Systemic adiponectin treatment reverses polycystic ovary syndrome-like features in an animal model [0.03%]
系统性脂联素治疗可逆转动物模型的多囊卵巢综合征样特征
Anusha Singh,Puran Bora,Amitabh Krishna
Anusha Singh
The present study examined the efficacy of adiponectin for regulating the reproductive, metabolic and fertility status of mice with polycystic ovary syndrome (PCOS). PCOS was induced in prepubertal (21- to 22-day-old) mice using dehydroepia...
Association of the cysteine-rich secretory protein-3 (CRISP-3) and some of its polymorphisms with the quality of cryopreserved stallion semen [0.03%]
胱抑素富丝氨酸家族成员3(CRISP-3)及其某些多态位点与冻融种马精液品质的关系研究
Alexandra Usuga,Benjamín A Rojano,Giovanni Restrepo
Alexandra Usuga
Contribution of seminal plasma proteins to semen freezability has been reported in several species, suggesting these proteins as genetic markers. The aim of this study was to evaluate the relationship between cysteine-rich secretory protein...
Insulinotropic nucleobindin-2/nesfatin-1 is dynamically expressed in the haemochorial mouse and human placenta [0.03%]
胰岛素核结合素-2/nesfatin-1在啮齿目和人类的血绒毛膜性胎盘中动态表达
Crystalyn B Legg-St Pierre,Martina Mackova,Ewa I Miskiewicz et al.
Crystalyn B Legg-St Pierre et al.
The placenta is the physiological bridge between mother and fetus and has life-sustaining functions during pregnancy, including metabolic regulation, fetal protection and hormone secretion. Nucleobindin-2 (NUCB2) is a calcium- and DNA-bindi...
Milk-fat globule epidermal growth factor 8 (MFGE8) is expressed at the embryo- and fetal-maternal interface in equine pregnancy [0.03%]
马胚胎和胎儿-母体界面表达乳脂肪球上皮生长因子8(MFGE8)蛋白
S Barua,A Macedo,D S Kolb et al.
S Barua et al.
Milk-fat globule epidermal growth factor (EGF) 8 protein (MFGE8), also known as lactadherin, promotes cell adhesion in an Arg-Gly-Asp (RGD)-dependent modus via integrins. In the present study, the expression of MFGE8 was examined in equine ...
Spermatogenic phenotype of testis-specific protein, Y-encoded, 1 (TSPY1) dosage deficiency is independent of variations in TSPY-like 1 (TSPYL1) and TSPY-like 5 (TSPYL5): a case-control study in a Han Chinese population [0.03%]
睾is特异Y染色体基因编码蛋白1(TSPY1)剂量缺乏对精子发生的影响与TSPY-like 1(TSPYL1)和TSPY-like 5(TSPYL5)变异无关:一项针对汉族人群的病例对照研究
Xiling Yang,Xiangyou Leng,Wenling Tu et al.
Xiling Yang et al.
Testis-specific protein, Y-encoded, 1 (TSPY1) is involved in the regulation of spermatogenic efficiency via highly variable copy dosage, with dosage deficiency of the multicopy gene conferring an increased risk of spermatogenic failure. TSP...
Mouse double minute homologue 2 (MDM2) downregulation by miR-661 impairs human endometrial epithelial cell adhesive capacity [0.03%]
微RNA-661通过下调双分钟同源物2基因抑制人子宫内膜上皮细胞黏附能力
Amy Winship,Amanda Ton,Michelle Van Sinderen et al.
Amy Winship et al.
Human blastocysts that fail to implant following IVF secrete elevated levels of miR-661, which is taken up by primary human endometrial epithelial cells (HEECs) and impairs their adhesive capability. MicroRNA miR-661 downregulates mouse dou...
Debra K Berg,Peter L Pfeffer
Debra K Berg
We profiled 98 mature microRNAs (miRNAs) using a stem-loop reverse transcription polymerase chain reaction assay array based on human miRNAs. We demonstrated that one, but not two, base-pair changes in the miRNA recognition sequence at the ...
Production of inbred offspring by intracytoplasmic sperm injection of oocytes from juvenile female mice [0.03%]
通过小鼠幼女卵母细胞胞浆内精子注射制备近交系后代
Jie Zhu,Wei Cui,Yan-Feng Dai
Jie Zhu
The aim of the present study was to determine whether the use of oocytes from juvenile female mice would improve the efficiency of intracytoplasmic sperm injection (ICSI). In the present study, 15 adult and 14 juvenile C57BL6/J female mice ...
Innate immune genes in persistent mating-induced endometritis in horses [0.03%]
与持久交配诱发的母马子宫内膜炎相关的固有免疫基因
Christina D Marth,Simon M Firestone,Dave Hanlon et al.
Christina D Marth et al.
Persistent mating-induced endometritis (PMIE) severely decreases fertility in horses. The aim of the present study was to evaluate differences between horses susceptible to PMIE and a control group in terms of the expression of selected imm...
Angiogenesis and oxidative stress-related gene variants in recurrent pregnancy loss [0.03%]
血管生成及氧化应激相关基因多态性与反复自然流产的关系研究
Marcela Felix Fortis,Lucas Rosa Fraga,Juliano André Boquett et al.
Marcela Felix Fortis et al.
Recurrent pregnancy loss (RPL) affects ~3-5% of couples attempting to conceive and in around 50% of cases the aetiology remains unknown. Adequate vascularisation and placental circulation are indispensable for the development of a normal pr...