Unraveling the Influence of Age, IQ, Education, and Negative Symptoms on Neurocognitive Performance in Schizophrenia: A Conditional Inference Tree Analysis [0.03%]
解开年龄、智商、教育和阴性症状对精神分裂症神经认知表现的影响：条件推断树分析
Xenia M Hart,Yasue Mitsukura,Robert R Bies et al.
Xenia M Hart et al.
Introduction: The complex nature of neurocognitive impairment in schizophrenia has been discussed in light of the mixed effects of antipsychotic drugs, psychotic symptoms, dopamine D2 receptor blockade, and intelligence q...
The Relevance of Integrating CYP2C19 Phenoconversion Effects into Clinical Pharmacogenetics [0.03%]
细胞色素2C19表型效应整合到临床药物遗传学中的相关性问题
Maike Scherf-Clavel,Heike Weber,Stefan Unterecker et al.
Maike Scherf-Clavel et al.
Introduction: CYP2D6 and CYP2C19 functional status as defined by genotype is modulated by phenoconversion (PC) due to pharmacokinetic interactions. As of today, there is no data on the effect size of PC for CYP2C19 functi...
Cannabidiol and its Potential Evidence-Based Psychiatric Benefits - A Critical Review [0.03%]
大麻二酚及其基于证据的精神病益处批判性综述
Inga Dammann,Cathrin Rohleder,F Markus Leweke
Inga Dammann
The endocannabinoid system shows promise as a novel target for treating psychiatric conditions. Cannabidiol (CBD), a naturally occurring cannabinoid, has been investigated in several psychiatric conditions, with diverse effects and an excel...
Effectiveness of Medical Cannabis for the Treatment of Depression: A Naturalistic Outpatient Study [0.03%]
大麻素对治疗抑郁症的有效性：一项自然主义门诊研究
Michael Specka,Udo Bonnet,Lisa Schmidberg et al.
Michael Specka et al.
Background: There is a lack of studies on the course and effectiveness of medical cannabis in the treatment of major depressive disorder (MDD). Methods: ...
Matthias Karst
Matthias Karst
Chronic pain is primarily conceptualized as a disease in its own right when it is associated with emotional distress and functional impairment. Pathophysiologically, dysfunction of the cortico-mesolimbic connectome is of major importance, w...
Julian Wellensiek,Michael Specka,Johannes Just et al.
Julian Wellensiek et al.
Introduction: Pharmacotherapy with drugs like naltrexone or acamprosate is a well-evaluated element in the treatment of alcohol dependence (AD). However, in many countries, these medications are rarely administered. The o...
Clinical Trial
Pharmacopsychiatry. 2024 Jan;57(1):21-29. DOI:10.1055/a-2190-4842 2024
Augmentation of Electroconvulsive Therapy with Oral Caffeine: A Retrospective Analysis of 40 Patients with Major Depression [0.03%]
口服咖啡因增强电休克治疗：40例重症抑郁症患者的回顾性分析
Peter Nyhuis,Dorothea Mücke,Michael Specka et al.
Peter Nyhuis et al.
Objective: Studies have demonstrated the efficacy of injectable caffeine as an augmentation method in electroconvulsive therapy (ECT). This study investigated whether orally administered caffeine increases seizure duratio...
The Effect of Electroconvulsive Therapy on Specific Catatonia Symptoms and Predictors of Late Response [0.03%]
电休克治疗对特定类 CATATONIA 症状的影响及迟发反应的预测因素
Sigrid Breit,Agnes Meyer,Wolfgang Schmitt et al.
Sigrid Breit et al.
Introduction: Electroconvulsive therapy (ECT) is known to be effective in the treatment of catatonia, reaching response rates of about 80 to 100%. It is indicated in cases of treatment resistance to benzodiazepines and in...
Fares Jaballah,Amina Aissa,Uta Ouali et al.
Fares Jaballah et al.
Prevalence of COVID-19 and Psychotropic Drug Treatment in Psychiatric In-patients in Germany in 2020: Results from a Nationwide Pilot Survey [0.03%]
德国2020年新冠肺炎疫情下精神病住院患者的心理药物治疗调查结果全国范围试点调查结果显示
Juliane K Mueller,Kira F Ahrens,Michael Bauer et al.
Juliane K Mueller et al.
Introduction: In patients with a pre-existing mental disorder, an increased risk for a first manifestation of a psychiatric disorder in COVID-19 patients, a more severe course of COVID-19 and an increased mortality have b...
Multicenter Study
Pharmacopsychiatry. 2023 Nov;56(6):227-238. DOI:10.1055/a-2177-3056 2023