Placental transfer of SSRI and SNRI antidepressants and effects on the neonate [0.03%]
选择性5-羟色胺再摄取抑制剂和钾胺去甲肾上腺素再摄取抑制剂类抗抑郁药的胎盘转运及其对新生儿的影响
J Rampono,K Simmer,K F Ilett et al.
J Rampono et al.
Introduction: We investigated placental transfer and neurobehavioural effects in neonates exposed to citalopram, escitalopram, fluoxetine, fluvoxamine, paroxetine or sertraline (SSRI's), or to venlafaxine (an SNRI). ...
Controlled Clinical Trial
Pharmacopsychiatry. 2009 May;42(3):95-100. DOI:10.1055/s-0028-1103296 2009
Rivastigmine reduces tobacco craving in alcohol-dependent smokers [0.03%]
酒依赖吸烟者尼古丁成瘾的 Rivastigmine 减缓疗法
A Diehl,H Nakovics,J Mutschler et al.
A Diehl et al.
Introduction: Although alcohol-dependent smokers represent an important group for applying smoking interventions, a sufficient pharmacotherapy has not been established in this high-risk group so far. ...
Randomized Controlled Trial
Pharmacopsychiatry. 2009 May;42(3):89-94. DOI:10.1055/s-0028-1103295 2009
Clinical benefits and cost effectiveness of vagus nerve stimulation in a long-term treatment of patients with major depression [0.03%]
迷走神经刺激治疗重度抑郁障碍长期疗效及成本效益分析
W Sperling,U Reulbach,J Kornhuber
W Sperling
Background: To evaluate clinical aspects and cost effectiveness of the treatment with vagus nerve stimulation (VNS), a group of 9 VNS-implanted patients and 9 age- and sex-matched patients suffering from treatment-resista...
Clinical Trial
Pharmacopsychiatry. 2009 May;42(3):85-8. DOI:10.1055/s-0028-1103294 2009
A Heinz,A Beck,J Wrase et al.
A Heinz et al.
An interplay of different neurotransmitter systems has been implicated in the development and maintenance of alcohol dependence. Here we focus on neuroadaptations in reward-related neurotransmitter systems and their impact on central proces...
Mechanistic studies of ethanol's interaction with the mesolimbic dopamine reward system [0.03%]
乙醇与中脑多巴胺奖赏系统相互作用的机理研究
B Söderpalm,E Löf,M Ericson
B Söderpalm
Alcoholism is a chronic recurring brain disorder causing the afflicted a multitude of social and health problems and enormous costs to society. The psychosocial and pharmacological treatment options available have but small to moderate effe...
N Wegener,M Koch
N Wegener
Endocannabinoids are synthesised from lipid precursors, are released from postsynaptic neurons in an activity-dependent way, and act as retrograde signalling messengers on specific G (i)-protein-coupled cannabinoid (CB (1)) receptors on pre...
D M Dietz,K C Dietz,E J Nestler et al.
D M Dietz et al.
Drug addiction is characterized by persistent behavioral and cellular plasticity throughout the brain's reward regions. Among the many neuroadaptations that occur following repeated drug administration are alterations in cell morphology inc...
Addiction memory as a specific, individually learned memory imprint [0.03%]
一种特殊的心瘾记忆印迹：特定的个体学习型记忆痕迹
J Böning
J Böning
The construct of "addiction memory" (AM) and its importance for relapse occurrence has been the subject of discussion for the past 30 years. Neurobiological findings from "social neuroscience" and biopsychological learning theory, in conjun...
P Dayan
P Dayan
Dopamine is intimately linked with the modes of action of drugs of addiction. However, although its role in the initiation of drug abuse seems relatively uncomplicated, its possible involvement in the development of compulsive drug taking, ...
M Le Moal
M Le Moal
Intrinsic vulnerability is central to the transition of recreational drug use to misuse. Several factors contribute to vulnerability, inherent or acquired, and they account for the huge individual differences observed concerning the propens...