Effects of Extended-Release Methylphenidate on Dopamine and Norepinephrine Transporters in Adults With Attention-Deficit/Hyperactivity Disorder: A Longitudinal Dual-Tracer PET Study [0.03%]
成人注意缺陷多动障碍患者中长效甲基苯丙胺对多巴胺和去甲肾上腺素转运蛋白的影响:双重示踪剂PET纵向研究
Masaki Oya,Kiwamu Matsuoka,Manabu Kubota et al.
Masaki Oya et al.
Aim: Attention-deficit/hyperactivity disorder (ADHD) is associated with dysregulation of dopamine and norepinephrine neurotransmission. Extended-release methylphenidate (MPH), a first-line treatment for ADHD, modulates th...
Glymphatic dysfunction as an indicator of disease burden and a potential biomarker in anti-NMDAR encephalitis [0.03%]
甘淋巴系统功能障碍作为抗N-甲基-D天冬氨酸受体脑炎疾病负担的指标和潜在生物标志物的作用
Han Cai,Dan Wu,Haotian Wu et al.
Han Cai et al.
Objective: This study aimed to explore the utility of these biomarkers for evaluating glymphatic dysfunction in patients with anti-N-methyl-D-aspartate receptor (anti-NMDAR) encephalitis and establish their effectiveness ...
A randomized, double-blinded, placebo-controlled study to evaluate the efficacy and safety of venlafaxine extended release in Japanese patients with generalized anxiety disorder [0.03%]
一项关于评估在患有广泛性焦虑障碍的日本患者中使用文拉法辛缓释片的有效性和安全性的随机、双盲、安慰剂对照研究
Tempei Otsubo,Koichiro Watanabe,Takeshi Inoue et al.
Tempei Otsubo et al.
Aim: The current study investigated the superiority of anxiolytic effects of venlafaxine extended release (ER) compared with placebo and its safety and tolerability in Japanese adult outpatients with generalized anxiety d...
Kenjiro Hosaka,Yoji Hirano
Kenjiro Hosaka
Genomic architecture of bipolar disorder in Japan: Insights from genomic structural equation modeling [0.03%]
日本双相情感障碍的基因组结构:来自基因组结构方程模型的启示
Hiroki Kimura,Yukako Nagasaki,Sawako Furukawa et al.
Hiroki Kimura et al.
Gastrointestinal obstruction due to the pica of plastic gloves in a long-term hospitalized patient with schizophrenia [0.03%]
一名长期住院的精神分裂症患者因吞食塑料手套导致肠梗阻
Shotaro Fujiwara,Hitomi Wake
Shotaro Fujiwara
An elderly inpatient with schizophrenia and pica developed bowel obstruction after ingesting plastic gloves; laparotomy removed eleven gloves. The case underscores the need to eliminate seemingly harmless plastic items from the environment ...
Case Reports
Psychiatry and clinical neurosciences. 2025 Oct 1. DOI:10.1111/pcn.13896 2025
Reevaluation of autopsied brains in psychiatric disorders based on current neuropathological classification [0.03%]
基于当前神经病理分类的精神疾病尸检脑的重新评估
Hiroshige Fujishiro
Hiroshige Fujishiro
Challenges in determining motor threshold for therapeutic repetitive transcranial magnetic stimulation: A paradigmatic case report of radiculopathy [0.03%]
重复经颅磁刺激治疗性刺激 Motor Threshold 确定的困境——一个因坐骨神经痛而进行 rTMS 治疗患者的案例报告
Joshua Tritsch,Amelie Völkel,Alkomiet Hasan et al.
Joshua Tritsch et al.
Mendelian randomization analyses uncover causal relationships between brain structural connectome and risk of psychiatric disorders [0.03%]
孟德尔随机化分析揭示了大脑结构连接组与精神障碍风险之间的因果关系
Kanwei Xiao,Xinle Chang,Chenfei Ye et al.
Kanwei Xiao et al.
Aims: Growing evidence suggests abnormalities of brain structural connectome in psychiatric disorders, but the causal relationships remain underexplored. Therefore, elucidating the causality is critical for deciphering th...