Impact of Aldosterone Synthase Inhibitor FAD286 on Steroid Hormone Profile in Human Adrenocortical Cells [0.03%]
醛固酮合酶抑制剂FAD286对人肾上腺皮质细胞类固醇激素谱的影响
Coy Brunssen,Anja Hofmann,Mirko Peitzsch et al.
Coy Brunssen et al.
Inhibition of aldosterone synthase (CYP11B2) is an alternative treatment option to mineralocorticoid receptor antagonism to prevent harmful aldosterone effects. FAD286 is the best characterized aldosterone synthase inhibitor. However, to da...
Effects of a Low-Calorie, Low-Carbohydrate Soy Containing Diet on Systemic Inflammation Among Patients with Nonalcoholic Fatty Liver Disease: A Parallel Randomized Clinical Trial [0.03%]
低卡路里低碳水化合物大豆饮食对非酒精性脂肪肝病患者全身炎症的影响：一项平行随机临床试验
Ali Hashemi Kani,Seyed Moayed Alavian,Ahmad Esmaillzadeh et al.
Ali Hashemi Kani et al.
Few studies have focused on the effects of a soy containing diet on inflammation and serum leptin level among patients with nonalcoholic fatty liver disease (NAFLD). Therefore, we aimed to determine the effects of such a diet in patients wi...
Zdravko Kamenov,Yavor Assyov,Petya Angelova et al.
Zdravko Kamenov et al.
The beneficial effects of testosterone on the metabolism and body composition of men are well established but the exact mechanisms of these effects are not clearly understood. A potential explanation might lie in the hormones, secreted from...
Prevalence, Clinical Features, and Natural History of Incidental Clinically Non-Functioning Pituitary Adenomas [0.03%]
无功能垂体腺瘤的流行病学、临床特征和自然史
Pedro Iglesias,Karina Arcano,Vanessa Triviño et al.
Pedro Iglesias et al.
The objective of the study was to assess the prevalence and clinical features of incidentally discovered clinically non-functioning pituitary adenoma (CNFPA) and to analyze its natural history. A multicenter retrospective study in patients ...
Role of Thyroid Deficiency on Adiponectin, Leptin, and Metabolic Status in Visceral Obesity: A Cross-Sectional Study [0.03%]
甲状腺功能减退对腹型肥胖患者脂联素、瘦素及糖代谢的影响：横断面研究
Lachezar B Lozanov,Desislava Gorcheva,Bojan S Lozanov et al.
Lachezar B Lozanov et al.
Genetic Alterations in Pendrin (SLC26A4) Gene in Adult Hypothyroid Patients [0.03%]
成人甲状腺功能减退患者 pendrin(SLC26A4)基因的改变
Sourav Mukherjee,Manalee Guha,Bidisha Adhikary et al.
Sourav Mukherjee et al.
Current study was aimed to screen the SLC26A4 gene in 127 nonautoimmune and noncongenital hypothyroid patients, who were under optimal iodine nutrition and devoid of any characteristics of Pendred syndrome from eastern part of Indian popula...
Body Composition is Different After Surgical or Pharmacological Remission of Cushing's Syndrome: A Prospective DXA Study [0.03%]
手术或药物缓解库欣综合征后的身体组成变化：一项关于DEXA的研究
Filippo Ceccato,Michela Boccato,Marialuisa Zilio et al.
Filippo Ceccato et al.
Patients with active Cushing's syndrome (CS) exhibit an increase of the visceral adipose tissue, increasing the risk of cardiovascular events. Until now, it is not yet clear whether remission of CS leads to a normalization of body compositi...
High Level of Progesteron Receptor Membrane Component 1 (PGRMC 1) in Tissue of Breast Cancer Patients is Associated with Worse Response to Anthracycline-Based Neoadjuvant Therapy [0.03%]
乳腺癌组织中高水平的黄体酮受体膜组分1(PGRMC1)与基于蒽环类药物的新辅助治疗反应较差相关
Marina Willibald,Isabel Wurster,Christoph Meisner et al.
Marina Willibald et al.
PGRMC1 is known to be highly expressed in breast cancer tissue and is associated with chemoresistance in breast cancer cells. However, its role in breast cancer signaling is not fully understood yet. In the present study, the expression sta...
Xiaolin Xu,Mingqi Sun,Jifeng Ye et al.
Xiaolin Xu et al.
Obesity has increased dramatically worldwide, which is associated with male infertility. Androgen deficiency, impaired spermatogenesis, and erectile dysfunction are characteristics of male infertility. The balance of androgens and estrogens...
Low-Carbohydrate-Diet Score and its Association with the Risk of Diabetes: A Systematic Review and Meta-Analysis of Cohort Studies [0.03%]
低碳水化合物饮食评分与糖尿病风险的关联：队列研究的系统评价和meta分析
Nazli Namazi,Bagher Larijani,Leila Azadbakht
Nazli Namazi
The association between a low-carbohydrate diet (LCD) score and the risk of diabetes mellitus (DM) is contradictory. This study is a systemic review of cohort studies that have focused on the association between the LCD score and DM. We sea...