Lessons learned: real-world effectiveness of dupilumab in patients with eosinophilic esophagitis [0.03%]
Dupixent治疗嗜酸细胞性食管炎的现实世界有效性总结
Carl Olson,Jameel Alp,Nicha Wongjarupong et al.
Carl Olson et al.
Eosinophilic esophagitis (EoE) is a chronic inflammatory disease of the esophagus. Dupilumab, an IL-4/IL-13 inhibitor, was approved for EoE in 2022, but real-world data remain limited. We evaluated its effectiveness in a single tertiary car...
Diagnostic performance of computed tomography short-axis diameter for supraclavicular lymph node metastasis after neoadjuvant chemotherapy for esophageal squamous cell carcinoma [0.03%]
新辅助化疗后食管鳞癌上纵隔淋巴结转移的CT短径诊断价值评估
Naoki Takahashi,Akihiko Okamura,Masayoshi Terayama et al.
Naoki Takahashi et al.
Esophageal squamous cell carcinoma (ESCC) often metastasizes to supraclavicular lymph nodes (SCLNs), which are potentially curable distant metastases by SCLN dissection during esophagectomy. Prophylactic SCLN dissection should be based on a...
Esophageal function after paraoesophageal hernia repair: manometric and symptomatic outcomes [0.03%]
食管裂孔疝修补术后的食管功能：测压和症状结果
Pratik Raichurkar,Oleksandr Khoma,Fienne Cordeschi et al.
Pratik Raichurkar et al.
Symptoms of dysphagia and chest pain in large paraoesophageal hernias (POH) can mimic disorders of esophageal motility. High-resolution manometry (HRM) is the gold standard for assessing esophageal motility, however limited data exist in th...
The metabolic profile of lean patients with esophageal adenocarcinoma and Barrett's esophagus [0.03%]
瘦型食管腺癌和巴雷特食管患者的代谢特征
Tarek Sawas,Joanne T Benson,Alina Allen et al.
Tarek Sawas et al.
Central obesity is a risk factor for esophageal adenocarcinoma (EAC) independent of acid reflux. However, about a quarter of patients with Barrett's esophagus (BE) and EAC have a normal body mass index (BMI). One hypothesis is that chronic ...
Adjuvant immunotherapy in esophageal squamous cell carcinoma after radiotherapy: retrospective multicentric survival analysis [0.03%]
放疗后食管鳞癌的辅助免疫治疗：多中心回顾性生存分析
Weiwei Zeng,Jianlin Long,Benxu Tan et al.
Weiwei Zeng et al.
Background: Immunotherapy improves survival with manageable toxicity in esophageal cancer as neoadjuvant, first-line, or second-line therapy. However, its adjuvant role in esophageal squamous cell carcinoma (ESCC) remains...
Development of a novel patient-oriented tool to assess achalasia symptoms and response to treatment (I-PASS, International Patient-oriented tool for Achalasia Symptom Score) [0.03%]
一种新的以患者为中心的评估难治性食管下端痉挛症症状及治疗反应的工具(I-PASS，国际性的患者为中心的评估难治性食管下端痉挛症量表)的研发
Giovanni Zaninotto,Sheraz R Markar,Rami Sweiss et al.
Giovanni Zaninotto et al.
Achalasia treatment outcomes are often assessed using the Eckardt score, which has not been formally validated and is not designed as a patient-reported outcome (PRO) tool. To address this unmet clinical need, a group of healthcare provider...
Durability and reflux outcomes of peroral endoscopic myotomy compared to laparoscopic heller myotomy in achalasia: a meta-analysis of long-term studies [0.03%]
与 Heller 手术相比，经口肌层切开术治疗贲门失迟缓症的长期疗效和反流结局：一项 Meta 分析
Mohamed Abosheisha,Elmoatazbellah Nasr,Muhammed Kandeel et al.
Mohamed Abosheisha et al.
Background: Peroral endoscopic myotomy (POEM) has emerged as a minimally invasive alternative to laparoscopic Heller myotomy (LHM) for the treatment of achalasia. While short-term outcomes have been widely studied, eviden...
Bachviet Nguyen,Chun Fang Cheng,Fahd Jowhari
Bachviet Nguyen
Background: Lymphocytic esophagitis (LyE) is a novel rare esophageal disorder characterized by intraepithelial lymphocytic infiltration of the esophagus in a peripapillary distribution, without the involvement of granuloc...
Risk factors of postoperative complications and prognostic factors in patients undergoing esophagectomy reconstructed with colonic interposition [0.03%]
结肠间置食管切除术患者术后并发症的风险因素及预后因素分析
Naoki Takahashi,Akihiko Okamura,Masayoshi Terayama et al.
Naoki Takahashi et al.
Colonic interposition following esophageal resection remains challenging. Few studies have investigated the risk factors for postoperative complications and the prognostic factors in patients who underwent this type of surgery. We evaluated...
Long-term treatment in eosinophilic esophagitis: continue, taper, or stop? [0.03%]
长期治疗嗜酸性食管炎：继续、减量或停止？
Alberto Barchi,Edoardo Vespa,Edoardo Savarino et al.
Alberto Barchi et al.