功能及其相关疾病的影响研究进展
Xinyuan Huang,Yupei Huang,Jingrong Lai et al.
Xinyuan Huang et al.
Lysine succinylation is a recently identified post-translational modification of proteins that has been demonstrated to play critical roles in various biological activities. In recent years, research on succinylation has progressed consider...
Comparison of the establishment of rat intrauterine adhesion models utilizing the double injury method at different periods [0.03%]
不同时间段双损伤法建立大鼠宫腔粘连模型的比较研究
Yawen Yan,Fei Wang,Mingjing Qiao et al.
Yawen Yan et al.
Context A suitable animal model of IUA is crucial for further investigating its pathological mechanisms and exploring effective therapeutic strategies.Aims This study compared the efficacy of establishing IUA animal models in non-pregnant r...
ALB, GPX5 and PTGDS as potential biomarkers for the aging processes of the dog epididymis [0.03%]
犬附睾衰老过程的潜在生物标志物ALB、GPX5和PTGDS
Aleksandra Cichowska-Likszo,Paweł Likszo,Leyland Fraser et al.
Aleksandra Cichowska-Likszo et al.
Context: Alterations in the reproductive tract related to aging processes are reflected by changes in biochemical components such as proteins. Aims: ...
Advancements in sperm selection and assessment: traditional to cutting-edge methods in assisted reproductive techniques - a narrative review [0.03%]
精子挑选和评估的进展:辅助生殖技术从传统到前沿的方法-叙述性综述
Alicja Staśczak,Weronika Losa,Sebastian Student et al.
Alicja Staśczak et al.
Infertility affects approximately 15% of couples globally, with male factors contributing to 20-70% of cases. These issues often stem from low sperm concentration, abnormal morphology, or poor motility, highlighting the critical importance ...
In vivo and in vitro effects of GnRH Antagonist treatment on steroidogenesis and folliculogenesis in the ovary of cyclic mice [0.03%]
GnRH拮抗剂对发情小鼠卵巢类固醇生成和卵泡发育的体内和体外效应
Padmasana Singh,Raj Kamal Srivastava,Amitabh Krishna
Padmasana Singh
Context: Gonadotropin-releasing hormone antagonists (GnRH-Anta) can modulate reproductive hormonal activity without inducing the initial surge in luteinizing hormone and follicle-stimulating hormone typically associated w...
Medicago sativa alleviates behavioral impairments and oxidative stress in cerebrum and cerebellum of ovariectomized mice [0.03%]
苜蓿对卵巢切除小鼠大脑和小脑行为缺陷及氧化应激的改善作用
Fatma Ghorbel Koubaa,Hajer Jdidi,Mariem Chaâbane et al.
Fatma Ghorbel Koubaa et al.
Background: Estrogen deficiency after menopause is associated with an increased oxidative stress and a cognitive impairment. Given the antioxidant properties of Medicago sativa, this study aimed to evaluate its effects on...
Efficacy of glyoxal acid-free (GAF®) as a non-toxic fixative for fish gonads, gametes and larvae: widespread implications for laboratory studies, field sampling and applied aquaculture [0.03%]
一种无毒的鱼类性腺、精子和鱼苗固定剂glyoxal acid-free(GAF):在实验室研究,野外采样及水产养殖中的广泛应用及其功效评估
Lisa Locatello,Elisa Fonsatti,Paolo Detillo et al.
Lisa Locatello et al.
Context: Traditional fixatives such as buffered formaldehyde (BF) and paraformaldehyde (PFA) are widely used but raise health concerns due to their toxicity. Their use is increasingly subject to regulatory restrictions, c...