Formation of the hyaluronan-serum-derived hyaluronan-associated protein complex during cumulus expansion contributes to in vitro maturation of porcine oocytes [0.03%]
透明质酸-血清衍生的透明质酸结合蛋白复合物的形成有利于体外培养的小鼠卵母细胞成熟
Masaki Yokoo,Naoko Kimura
Masaki Yokoo
Context: Serum-derived hyaluronan-associated proteins (SHAPs), which are identical to the heavy chains of the inter-α-trypsin inhibitor (ITI) family of proteins, bind to hyaluronan produced by cumulus cells, thus forming...
Impact of repeated ovulation induction and superovulation on ovarian reserve and early embryo development in obese and PCOS-like mouse models [0.03%]
反复促排卵和超数排卵对肥胖和PCOS样小鼠卵巢储备及早期胚胎发育的影响
Jyolsna Ponnaratta Kunhiraman,Reyon Dcunha,Vanishree Vasave Madhvacharya et al.
Jyolsna Ponnaratta Kunhiraman et al.
Context: Women with obesity or polycystic ovary syndrome (PCOS) often require repeated ovulation induction (OI) due to ovulatory dysfunction and infertility. However, the cumulative effects of repeated stimulation on ovar...
Dynamic of extracellular matrix remodeling and follicular morphology in cattle ovarian slices cultivated in medium supplemented with Croton argyrophyllus Kunth essential oil [0.03%]
添加Croton argyrophyllus Kunth精油培养的牛卵巢切片中细胞外基质重塑及卵泡形态动力学特征的研究
Emanoel da S Félix,Venância A N Azevedo,Felipe F da Silva et al.
Emanoel da S Félix et al.
Context: Ovarian tissue culture is commonly associated with increased follicular degeneration and extracellular matrix (ECM) changes largely owing to oxidative stress. ...
FGF2, LIF, and IGF1 supplementation during in vitro maturation or culture improves equine ICSI embryo development in an age-dependent manner [0.03%]
体外发育因子对马ICSI胚胎发育的影响年龄依赖性试验
Joanne M Smith,Patricio D Palacios,Pablo Andrés Segura Forero et al.
Joanne M Smith et al.
Context: Ovum pickup (OPU) combined with intracytoplasmic sperm injection (ICSI) has reshaped equine assisted reproduction, enabling embryo production from mares and stallions with constrained breeding opportunities; howe...
Paeonol alleviates intrauterine adhesion by suppressing endometrial stromal cell activation via AKT1, based on network pharmacology [0.03%]
基于网络药理学研究丹皮酚通过抑制AKT1信号通路减少子宫内膜基质细胞活化从而缓解宫腔粘连的作用机制研究
Weilan Liu,Wenxin Shi,Jiahua Zheng et al.
Weilan Liu et al.
Context: Intrauterine adhesion (IUA) causes secondary infertility and recurrent miscarriage, yet therapeutic options remain limited. Paeonol is widely used for gynecological diseases, but its precise role in IUA therapy i...
Integrative analysis of follicular fluid metabolites, exosomal miRNAs and granulosa cell mRNAs shows their interplay in women of advanced maternal age [0.03%]
整合卵泡液代谢物、外泌体miRNA和颗粒细胞mRNA的分析显示其在高龄妇女中的相互作用
Zhengda Li,Shikai Wang,Xianbao Mao et al.
Zhengda Li et al.
Context: Advanced maternal age (especially over 40 years) shows markedly declined fertility, although the exact mechanisms remain unclear. Exosomal microRNAs (miRNAs) within follicular fluid (FF) regulate granulosa cell (...
T Sun,F J Diaz
T Sun
Context: Yes-associated protein 1 (YAP1) plays essential roles in somatic cell proliferation and differentiation and is regulated by cell cycle proteins and mechanical cues transduced by the actin cytoskeleton. YAP1 has b...
Your field needs your data! Raising the standard of quality control and data accessibility in reproductive proteomics [0.03%]
您的领域需要您的数据！提高生殖蛋白质组学的质量控制和数据可访问性的标准
David A Skerrett-Byrne
David A Skerrett-Byrne
The field needs your data. Despite rapid progress in reproductive proteomics, a major barrier to scientific advancement remains the limited availability and transparency of proteomic datasets. Although more than 2000 sperm proteomics studie...
Synergistic effect of glutathione and metformin mitigates testicular apoptosis by ameliorating gonadotropin hormones and gene expression in streptozotocin-induced diabetic male mice [0.03%]
谷胱甘肽和二甲双胍的协同作用通过改善促性腺激素激素和基因表达来缓解链脲佐菌素诱导的糖尿病雄性小鼠睾丸凋亡效应
Razia Sardar,Fathiah Abdullah,Yuhaniza Shafinie Kamsani et al.
Razia Sardar et al.
Context: Diabetes mellitus (DM) is a metabolic disorder that impairs the body's ability to regulate blood sugar levels, leading to cellular damage and apoptosis. Metformin (Met) and glutathione (GSH) are key antioxidants ...
IL10 is a potent modulator of IL1-mediated inflammation in bovine endometrial explants [0.03%]
IL10是调节牛子宫内膜碎片中IL1介导的炎症的一个强有力的调节因子
Marie Margarete Meyerholz-Wohllebe,Anna Maria Kneidl,Simone Tamara Knoch et al.
Marie Margarete Meyerholz-Wohllebe et al.
Context: Bovine uterine inflammation impairs fertility, animal welfare and economics. Balanced regulation of interleukin-1 family proteins is crucial to resolve endometrial inflammation. ...