Familial Hyperparathyroidism - Disorders of Growth and Secretion in Hormone-Secretory Tissue [0.03%]
家族性甲状旁腺功能亢进症-激素分泌组织生长和分泌障碍
Stephen J Marx,Delmar Muniz Lourenço Jr
Stephen J Marx
Six syndromes of familial hyperparathyroidism are compared: 1) Familial hypocalciuric hypercalcemia (FHH) expresses primary hyperparathyroidism (PHPT) beginning at birth with lifelong hypercalcemia. There is nonsuppressed PTH secretion from...
Can Screening and Confirmatory Testing in the Management of Patients with Primary Aldosteronism be Improved? [0.03%]
原发性醛固酮增多症患者的筛查和确诊测试可以改进吗？
Michael Stowasser,Ashraf Ahmed,Zeng Guo et al.
Michael Stowasser et al.
Widespread application of the plasma aldosterone/renin ratio (ARR) as a screening test has led to the recognition that primary aldosteronism (PA) is the most common specifically treatable and potentially curable form of hypertension, accoun...
Metabolic Endotoxemia-Activated Macrophages Promote Pancreatic β Cell Death via IFNβ-Xaf1 Pathway [0.03%]
代谢内毒素血症活化的巨噬细胞通过IFNβ-XAF1途径促进胰岛β细胞凋亡
Mitsudai Tsuruta,Misaki Iwashita,Takanori Shinjo et al.
Mitsudai Tsuruta et al.
Metabolic endotoxemia has been implicated in the pathogenesis of type 2 diabetes. In addition to adipose tissue inflammation, inflammatory cell infiltration is also observed in islets, although its effect on islets is largely unknown. We hy...
Thyroid Dysfunction States and Incident Cardiovascular Events: The Tehran Thyroid Study [0.03%]
甲状腺功能异常与心血管事件的关系：德黑兰甲状腺研究项目的资料
Maryam Tohidi,Arash Derakhshan,Samaneh Akbarpour et al.
Maryam Tohidi et al.
The objective of the study was to investigate the relation of different thyroid function states with the incidence of cardiovascular disease (CVD)/coronary heart disease (CHD) among a Middle-Eastern population with a high incidence of CVD/C...
Long-Term Follow-Up in Patients with Noninvasive Follicular Thyroid Neoplasm with Papillary-Like Nuclear Features (NIFTP) Without a Suspicion of Persistent Disease in Postoperative Assessment [0.03%]
术后评估中无持续性疾病疑虑的乳头状核特征非侵袭性滤泡型甲状腺肿瘤(NIFTP)患者的长期随访研究
Pedro Weslley Rosario,Gabriela Franco Mourão,Luís Fernando Faria Oliveira et al.
Pedro Weslley Rosario et al.
The objective was to determine whether negative assessment after surgery is a predictor of no relevant change of the results in subsequent evaluations in patients with noninvasive follicular thyroid neoplasm with papillary-like nuclear feat...
Screening for Type 1 Diabetes Risk in Newborns: The Freder1k Pilot Study in Saxony [0.03%]
新生儿1型糖尿病风险筛查：萨克森州的Freder1k试点研究
Angela Hommel,Florian Haupt,Petrina Delivani et al.
Angela Hommel et al.
An increased risk for type 1 diabetes can be identified using genetic and immune markers. The Freder1k study introduces genetic testing for type 1 diabetes risk within the context of the newborn screening in order to identify newborns with ...
Kosuke Inoue,Yuto Yamazaki,Yuya Tsurutani et al.
Kosuke Inoue et al.
Aldosterone-producing adenoma (APA) is sometimes accompanied with subclinical hypercortisolism. We investigated the ability of cortisol production in APA, both clinically and pathologically. A retrospective cohort study was conducted at Yok...
Ute I Scholl
Ute I Scholl
Over the past six years, the genetic basis of a significant fraction of primary aldosteronism (PA) cases has been solved. Breakthrough discoveries include the role of somatic variants in the KCNJ5, CACNA1D, ATP1A1, and ATP2B3 genes as cause...
John W Funder
John W Funder
The management of primary aldosteronism is widely varied within various published guidelines, with very little in the way of data supporting the choice of one variation over others. Current estimates of prevalence are probably accurate for ...
PreImplantation Factor (PIF*) Regulates Stress-Induced Adrenal Steroidogenesis and Anti-Inflammatory Cytokines: Potential Application for Bioartificial Adrenal Transplant [0.03%]
预植入因子(PIF)调节应激所致肾上腺皮质类固醇生成和抗炎细胞因子：用于生物人工肾上腺移植物的潜在应用能力
Mariya Balyura,Evgeny Gelfgat,Enrico Ullmann et al.
Mariya Balyura et al.
The main treatment algorithm for adrenal insufficiency is hormonal replacement, however, inadequate hormone substitution often leads to severe side effects. Adrenal cell transplantation could be a more effective alternative but would requir...