Betulonic acid regulates oviduct epithelial cell inflammation through the TLR4, MAPK, and JAK/STAT signalling pathways [0.03%]
betulin酸通过TLR4、MAPK和JAK / STAT信号通路调节输卵管上皮细胞炎症反应
Liang Shao,Yan Yan,Nansu Wang et al.
Liang Shao et al.
Context: Infertility is a common disease among women of childbearing age and seriously endangers the reproductive health of human beings. Aims: ...
Sulfasalazine exposure during pregnancy and lactation: reproductive outcomes in male rat offspring [0.03%]
磺胺水杨酸在妊娠和哺乳期的接触对雄性大鼠后代的生殖结局的影响
Simone Forcato,Ana Beatriz de Oliveira Aquino,Lorena I Borges et al.
Simone Forcato et al.
Context: Sulfasalazine (SAS) is a drug prescribed for pregnant and breastfeeding women with chronic inflammatory bowel diseases. SAS treatment induces transitory infertility in both adult men and male rats. Although SAS c...
Melatonin improves the ability of spermatozoa to bind with oocytes in the mouse [0.03%]
褪黑素可提高小鼠精子与卵细胞的结合能力
YaNan Liu,YuSheng Zhang,ZeLin Wang et al.
YaNan Liu et al.
Context and aims: Melatonin is a powerful antioxidant regulating various biological functions, including alleviating male reproductive damage under pathological conditions. Here, we aim to analyse the effect of melatonin ...
Pentoxifylline promotes spermatogenesis via upregulation of the Nrf2-ARE signalling pathway in a mouse model of germ-cell apoptosis induced by testicular torsion-detorsion [0.03%]
培哚普利胺通过上调Nrf2-ARE信号通路促进由睾丸扭转复位诱导的生精细胞凋亡小鼠模型的精子发生
Omotosho Dhulqarnain Akanji,Golamreza Hassanzadeh,Mehrnoush Malekzadeh et al.
Omotosho Dhulqarnain Akanji et al.
Context: Testicular torsion-detorsion results in loss of germ cells and infertility. Pentoxifylline has been shown to prevent tissue damage. Aims: ...
Platelet-rich plasma and ovarian quiescence: a bovine in vitro model for regeneration of the ovary [0.03%]
富含血小板的血浆和卵巢静止：牛卵巢再生的体外模型
Anna Lange-Consiglio,Giulia Gaspari,Pietro Riccaboni et al.
Anna Lange-Consiglio et al.
Context: Ovarian quiescence can be due to hormonal deficiency usually caused by apoptosis of granulosa cells responsible for oestrogen synthesis. Aim: ...
Oviductal sperm storage in the Chinese pond turtle, Mauremys reevesii, depends on androgen-based promotion of the BCL 2 anti-apoptotic pathway [0.03%]
雄激素依赖的BCL-2抗凋亡通路决定中华草龟输卵管精子储存能力
Wei Chen,Yajie Wang,Mengmeng Gong et al.
Wei Chen et al.
Context: Sperm storage is a complex and highly coordinated process that is regulated by a variety of factors. The BCL 2 protein family plays a key role in regulating apoptosis, and determines sperm survival. ...
Corrigendum to: Decreased expression of DNA methyltransferases in the testes of patients with non-obstructive azoospermia leads to changes in global DNA methylation levels [0.03%]
DNA甲基转移酶在非梗阻性无精子症患者睾丸中表达降低导致全基因组DNA甲基化水平改变的校正说明文章
Fatma Uysal,Gokhan Akkoyunlu,Saffet Ozturk
Fatma Uysal
DNA methylation plays key roles in epigenetic regulation during mammalian spermatogenesis. DNA methyltransferases (DNMTs) function in de novo and maintenance methylation processes by adding a methyl group to the fifth carbon atom of the cyt...
Betaine ameliorates high glucose-induced oxidative stress in granulosa cells [0.03%]
甜菜碱通过改善颗粒细胞氧化应激状态缓解高糖毒性作用
Mohammad Hussein Abnosi,Mohammad Reza Tabandeh,Fatmeh Mosavi-Aroo
Mohammad Hussein Abnosi
Context: In diabetes, abnormalities of granulosa cells (GCs) and steroidogenesis are associated with hyperglycaemia-induced oxidative stress. Betaine has beneficial effect in experimental model of diabetes by reducing oxi...
Quantitative proteomic analysis of heifer serum at the peri-implantation period using two complementary methods [0.03%]
基于两种互补方法的围植入期雌性黄牛血清定量蛋白质组分析
Jimena Inés Ruiz Álvarez,Juan Manuel Teijeiro,Caroline Evans et al.
Jimena Inés Ruiz Álvarez et al.
Context: Systemic events resulting from mother-embryo relation at the peri-implantation period may result in specific changes to the protein composition of serum and thus provide a source of biomarkers for early detection...
Bioinformatics analysis and verification of hub genes in 46,XY, disorders of sexual development [0.03%]
46,XY性发育异常枢纽基因的生物信息学分析及验证
Zilong Cao,Liqiang Liu,Zhaoyun Bu et al.
Zilong Cao et al.
Context: 46,XY, disorders of sexual development (46,XY, DSD) is a congenital genetic disease whose pathogenesis is complex and clinical manifestations are diverse. The existing molecular research has often focused on sing...