Single-Center Study of Therapeutic Apheresis in 24 Male Patients from the MENA Region: Reduction of Lipids, Inflammatory Markers, Autoantibodies, and Implications for Fatigue, Genetics, and Aging [0.03%]
单中心对24名来自中东和北非地区的男性患者的治疗性血浆置换研究：降低脂质、炎症标志物和自身抗体以及对疲劳、遗传学和衰老的影响
Charlotte Steenblock,Romy Walther,Yannick Kok et al.
Charlotte Steenblock et al.
Cardiovascular and metabolic disorders, particularly diabetes and obesity, are highly prevalent in the Middle East and North Africa (MENA) region, exhibiting some of the highest global incidence rates. These conditions significantly increas...
Association of METS-IR with Pregnancy Outcomes in Euthyroid Women: A Retrospective Cohort Study [0.03%]
甲状腺功能正常妇女METS-IR与妊娠结局的相关性：回顾性队列研究
Jiaying Lin,Qianwen Xie,Zize Guo et al.
Jiaying Lin et al.
The non-insulin-based metabolic score for insulin resistance (METS-IR) is a recently developed index aimed at being a practical and efficient alternative biomarker of insulin resistance (IR). This study aimed to investigate the association ...
Thyroid Hormones and Aging: Modulators of Mitochondrial Health, Metabolic Flexibility, and Longevity Pathways [0.03%]
甲状腺激素与衰老：线粒体健康、代谢可塑性及长寿途径的调节因素
Angela D Mazza
Angela D Mazza
Thyroid hormones (TH), primarily triiodothyronine (T3) and thyroxine (T4), are critical regulators of metabolic rate, mitochondrial function, and cellular repair mechanisms. Emerging evidence suggests that thyroid status may significantly i...
Vijayshwari Mishra,Ramenani Hari Babu
Vijayshwari Mishra
Allergic rhinitis (AR) is a widespread chronic condition caused by immune responses involving immunoglobulin E (IgE) when exposed to airborne allergens. It frequently coexists with conditions such as asthma and eye inflammation and represen...
Metabolic and Nutritional Outcomes After Sleeve Gastrostomy and Gastric Bypass in Adolescents: A Cohort Study with 1-Year Follow-Up [0.03%]
青少年袖状胃切除术和胃旁路术后代谢和营养结果：一项为期一年的队列研究
Faraneh Zolfaghari,Maryam Barzin,Maryam Mahdavi et al.
Faraneh Zolfaghari et al.
We conducted this study to compare the anthropometric and metabolic outcomes and nutritional status, after sleeve gastrostomy (SG) and gastric bypass (GB) in adolescents with severe obesity. We selected 219 adolescents with severe obesity (...
The Application of Assay- and Age-Specific Parathyroid Hormone (PTH) Reference Intervals Decreases the Diagnosis of Normocalcaemic Primary Hyperparathyroidism and Improves Diagnostic Concordance of PTH Assays [0.03%]
特异于检测和年龄的甲状旁腺素(PTH)参考区间的应用可减少正常血钙原发性甲状旁腺功能亢进症的诊断并提高对PTH检测结果的一致性
Halimah Khalil,Jonathan Fenn,Anna Sanders et al.
Halimah Khalil et al.
Parathyroid hormone (PTH) assays are not standardized and therefore PTH results are interpreted using manufacturer-provided assay-specific reference intervals. Assay-specific PTH reference intervals, however, do not account for between-assa...
Mechanisms of Action of Umbilical Cord Mesenchymal Stem Cells in Type 2 Diabetes Mellitus Treatment [0.03%]
脐带间充质干细胞在2型糖尿病治疗中的作用机制研究进展
Qiqiang Tao,Pinlei Lv,Xiao Dong et al.
Qiqiang Tao et al.
Type 2 diabetes mellitus (T2DM) is a chronic metabolic disease involving multiple organs. It affects the quality of life of patients significantly. Traditional treatments have certain limitations, such as side effects caused by long-term in...
Adverse Event Profile Differences Between Metyrapone and Osilodrostat: A Pharmacovigilance Study of the FDA Adverse Event Reporting System [0.03%]
甲吡酮和奥斯拉德若斯塔特的不良事件特征差异：FDA不良事件报告系统药物警戒研究
Chunyong Xia,Lanxin Hu,Ying Fan et al.
Chunyong Xia et al.
Metyrapone and osilodrostat are both steroidogenic inhibitors targeting the 11β-hydroxylase, yet their safety profile has not been comprehensively analyzed. The objective of this study is to compare the adverse events (AEs) associated with...
Kutay Kirdok,Nilufer Ozdemir,Sedat Can Guney et al.
Kutay Kirdok et al.
Immunoglobulin G4 (IgG4)-related diseases are a group of inflammatory conditions in which antibodies against IgG4 play a major role. IgG4-related diseases can affect thyroid gland. Our aim was to investigate whether there is a difference in...
Elevated Serum Creatine Kinase During the Treatment of Patients with Graves' Disease with Antithyroid Drugs: New Insights into an Old Issue [0.03%]
抗甲状腺药物治疗Graves病患者的血清肌酸激酶升高：老问题的新见解
Yuji Nagayama,Seigo Tachibana,Takashi Fukuda et al.
Yuji Nagayama et al.
Serum creatine kinase (CK) elevation can occur in some patients with Graves' disease treated with antithyroid drugs (ATDs). This study retrospectively investigated clinical characteristics and biochemical data of patients with Graves' disea...