Public acceptance and expectations for Lecanemab: Insights from a Smallest Worthwhile Difference study [0.03%]
关于Lecanemab的公众接受度和期望:一项最小差异值得研究的见解
Aran Tajika,Kenji Omae,Ethan Sahker et al.
Aran Tajika et al.
Aim: To determine the smallest worthwhile difference (SWD) for lecanemab, a disease-modifying drug for Alzheimer's disease (AD), among the general Japanese population using a benefit-harm trade-off method. ...
Response to Durability of zuranolone in postpartum depression versus major depressive disorder [0.03%]
扎諾洛隆治疗产后抑郁症与重度抑郁障碍的疗效持久性答复研究
Masaki Kato,Kazuyuki Nakagome,Takamichi Baba et al.
Masaki Kato et al.
This article relates to Response to Durability of zuranolone in postpartum depression versus major depressive disorder. © 2026 The Author(s). Psychiatry...
Network-level disconnectivity tracks poststroke depressive symptom improvement [0.03%]
网络水平的断开程度跟踪卒中后抑郁症状的改善
Aleksi J Sihvonen,Sonia L E Brownsett,David A Copland et al.
Aleksi J Sihvonen et al.
Aims: Poststroke depression is the most common psychological condition following a stroke and can severely impact outcome. However, the neurobiological biomarkers associated with recovery of poststroke depression remain u...
Incomplete network restoration may be associated with higher relapse risk in women with major depressive disorder [0.03%]
不完整的网络恢复可能与女性重度抑郁复发风险增加有关
Yang Li,Xiwen Zhu,Shunming Yao et al.
Yang Li et al.
Aims: This study aimed to examine sex-specific alterations in structural brain network organization across different stages of major depressive disorder (MDD) and to explore whether stage-related network changes are assoc...
Hypnotic-associated falls across the diurnal cycle: Pharmacokinetic signal or delirium rhythm? [0.03%]
昼夜周期与睡眠相关的跌倒:药代动力学信号还是谵妄节奏?
Kyohei Otani
Kyohei Otani
Shishida and colleagues report that hypnotic-associated fall risk in hospitalized patients varies by drug class and time of day. We propose that the observed pattern may reflect a temporal misalignment between reactive as-needed hypnotic pr...
Effects of electroconvulsive therapy on cerebellar-cerebral functional connectivity in patients with treatment-resistant depression and their correlations with gene expression profiles [0.03%]
难治性抑郁症患者电休克治疗对脑小脑功能连接的影响及与基因表达的相关性研究
Leyi Zhang,Yiding Han,Dongsheng Lv et al.
Leyi Zhang et al.
Aims: Electroconvulsive therapy (ECT) is an effective intervention for treatment-resistant depression (TRD). Although prior studies have identified cerebellar functional alterations following ECT, cerebellar-cerebral func...
Abidemi I Otaiku
Abidemi I Otaiku
Genetics of bipolar disorder: Translating discoveries to biological insights and clinical decision support [0.03%]
双相障碍的遗传学:从发现到生物学认识和临床决策支持
Guy Hindley,Elise M Koch,Nadine Parker et al.
Guy Hindley et al.
Bipolar disorder (BD) is a clinically heterogenous mental disorder with a diversity in clinical trajectories and treatment response. Twin studies have shown that BD is highly heritable, with estimates ranging from 60% to 90%. However, our u...